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Query: NC_004631:1623511:1633929 Salmonella enterica subsp. enterica serovar Typhi Ty2, complete

Start: 1633929, End: 1634774, Length: 846

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This pathogenic strain of Salmonella typhi was isolated in the early 1970s. It contains no multidrug resistance plasmids and has been used for vaccine development. This serovar is a human-specific organism that causes the life-threatening illness Typhoid fever which is acquired by coming into contact with contaminated food or water. Annually, 17 million people are infected, with 600,000 fatalities, mostly in developing countries. It contains multiple fimbrial operons that may be used to create extracellular appendages for attachment and entry into host intestinal epithelial cells. Causes enteric infections. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_003198:1336894:134640813464081347253846Salmonella enterica subsp. enterica serovar Typhi str. CT18,putative lipoprotein1e-140499
NC_006511:1273162:128266512826651283510846Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCCputative lipoprotein1e-136486
NC_011147:1267005:127650812765081277353846Salmonella enterica subsp. enterica serovar Paratyphi A strlipoprotein1e-136486
NC_011094:1726000:173643317364331737278846Salmonella enterica subsp. enterica serovar Schwarzengrund strhypothetical protein8e-137486
NC_003197:1753663:176325717632571764102846Salmonella typhimurium LT2, complete genomeputative lipoprotein7e-137486
NC_016810:1709695:172011017201101720955846Salmonella enterica subsp. enterica serovar Typhimurium strputative lipoprotein7e-137486
NC_016856:1763640:177323417732341774079846Salmonella enterica subsp. enterica serovar Typhimurium str. 14028Sputative lipoprotein7e-137486
NC_016857:1709695:172011017201101720955846Salmonella enterica subsp. enterica serovar Typhimurium str. ST4/74putative lipoprotein7e-137486
NC_016860:1752000:176094817609481761793846Salmonella enterica subsp. enterica serovar Typhimurium strputative lipoprotein7e-137486
NC_016863:1711832:172142617214261722271846Salmonella enterica subsp. enterica serovar Typhimurium str. UK-1putative lipoprotein7e-137486
NC_006905:1766000:177638417763841777229846Salmonella enterica subsp. enterica serovar Choleraesuis strputative serine/threonine protein kinase1e-136485
NC_011149:1429523:143903314390331439878846Salmonella enterica subsp. enterica serovar Agona str. SL483,hypothetical protein6e-132470
NC_017046:1709578:171999317199931720793801Salmonella enterica subsp. enterica serovar Typhimurium str. 798lipoprotein4e-128457
NC_011080:1750000:175960917596091760205597Salmonella enterica subsp. enterica serovar Newport str. SL254,hypothetical protein2e-89328
NC_011740:1595381:160504116050411605910870Escherichia fergusonii ATCC 35469, complete genomeconserved hypothetical protein, putative exported protein2e-26119