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Query: NC_004631:1587000:1604450 Salmonella enterica subsp. enterica serovar Typhi Ty2, complete

Start: 1604450, End: 1604641, Length: 192

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This pathogenic strain of Salmonella typhi was isolated in the early 1970s. It contains no multidrug resistance plasmids and has been used for vaccine development. This serovar is a human-specific organism that causes the life-threatening illness Typhoid fever which is acquired by coming into contact with contaminated food or water. Annually, 17 million people are infected, with 600,000 fatalities, mostly in developing countries. It contains multiple fimbrial operons that may be used to create extracellular appendages for attachment and entry into host intestinal epithelial cells. Causes enteric infections. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017046:1669995:169369816936981693889192Salmonella enterica subsp. enterica serovar Typhimurium str. 798lipoprotein1e-29128
NC_011080:1709612:173331517333151733506192Salmonella enterica subsp. enterica serovar Newport str. SL254,hypothetical protein1e-29128
NC_011083:1761352:178506517850651785256192Salmonella enterica subsp. enterica serovar Heidelberg str. SL476,hypothetical protein1e-29128
NC_011149:1429523:146999914699991470190192Salmonella enterica subsp. enterica serovar Agona str. SL483,hypothetical protein1e-29128
NC_006905:1726416:175011817501181750309192Salmonella enterica subsp. enterica serovar Choleraesuis strputative outer membrane lipoprotein1e-29128
NC_011294:1465500:149193214919321492123192Salmonella enterica subsp. enterica serovar Enteritidis strlipoprotein1e-29128
NC_016810:1670112:169381516938151694006192Salmonella enterica subsp. enterica serovar Typhimurium strputative lipoprotein1e-29128
NC_016831:1468691:149239714923971492588192Salmonella enterica subsp. enterica serovar Gallinarum/pullorumputative lipoprotein1e-29128
NC_016832:1582273:160140016014001601591192Salmonella enterica subsp. enterica serovar Typhi str. P-stx-12,hypothetical protein1e-29128
NC_016857:1670112:169381516938151694006192Salmonella enterica subsp. enterica serovar Typhimurium str. ST4/74putative lipoprotein1e-29128
NC_016514:2079975:210312721031272103318192Enterobacter cloacae EcWSU1 chromosome, complete genomeprotein YnbE2e-2097.4
NC_013508:1862896:187997918799791880173195Edwardsiella tarda EIB202, complete genomeputative lipoprotein2e-1580.9
NC_013892:2332319:235325723532572353466210Xenorhabdus bovienii SS-2004 chromosome, complete genomehypothetical protein2e-1374.3
NC_015572:319725:341094341094341291198Methylomonas methanica MC09 chromosome, complete genomehypothetical protein2e-1167.8
NC_018691:3496420:350033635003363500536201Alcanivorax dieselolei B5 chromosome, complete genomeLipoprotein2e-1064.3
NC_015723:1347946:135721313572131357392180Cupriavidus necator N-1 chromosome 2, complete sequencehypothetical protein3e-0960.5