Pre_GI: BLASTP Hits

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Query: NC_004631:3030580:3037295 Salmonella enterica subsp. enterica serovar Typhi Ty2, complete

Start: 3037295, End: 3037693, Length: 399

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This pathogenic strain of Salmonella typhi was isolated in the early 1970s. It contains no multidrug resistance plasmids and has been used for vaccine development. This serovar is a human-specific organism that causes the life-threatening illness Typhoid fever which is acquired by coming into contact with contaminated food or water. Annually, 17 million people are infected, with 600,000 fatalities, mostly in developing countries. It contains multiple fimbrial operons that may be used to create extracellular appendages for attachment and entry into host intestinal epithelial cells. Causes enteric infections. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016832:3020000:302593530259353026333399Salmonella enterica subsp. enterica serovar Typhi str. P-stx-12,PilT protein domain protein3e-74276
NC_003198:3042000:305138830513883051786399Salmonella enterica subsp. enterica serovar Typhi str. CT18,hypothetical protein (assiciated with virulence)3e-74276
NC_017319:192482:198045198045198443399Shigella flexneri 2002017 plasmid pSFxv_1, complete sequenceplasmid maintenance protein1e-58224
NC_004851:191709:198117198117198515399Shigella flexneri 2a str. 301 plasmid pCP301, complete sequenceplasmid maintenance protein1e-58224
NC_015740:2407500:242307824230782423482405Pseudomonas stutzeri ATCC 17588 = LMG 11199 chromosome, completehypothetical protein3e-54209
NC_012912:4167429:417212441721244172528405Dickeya zeae Ech1591, complete genomePilT protein domain protein2e-50197
NC_015581:1043394:105384510538451054243399Thioalkalimicrobium cyclicum ALM1 chromosome, complete genomePilT protein domain-containing protein3e-46183
NC_010995:4297361:431397843139784314382405Cellvibrio japonicus Ueda107, complete genomePIN (PilT N terminus) domain1e-41167
NC_010278:1918000:192941819294181929816399Actinobacillus pleuropneumoniae serovar 3 str. JL03 chromosome,nucleic acid-binding protein9e-41165
NC_009053:1942973:196811919681191968505387Actinobacillus pleuropneumoniae L20, complete genomehypothetical protein2e-39160
NC_010939:1986263:199298919929891993387399Actinobacillus pleuropneumoniae serovar 7 str. AP76, completehypothetical protein3e-39160
NC_012660:5242392:525619252561925256599408Pseudomonas fluorescens SBW25 chromosome, complete genomehypothetical protein1e-38158
NC_002939:2697767:271099627109962711397402Geobacter sulfurreducens PCA, complete genomevirulence associated protein C5e-28122
NC_013205:644914:649702649702650109408Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446,PilT protein domain protein5e-27119
NC_013862:27991:626862686675408Allochromatium vinosum DSM 180 plasmid pALVIN02, complete sequencePilT protein domain protein1e-23108
NC_015578:61820:691206912069557438Treponema primitia ZAS-2 chromosome, complete genomeputative virulence-associated protein2e-23107
NC_016860:3995445:401015640101564010572417Salmonella enterica subsp. enterica serovar Typhimurium strVagD8e-23105
NC_015578:3980496:401721640172164017653438Treponema primitia ZAS-2 chromosome, complete genomevirulence associated protein C9e-23105
NC_010602:2244729:232456623245662324964399Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)'PilT protein1e-22104
NC_010842:2310756:232995223299522330350399Leptospira biflexa serovar Patoc strain 'Patoc 1 (Ames)' chromosomeVapC-like nucleic acid-binding protein1e-22104
NC_021150:3667176:368595836859583686368411Azotobacter vinelandii CA6, complete genomePilT domain-containing protein4e-21100
NC_012560:3667177:368595936859593686369411Azotobacter vinelandii DJ, complete genomePilT domain-containing protein4e-21100
NC_012751:409333:428549428549428965417Candidatus Hamiltonella defensa 5AT (Acyrthosiphon pisum), completeaddiction module, PIN domain protein5e-2199.4
NC_013285:1:177271772718143417Cronobacter turicensis plasmid pCTU3, complete sequencehypothetical protein1e-2098.2
NC_015942:2213710:222199022219902222394405Acidithiobacillus ferrivorans SS3 chromosome, complete genomePilT protein domain-containing protein3e-2097.1
NC_013161:4093322:410215241021524102553402Cyanothece sp. PCC 8802, complete genomePilT protein domain protein4e-1993.2
NC_012731:3411161:343273634327363433152417Klebsiella pneumoniae NTUH-K2044 chromosome, complete genomeputative DNA binding protein1e-1891.7
NC_014722:1191380:120180312018031202216414Burkholderia rhizoxinica HKI 454, complete genomeVIRULENCE-ASSOCIATED PROTEIN C3e-1890.5
NC_018000:2964500:296931229693122969749438Sinorhizobium fredii USDA 257 chromosome, complete genomeNtrR2 PIN domain-containing protein3e-1890.5
NC_006513:881120:901787901787902134348Azoarcus sp. EbN1, complete genomeconserved hypothetical protein, similar to virulence-associated protein VapC7e-1889.4
NC_005125:4557889:457538145753814575791411Gloeobacter violaceus PCC 7421, complete genomevirulence-associated protein VapC homolog1e-1788.2
NC_009615:4425500:445163544516354452045411Parabacteroides distasonis ATCC 8503 chromosome, complete genomeDNA binding protein4e-1786.7
NC_011662:1160887:116418911641891164608420Thauera sp. MZ1T, complete genomePilT protein domain protein6e-1786.3
NC_017098:32196:503285032850723396Spirochaeta africana DSM 8902 chromosome, complete genomeputative nucleic acid-binding protein, contains PIN domain1e-1685.1
NC_007507:101887:111429111429111830402Xanthomonas campestris pv. vesicatoria str. 85-10 plasmid pXCV183,hypothetical protein2e-1684.3
NC_014228:4408500:442340844234084423797390Xenorhabdus nematophila ATCC 19061, complete genomeconserved hypothetical protein (with PilT protein domain)1e-1582
NC_013889:1623697:163398116339811634379399Thioalkalivibrio sp. K90mix chromosome, complete genomePilT protein domain protein2e-1581.3
NC_019902:1:138671386714271405Thioalkalivibrio nitratireducens DSM 14787, complete genomeVapC toxin protein2e-1477.8
NC_011901:1398376:141724714172471417669423Thioalkalivibrio sulfidophilus HL-EbGr7 chromosome, completePilT protein domain-containing protein3e-1373.6
NC_010831:40000:577155771558161447Chlorobium phaeobacteroides BS1, complete genomePilT protein domain protein8e-1372.4
NC_012751:942315:953691953691954098408Candidatus Hamiltonella defensa 5AT (Acyrthosiphon pisum), completeaddiction module,PIN domain protein2e-1271.2
NC_015942:1711026:171449517144951714905411Acidithiobacillus ferrivorans SS3 chromosome, complete genomePilT protein domain-containing protein2e-1270.9
NC_015510:2487617:249169624916962492112417Haliscomenobacter hydrossis DSM 1100 chromosome, complete genomePilT protein domain-containing protein5e-1269.7
NC_008463:2467219:247897524789752479136162Pseudomonas aeruginosa UCBPP-PA14, complete genomehypothetical protein2e-1167.8
NC_009511:2921448:294077129407712941145375Sphingomonas wittichii RW1 chromosome, complete genomePilT domain-containing protein4e-1166.6
NC_012752:1:789078908285396Candidatus Hamiltonella defensa 5AT (Acyrthosiphon pisum) plasmidputative addiction module, PIN domain protein6e-1166.2
NC_008789:835909:877016877016877303288Halorhodospira halophila SL1, complete genomePilT protein-like protein9e-1165.5
NC_015382:266000:274647274647275057411Burkholderia gladioli BSR3 plasmid bgla_1p, complete sequencePIN domain protein1e-1064.7
NC_017080:1981788:200000020000002000299300Phycisphaera mikurensis NBRC 102666, complete genomehypothetical protein3e-1063.9
NC_011761:2344408:235943323594332359819387Acidithiobacillus ferrooxidans ATCC 23270 chromosome, completePIN domain-containing protein9e-1062.4
NC_011206:2239109:225417922541792254520342Acidithiobacillus ferrooxidans ATCC 53993, complete genomePilT protein domain protein4e-0960.1
NC_019902:1061432:109048510904851090715231Thioalkalivibrio nitratireducens DSM 14787, complete genome6e-0856.2
NC_013730:4811911:482453148245314824944414Spirosoma linguale DSM 74, complete genomePilT protein domain protein2e-0754.7
NC_009439:1174432:118093511809351181354420Pseudomonas mendocina ymp, complete genomePilT domain-containing protein4e-0753.5
NC_017276:774690:780110780110780502393Sulfolobus islandicus REY15A chromosome, complete genomeVapC-type toxin4e-0753.5
NC_017080:1981788:199977119997711999959189Phycisphaera mikurensis NBRC 102666, complete genomehypothetical protein9e-0752.4
NC_015510:4982255:500616850061685006557390Haliscomenobacter hydrossis DSM 1100 chromosome, complete genomePilT protein domain-containing protein1e-0651.6