Pre_GI: BLASTP Hits

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Query: NC_004631:1091303:1103164 Salmonella enterica subsp. enterica serovar Typhi Ty2, complete

Start: 1103164, End: 1103340, Length: 177

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This pathogenic strain of Salmonella typhi was isolated in the early 1970s. It contains no multidrug resistance plasmids and has been used for vaccine development. This serovar is a human-specific organism that causes the life-threatening illness Typhoid fever which is acquired by coming into contact with contaminated food or water. Annually, 17 million people are infected, with 600,000 fatalities, mostly in developing countries. It contains multiple fimbrial operons that may be used to create extracellular appendages for attachment and entry into host intestinal epithelial cells. Causes enteric infections. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_003198:1867456:187779218777921877968177Salmonella enterica subsp. enterica serovar Typhi str. CT18,hypothetical protein2e-27120
NC_016857:1903426:191376619137661913939174Salmonella enterica subsp. enterica serovar Typhimurium str. ST4/74putative cytoplasmic protein2e-22104
NC_016856:1957263:196760319676031967776174Salmonella enterica subsp. enterica serovar Typhimurium str. 14028Sputative cytoplasmic protein2e-22104
NC_003197:1945858:195619819561981956371174Salmonella typhimurium LT2, complete genomeputative cytoplasmic protein2e-22104
NC_011147:1057259:107979310797931079933141Salmonella enterica subsp. enterica serovar Paratyphi A strhypothetical protein3e-1580.5
NC_006511:1063249:108578310857831085923141Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCChypothetical protein3e-1580.5
NC_016863:1905454:191582719158271915967141Salmonella enterica subsp. enterica serovar Typhimurium str. UK-1putative cytoplasmic protein4e-1580.1
NC_012125:1897611:192043819204381920578141Salmonella enterica subsp. enterica serovar Paratyphi C straincytoplasmic protein4e-1580.1
NC_006905:1961774:197216419721641972304141Salmonella enterica subsp. enterica serovar Choleraesuis strputative cytoplasmic protein1e-1478.6