Pre_GI: BLASTP Hits

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Query: NC_004631:2584244:2589303 Salmonella enterica subsp. enterica serovar Typhi Ty2, complete

Start: 2589303, End: 2589527, Length: 225

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This pathogenic strain of Salmonella typhi was isolated in the early 1970s. It contains no multidrug resistance plasmids and has been used for vaccine development. This serovar is a human-specific organism that causes the life-threatening illness Typhoid fever which is acquired by coming into contact with contaminated food or water. Annually, 17 million people are infected, with 600,000 fatalities, mostly in developing countries. It contains multiple fimbrial operons that may be used to create extracellular appendages for attachment and entry into host intestinal epithelial cells. Causes enteric infections. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016832:2581145:258620425862042586428225Salmonella enterica subsp. enterica serovar Typhi str. P-stx-12,hypothetical protein4e-28123
NC_003198:378844:391586391586391810225Salmonella enterica subsp. enterica serovar Typhi str. CT18,probable secreted protein4e-28123
NC_006511:2467763:247282324728232473047225Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCCprobable secreted protein4e-28123
NC_011147:2463299:246835924683592468583225Salmonella enterica subsp. enterica serovar Paratyphi A strhypothetical protein4e-28123
NC_011274:376970:389696389696389920225Salmonella enterica subsp. enterica serovar Gallinarum str. 287/91hypothetical protein4e-28123
NC_016831:2627515:263264326326432632867225Salmonella enterica subsp. enterica serovar Gallinarum/pullorumhypothetical protein4e-28123
NC_012125:373630:386402386402386581180Salmonella enterica subsp. enterica serovar Paratyphi C strainhypothetical protein4e-2096.7
NC_011149:361765:374550374550374729180Salmonella enterica subsp. enterica serovar Agona str. SL483,hypothetical protein4e-2096.7
NC_010102:2721374:272650227265022726681180Salmonella enterica subsp. enterica serovar Paratyphi B str. SPB7,hypothetical protein4e-2096.7
NC_011083:403022:438880438880439059180Salmonella enterica subsp. enterica serovar Heidelberg str. SL476,hypothetical protein1e-1995.1