Pre_GI: BLASTP Hits

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Query: NC_004631:4381724:4389499 Salmonella enterica subsp. enterica serovar Typhi Ty2, complete

Start: 4389499, End: 4389696, Length: 198

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This pathogenic strain of Salmonella typhi was isolated in the early 1970s. It contains no multidrug resistance plasmids and has been used for vaccine development. This serovar is a human-specific organism that causes the life-threatening illness Typhoid fever which is acquired by coming into contact with contaminated food or water. Annually, 17 million people are infected, with 600,000 fatalities, mostly in developing countries. It contains multiple fimbrial operons that may be used to create extracellular appendages for attachment and entry into host intestinal epithelial cells. Causes enteric infections. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_003198:4397074:440484944048494405046198Salmonella enterica subsp. enterica serovar Typhi str. CT18,hypothetical protein2e-30131
NC_011147:4297513:430733743073374307534198Salmonella enterica subsp. enterica serovar Paratyphi A strhypothetical protein2e-29127
NC_016863:4513106:452079645207964521011216Salmonella enterica subsp. enterica serovar Typhimurium str. UK-1putative cytoplasmic protein2e-26117
NC_016857:4573173:458094145809414581156216Salmonella enterica subsp. enterica serovar Typhimurium str. ST4/74putative cytoplasmic protein2e-26117
NC_016856:4563435:457319045731904573405216Salmonella enterica subsp. enterica serovar Typhimurium str. 14028Sputative cytoplasmic protein2e-26117
NC_016810:4573172:458094045809404581155216Salmonella enterica subsp. enterica serovar Typhimurium strhypothetical protein2e-26117
NC_003197:4551880:456036045603604560575216Salmonella typhimurium LT2, complete genomeputative cytoplasmic protein2e-26117
NC_006905:4486433:449414444941444494533390Salmonella enterica subsp. enterica serovar Choleraesuis strputative cytoplasmic protein2e-25114
NC_016832:4368948:437672343767234376866144Salmonella enterica subsp. enterica serovar Typhi str. P-stx-12,hypothetical protein5e-2096.3
NC_016831:4367000:437489643748964375231336Salmonella enterica subsp. enterica serovar Gallinarum/pullorumhypothetical protein1e-1685.1
NC_017046:4571833:457960145796014579762162Salmonella enterica subsp. enterica serovar Typhimurium str. 798hypothetical protein3e-1684
NC_016860:4649274:465775446577544657915162Salmonella enterica subsp. enterica serovar Typhimurium strputative cytoplasmic protein3e-1684
NC_011205:4564645:457440045744004574561162Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853hypothetical protein3e-1684
NC_012125:4481808:448951944895194489854336Salmonella enterica subsp. enterica serovar Paratyphi C straincytoplasmic protein8e-1682.4
NC_015761:4188250:4188250418825041978439594Salmonella bongori NCTC 12419, complete genomelarge repetitive protein8e-1475.9