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Query: NC_004631:1091303:1093704 Salmonella enterica subsp. enterica serovar Typhi Ty2, complete

Start: 1093704, End: 1093931, Length: 228

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This pathogenic strain of Salmonella typhi was isolated in the early 1970s. It contains no multidrug resistance plasmids and has been used for vaccine development. This serovar is a human-specific organism that causes the life-threatening illness Typhoid fever which is acquired by coming into contact with contaminated food or water. Annually, 17 million people are infected, with 600,000 fatalities, mostly in developing countries. It contains multiple fimbrial operons that may be used to create extracellular appendages for attachment and entry into host intestinal epithelial cells. Causes enteric infections. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016831:1734292:175134517513451751740396Salmonella enterica subsp. enterica serovar Gallinarum/pullorumputative phage encoded DNA-binding protein7e-39159
NC_003198:1867456:188720118872011887428228Salmonella enterica subsp. enterica serovar Typhi str. CT18,putative DNA-binding protein2e-38157
NC_011147:1057259:107024610702461070641396Salmonella enterica subsp. enterica serovar Paratyphi A strhypothetical protein4e-38156
NC_006905:1961774:198207919820791982474396Salmonella enterica subsp. enterica serovar Choleraesuis strputative DNA-binding protein4e-38156
NC_006511:1063249:107623610762361076631396Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCChypothetical protein4e-38156
NC_012125:1897611:191033019103301910647318Salmonella enterica subsp. enterica serovar Paratyphi C strainhypothetical protein2e-22104
NC_011294:1465500:147329514732951473624330Salmonella enterica subsp. enterica serovar Enteritidis strphage encoded DNA-binding protein6e-1476.3
NC_009801:1419324:142765314276531428048396Escherichia coli E24377A, complete genomehypothetical protein7e-1269.3