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Query: NC_004631:3030580:3038629 Salmonella enterica subsp. enterica serovar Typhi Ty2, complete

Start: 3038629, End: 3039429, Length: 801

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This pathogenic strain of Salmonella typhi was isolated in the early 1970s. It contains no multidrug resistance plasmids and has been used for vaccine development. This serovar is a human-specific organism that causes the life-threatening illness Typhoid fever which is acquired by coming into contact with contaminated food or water. Annually, 17 million people are infected, with 600,000 fatalities, mostly in developing countries. It contains multiple fimbrial operons that may be used to create extracellular appendages for attachment and entry into host intestinal epithelial cells. Causes enteric infections. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016832:3020000:302726930272693028069801Salmonella enterica subsp. enterica serovar Typhi str. P-stx-12,Utative lipoprotein5e-157553
NC_003198:3042000:305272230527223053522801Salmonella enterica subsp. enterica serovar Typhi str. CT18,hypothetical protein5e-157553
NC_009792:923155:933775933775934584810Citrobacter koseri ATCC BAA-895, complete genomehypothetical protein3e-67254
NC_016776:2516149:252914025291402529916777Bacteroides fragilis 638R, complete genomehypothetical protein7e-1684.3
NC_006347:2375480:238847223884722389248777Bacteroides fragilis YCH46, complete genomeputative xylanase9e-1684.3
NC_004663:1365429:1373723137372313752701548Bacteroides thetaiotaomicron VPI-5482, complete genomeputative xylanase2e-1272.8