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Query: NC_004557:2607073 Clostridium tetani E88, complete genome

Start: 2607073, End: 2630384, Length: 23312

Host Lineage: Clostridium tetani; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain is a virulent nonsporulating variant of strain Massachusetts used in vaccine production. Causes tetanus. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. Known opportunistic toxin-producing pathogens in animals and humans. Some species are capable of producing organic solvents (acetone, ethanol, etc,), molecular hydrogen and other useful compounds. This organism causes tetanus (lockjaw) in humans. At the tissue level, the bacterium then releases an exotoxin called tetanospasmin that causes certain nervous system irregularities by means of retrograde tramsmission through neurons to the brain. If nervous impulses cannot be checked by normal inhibitory mechanisms, it produces the generalized muscular spasms characteristic of tetanus.

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_020291:40330004033000405659923600Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genome3e-83317BLASTN svgBLASTP svg
NC_008261:676000*67600070224526246Clostridium perfringens ATCC 13124, complete genome2e-81311BLASTN svgBLASTP svg
NC_008262:654000*65400067859924600Clostridium perfringens SM101, complete genome4e-79303BLASTN svgBLASTP svg
NC_003366:72885972885975493526077Clostridium perfringens str. 13, complete genome4e-79303BLASTN svgBLASTP svg
NC_008593:153014*15301417175318740Clostridium novyi NT, complete genome5e-23117BLASTN svgBLASTP svg
NC_018704:81733*8173311606034328Amphibacillus xylanus NBRC 15112, complete genome3e-18101BLASTN svgBLASTP svg
NC_010001:40406640406642359919534Clostridium phytofermentans ISDg, complete genome2e-1695.6BLASTN svgBLASTP svg
NC_014166:681290*68129070228720998Arcobacter nitrofigilis DSM 7299 chromosome, complete genome8e-1693.7BLASTN svgBLASTP svg
NC_020291:117983*11798315068032698Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genome3e-1591.7BLASTN svgBLASTP svg
NC_004557:162670*16267018073018061Clostridium tetani E88, complete genome5e-1487.7BLASTN svgBLASTP svg
NC_021182:11880001188000121083922840Clostridium pasteurianum BC1, complete genome1e-1179.8BLASTN svgBLASTP svg
NC_013316:4018451*4018451404145623006Clostridium difficile R20291, complete genome1e-1179.8BLASTN svgBLASTP svg
NC_009089:4140764*4140764416313522372Clostridium difficile 630, complete genome1e-1179.8BLASTN svgBLASTP svg
NC_008599:1325155*1325155134694521791Campylobacter fetus subsp. fetus 82-40, complete genome1e-1179.8BLASTN svgBLASTP svg
NC_004557:2711702*2711702274444632745Clostridium tetani E88, complete genome1e-1179.8BLASTN svgBLASTP svg
NC_004432:1310322*1310322134172431403Mycoplasma penetrans HF-2, complete genome5e-1177.8BLASTN svgBLASTP svg
NC_008593:22818962281896230590024005Clostridium novyi NT, complete genome5e-1177.8BLASTN svgBLASTP svg
NC_015977:3215770*3215770327589560126Roseburia hominis A2-183 chromosome, complete genome5e-1177.8BLASTN svgBLASTP svg
NC_012563:4004709*4004709403727332565Clostridium botulinum A2 str. Kyoto, complete genome7e-1073.8BLASTN svgBLASTP svg
NC_009850:445000*44500046374218743Arcobacter butzleri RM4018, complete genome7e-1073.8BLASTN svgBLASTP svg
NC_008262:2649289*2649289270467655388Clostridium perfringens SM101, complete genome3e-0971.9BLASTN svgBLASTP svg
NC_014328:4387303*4387303445852771225Clostridium ljungdahlii ATCC 49587 chromosome, complete genome4e-0867.9BLASTN svgBLASTP svg
NC_008011:213386*21338624949536110Lawsonia intracellularis PHE/MN1-00, complete genome2e-0765.9BLASTN svgBLASTP svg
NC_010723:173280*17328022135248073Clostridium botulinum E3 str. Alaska E43, complete genome2e-0765.9BLASTN svgBLASTP svg
NC_015978:412856*41285644063427779Lactobacillus sanfranciscensis TMW 1.1304 chromosome, complete2e-0765.9BLASTN svgBLASTP svg
NC_018664:2459994*2459994248609926106Clostridium acidurici 9a chromosome, complete genome7e-0763.9BLASTN svgBLASTP svg
NC_014909:86000*8600012150135502Candidatus Blochmannia vafer str. BVAF chromosome, complete genome7e-0763.9BLASTN svgBLASTP svg
NC_014328:4471995*4471995450215530161Clostridium ljungdahlii ATCC 49587 chromosome, complete genome7e-0763.9BLASTN svgBLASTP svg
NC_019978:2036779*2036779205929022512Halobacteroides halobius DSM 5150, complete genome3e-0661.9BLASTN svgBLASTP svg
NC_010516:3807780*3807780384035532576Clostridium botulinum B1 str. Okra, complete genome3e-0661.9BLASTN svgBLASTP svg
NC_008312:5357567*5357567538230924743Trichodesmium erythraeum IMS101, complete genome3e-0661.9BLASTN svgBLASTP svg
NC_006055:769418*76941879599926582Mesoplasma florum L1, complete genome3e-0661.9BLASTN svgBLASTP svg