Pre_GI: BLASTP Hits

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Query: NC_004631:1091303:1097908 Salmonella enterica subsp. enterica serovar Typhi Ty2, complete

Start: 1097908, End: 1098099, Length: 192

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This pathogenic strain of Salmonella typhi was isolated in the early 1970s. It contains no multidrug resistance plasmids and has been used for vaccine development. This serovar is a human-specific organism that causes the life-threatening illness Typhoid fever which is acquired by coming into contact with contaminated food or water. Annually, 17 million people are infected, with 600,000 fatalities, mostly in developing countries. It contains multiple fimbrial operons that may be used to create extracellular appendages for attachment and entry into host intestinal epithelial cells. Causes enteric infections. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012125:1897611:191445719144571914648192Salmonella enterica subsp. enterica serovar Paratyphi C strainhypothetical protein2e-30130
NC_011147:1057259:107445110744511074642192Salmonella enterica subsp. enterica serovar Paratyphi A strhypothetical protein2e-30130
NC_006905:1961774:197807819780781978269192Salmonella enterica subsp. enterica serovar Choleraesuis strputative inner membrane lipoprotein2e-30130
NC_006511:1063249:108044110804411080632192Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCChypothetical protein2e-30130
NC_003198:1867456:188303318830331883224192Salmonella enterica subsp. enterica serovar Typhi str. CT18,hypothetical protein2e-30130
NC_016832:1090274:109687910968791097037159Salmonella enterica subsp. enterica serovar Typhi str. P-stx-12,hypothetical protein3e-23107