Pre_GI: BLASTP Hits

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Query: NC_004631:1623511:1641649 Salmonella enterica subsp. enterica serovar Typhi Ty2, complete

Start: 1641649, End: 1642578, Length: 930

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This pathogenic strain of Salmonella typhi was isolated in the early 1970s. It contains no multidrug resistance plasmids and has been used for vaccine development. This serovar is a human-specific organism that causes the life-threatening illness Typhoid fever which is acquired by coming into contact with contaminated food or water. Annually, 17 million people are infected, with 600,000 fatalities, mostly in developing countries. It contains multiple fimbrial operons that may be used to create extracellular appendages for attachment and entry into host intestinal epithelial cells. Causes enteric infections. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_003198:1336894:133860413386041339533930Salmonella enterica subsp. enterica serovar Typhi str. CT18,putative oxidoreductase1e-172605
NC_011080:1750000:176732717673271768256930Salmonella enterica subsp. enterica serovar Newport str. SL254,isoflavone reductase5e-169593
NC_011149:1429523:143123314312331432162930Salmonella enterica subsp. enterica serovar Agona str. SL483,isoflavone reductase2e-168592
NC_017046:1709578:172768417276841728637954Salmonella enterica subsp. enterica serovar Typhimurium str. 798oxidoreductase2e-166585
NC_016857:1709695:172780117278011728754954Salmonella enterica subsp. enterica serovar Typhimurium str. ST4/74putative 2'-hydroxyisoflavone reductase2e-166585
NC_003197:1753663:177097117709711771900930Salmonella typhimurium LT2, complete genomeputative 2'-hydroxyisoflavone reductase2e-166584
NC_016810:1709695:172782517278251728754930Salmonella enterica subsp. enterica serovar Typhimurium strputative oxidoreductase2e-166584
NC_016856:1763640:178094917809491781878930Salmonella enterica subsp. enterica serovar Typhimurium str. 14028Sputative 2'-hydroxyisoflavone reductase2e-166584
NC_016860:1752000:176866217686621769591930Salmonella enterica subsp. enterica serovar Typhimurium strputative 2'-hydroxyisoflavone reductase2e-166584
NC_016863:1711832:172914117291411730070930Salmonella enterica subsp. enterica serovar Typhimurium str. UK-1putative 2'-hydroxyisoflavone reductase2e-166584
NC_011094:1726000:174414617441461745075930Salmonella enterica subsp. enterica serovar Schwarzengrund strisoflavone reductase6e-166583
NC_006511:1273162:127487212748721275800929Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC6e-92337
NC_005773:1333863:133513513351351336073939Pseudomonas syringae pv. phaseolicola 1448A, complete genomeisoflavone reductase6e-71267
NC_012660:2684981:269548926954892696427939Pseudomonas fluorescens SBW25 chromosome, complete genomeputative oxidoreductase4e-68258
NC_008542:197500:204123204123205076954Burkholderia cenocepacia HI2424 chromosome 1, complete sequenceNmrA family protein5e-66251
NC_016612:5231065:526710852671085268061954Klebsiella oxytoca KCTC 1686 chromosome, complete genomeNmrA family protein3e-64245
NC_015138:693865:6980946980946990981005Acidovorax avenae subsp. avenae ATCC 19860 chromosome, completeNmrA family protein5e-64244