Pre_GI: BLASTP Hits

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Query: NC_004557:806878:813005 Clostridium tetani E88, complete genome

Start: 813005, End: 815008, Length: 2004

Host Lineage: Clostridium tetani; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain is a virulent nonsporulating variant of strain Massachusetts used in vaccine production. Causes tetanus. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. Known opportunistic toxin-producing pathogens in animals and humans. Some species are capable of producing organic solvents (acetone, ethanol, etc,), molecular hydrogen and other useful compounds. This organism causes tetanus (lockjaw) in humans. At the tissue level, the bacterium then releases an exotoxin called tetanospasmin that causes certain nervous system irregularities by means of retrograde tramsmission through neurons to the brain. If nervous impulses cannot be checked by normal inhibitory mechanisms, it produces the generalized muscular spasms characteristic of tetanus.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_004557:806878:8150588150588161191062Clostridium tetani E88, complete genomeinternalin-like/N-acetylmuramoyl-L-alanine amidase4e-140499
NC_018515:595500:6153216153216173332013Desulfosporosinus meridiei DSM 13257 chromosome, complete genomecell wall-binding protein4e-77289
NC_011837:3052000:3055001305500130565571557Clostridium kluyveri NBRC 12016, complete genomehypothetical protein1e-72275
NC_009698:2265475:2286166228616622877821617Clostridium botulinum A str. Hall chromosome, complete genomeamidase1e-67258
NC_016584:1436710:1446961144696114515414581Desulfosporosinus orientis DSM 765 chromosome, complete genomegluconolactonase6e-61236
NC_014328:522045:5416295416295431881560Clostridium ljungdahlii ATCC 49587 chromosome, complete genomeputative cell wall-binding protein3e-60233
NC_014328:3336000:3349827334982733513021476Clostridium ljungdahlii ATCC 49587 chromosome, complete genomeputative cell wall-binding protein1e-57225
NC_016584:3847663:3863026386302638676574632Desulfosporosinus orientis DSM 765 chromosome, complete genomecell wall-binding protein3e-57223
NC_014328:3823902:3831411383141138378246414Clostridium ljungdahlii ATCC 49587 chromosome, complete genomeputative cell wall-binding protein1e-55218
NC_004557:691944:7116347116347131511518Clostridium tetani E88, complete genomeputative S-layer protein/internalin A-like/N-acetylmuramoyl-L-alanine amidase2e-55217
NC_015520:1683616:1690889169088917007769888Mahella australiensis 50-1 BON chromosome, complete genomeIg family protein5e-55216
NC_014328:2426921:2439223243922324422493027Clostridium ljungdahlii ATCC 49587 chromosome, complete genomeputative surface/cell-adhesion protein2e-52207
NC_014328:2426921:2436213243621324391222910Clostridium ljungdahlii ATCC 49587 chromosome, complete genomeputative cell wall-binding protein5e-52206
NC_004557:806878:8175568175568231985643Clostridium tetani E88, complete genomeputative surface/cell-adhesion protein4e-51203
NC_014328:2426921:2430181243018124320701890Clostridium ljungdahlii ATCC 49587 chromosome, complete genomeputative cell wall-binding protein5e-51202
NC_018515:1406816:1421052142105214269855934Desulfosporosinus meridiei DSM 13257 chromosome, complete genomehypothetical protein1e-50201
NC_018515:1406816:1414764141476414208416078Desulfosporosinus meridiei DSM 13257 chromosome, complete genomehypothetical protein4e-50200
NC_004557:806878:8164028164028174691068Clostridium tetani E88, complete genomeputative surface/cell-adhesion protein3e-49196
NC_016935:2567039:2582935258293525875124578Paenibacillus mucilaginosus 3016 chromosome, complete genomehypothetical protein2e-47190
NC_018867:179975:1917141917141932281515Dehalobacter sp. CF chromosome, complete genomehypothetical protein3e-46187
NC_018866:108812:1241191241191256331515Dehalobacter sp. DCA chromosome, complete genomeN-acetylmuramoyl-L-alanine amidase3e-46187
NC_004557:806878:8068788068788085841707Clostridium tetani E88, complete genomeputative surface/cell-adhesion protein2e-42174
NC_010376:186510:1934951934951954681974Finegoldia magna ATCC 29328, complete genomeputative N-acetylmuramoyl-L-alanine amidase1e-38161
NC_015172:1075592:1095774109577411005974824Syntrophobotulus glycolicus DSM 8271 chromosome, complete genomecell wall binding repeat 2-containing protein9e-38159
NC_014328:938393:9539089539089561212214Clostridium ljungdahlii ATCC 49587 chromosome, complete genomeputative cell wall-binding protein9e-37155
NC_007907:2249607:2251795225179522543742580Desulfitobacterium hafniense Y51, complete genomehypothetical protein5e-36153
NC_018515:595500:6087396087396120533315Desulfosporosinus meridiei DSM 13257 chromosome, complete genomeWD40-like repeat protein1e-35152
NC_006270:3627974:3627974362797436301182145Bacillus licheniformis ATCC 14580, complete genomemodifier protein of major autolysin LytC (CWBP76)6e-36152
NC_006322:3628143:3628143362814336302872145Bacillus licheniformis ATCC 14580, complete genomeLytB6e-36152
NC_007907:3722500:3752354375235437540301677Desulfitobacterium hafniense Y51, complete genomehypothetical protein2e-33144
NC_011837:2856500:2873537287353728750391503Clostridium kluyveri NBRC 12016, complete genomehypothetical protein3e-33144
NC_009706:2925000:2942035294203529435131479Clostridium kluyveri DSM 555 chromosome, complete genomecell wall binding protein3e-33144
NC_015520:224136:2513782513782550163639Mahella australiensis 50-1 BON chromosome, complete genomepeptidase S8 and S53 subtilisin kexin sedolisin6e-33142
NC_011830:4722607:4756991475699147589041914Desulfitobacterium hafniense DCB-2, complete genomeIg domain protein7e-33142
NC_011830:3528665:3530497353049735326172121Desulfitobacterium hafniense DCB-2, complete genomeputative cell wall binding repeat 2-containing protein2e-32141
NC_011830:4722607:4749674474967447513861713Desulfitobacterium hafniense DCB-2, complete genomeIg domain protein group 2 domain protein1e-31138
NC_016894:3527364:3527364352736435311793816Acetobacterium woodii DSM 1030 chromosome, complete genomeputative cell surface protein2e-31137
NC_015172:2986867:3028296302829630304672172Syntrophobotulus glycolicus DSM 8271 chromosome, complete genomecell wall binding repeat 2-containing protein9e-31135
NC_000964:3658000:3658149365814936596391491Bacillus subtilis subsp. subtilis str. 168, complete genomeN-acetylmuramoyl-L-alanine amidase (major autolysin) (CWBP49)5e-30133
NC_014328:2426921:2442291244229124442551965Clostridium ljungdahlii ATCC 49587 chromosome, complete genomeputative cell wall-binding protein2e-29130
NC_014328:1108479:1114075111407511163602286Clostridium ljungdahlii ATCC 49587 chromosome, complete genomeputative surface-layer protein4e-28126
NC_013315:1707293:1727689172768917300882400Clostridium difficile CD196 chromosome, complete genomepenicillin-binding protein8e-28125
NC_000964:3658000:3659678365967836617952118Bacillus subtilis subsp. subtilis str. 168, complete genomemodifier protein of major autolysin LytC (CWBP76)3e-27124
NC_017195:3459567:3459567345956734616842118Bacillus subtilis subsp. subtilis str. RO-NN-1 chromosome, completeputative cell wall binding repeat 2 family2e-27124
NC_015520:2567329:2581460258146025833461887Mahella australiensis 50-1 BON chromosome, complete genometransglutaminase domain-containing protein2e-27124
NC_010376:49185:6033260332680177686Finegoldia magna ATCC 29328, complete genomeputative N-acetylmuramoyl-L-alanine amidase4e-27123
NC_015172:1471501:14866231486623149964213020Syntrophobotulus glycolicus DSM 8271 chromosome, complete genomecell wall binding repeat 2-containing protein7e-27122
NC_011830:4722607:4758940475894047613272388Desulfitobacterium hafniense DCB-2, complete genomeputative cell wall binding repeat 2-containing protein9e-27122
NC_010376:28812:3102331023369055883Finegoldia magna ATCC 29328, complete genomecell wall-associated serine proteinase precursor1e-26122
NC_010376:28812:3724337243419074665Finegoldia magna ATCC 29328, complete genomeN-acetylmuramoyl-L-alanine amidase2e-26121
NC_014169:2234249:2246905224690522489532049Bifidobacterium longum subsp. longum JDM301 chromosome, completehypothetical protein1e-26121
NC_007907:2249607:2257635225763522635325898Desulfitobacterium hafniense Y51, complete genomehypothetical protein3e-26120
NC_011837:3052000:3056664305666430599813318Clostridium kluyveri NBRC 12016, complete genomehypothetical protein4e-26120
NC_014833:3362500:3374340337434033755121173Ruminococcus albus 7 chromosome, complete genomehypothetical protein2e-25118
NC_009089:3241918:3241918324191832443292412Clostridium difficile 630, complete genomecell surface protein (putative cell surface-associated cysteine protease)4e-25117
NC_014328:3294086:3295757329575732967911035Clostridium ljungdahlii ATCC 49587 chromosome, complete genomeputative cell wall-binding protein4e-25117
NC_011830:4399642:440620144062014407181981Desulfitobacterium hafniense DCB-2, complete genomeputative cell wall binding repeat 2-containing protein3e-25117
NC_007907:2995889:3013521301352130148401320Desulfitobacterium hafniense Y51, complete genomehypothetical protein3e-25117
NC_007907:3722500:3759012375901237609401929Desulfitobacterium hafniense Y51, complete genomehypothetical protein3e-25117
NC_016023:1769925:1807545180754518089721428Bacillus coagulans 36D1 chromosome, complete genomeLPXTG-motif cell wall anchor domain-containing protein5e-25116
NC_014328:522045:5382445382445415763333Clostridium ljungdahlii ATCC 49587 chromosome, complete genomeputative surface-layer protein7e-24112
NC_009089:3241918:3254929325492932565151587Clostridium difficile 630, complete genomesurface surface protein1e-23112
NC_013315:3073652:3084146308414630857351590Clostridium difficile CD196 chromosome, complete genomesurface protein3e-23110
NC_017179:3082000:3092098309209830936871590Clostridium difficile BI1, complete genomesurface protein3e-23110
NC_007907:5104476:5125684512568451277202037Desulfitobacterium hafniense Y51, complete genomehypothetical protein2e-23110
NC_007907:3722500:3756571375657137589492379Desulfitobacterium hafniense Y51, complete genomehypothetical protein1e-22108
NC_018515:595500:6120286120286152403213Desulfosporosinus meridiei DSM 13257 chromosome, complete genomecell wall-binding protein2e-22108
NC_009089:3241918:3252559325255932547182160Clostridium difficile 630, complete genomecell surface protein (S-layer precursor protein)4e-22107
NC_010418:188138:1983021983021993901089Clostridium botulinum A3 str. Loch Maree plasmid pCLK, completeamidase domain protein4e-22107
NC_009664:4696961:4744702474470247468612160Kineococcus radiotolerans SRS30216, complete genomeputative cell wall binding repeat 2-containing protein7e-22106
NC_009089:3241918:3247683324768332495541872Clostridium difficile 630, complete genomecell surface protein (putative S-layer protein precursor)5e-22106
NC_009664:452195:4521954521954539971803Kineococcus radiotolerans SRS30216, complete genomeputative cell wall binding repeat 2-containing protein1e-21105
NC_017179:3082000:3084729308472930866001872Clostridium difficile BI1, complete genomeS-layer protein1e-21105
NC_013315:3073652:3076777307677730786481872Clostridium difficile CD196 chromosome, complete genomeS-layer protein1e-21105
NC_014830:335380:3522053522053539561752Intrasporangium calvum DSM 43043 chromosome, complete genomeDomain of unknown function DUF19941e-21105
NC_016584:5388500:5392334539233453949882655Desulfosporosinus orientis DSM 765 chromosome, complete genomecell wall-binding protein2e-21104
NC_015520:224136:2438912438912469293039Mahella australiensis 50-1 BON chromosome, complete genomecell wall binding repeat 2-containing protein2e-21104
NC_009664:3969609:3988523398852339899501428Kineococcus radiotolerans SRS30216, complete genomeputative cell wall binding repeat 2-containing protein6e-21103
NC_009697:419443:4275024275024285901089Clostridium botulinum A str. ATCC 19397 chromosome, completeamidase6e-21102
NC_010376:1711182:1722867172286717242971431Finegoldia magna ATCC 29328, complete genomeN-acetylmuramoyl-L-alanine amidase8e-21102
NC_018515:4334240:4356270435627043588942625Desulfosporosinus meridiei DSM 13257 chromosome, complete genomecell wall-binding protein2e-1998.2
NC_018515:4442500:4457444445744444590811638Desulfosporosinus meridiei DSM 13257 chromosome, complete genomecell wall-binding protein3e-1997.8
NC_017179:3082000:3093906309390630955011596Clostridium difficile BI1, complete genomecell surface protein2e-1997.8
NC_013315:3073652:3085954308595430875551602Clostridium difficile CD196 chromosome, complete genomecell surface protein2e-1997.8
NC_009089:3241918:3256734325673432583351602Clostridium difficile 630, complete genomecell surface protein3e-1997.4
NC_017179:3082000:3082047308204730838821836Clostridium difficile BI1, complete genomecell surface protein6e-1996.7
NC_013315:3073652:3074095307409530759301836Clostridium difficile CD196 chromosome, complete genomecell surface protein6e-1996.7
NC_017179:3082000:3095874309587430977541881Clostridium difficile BI1, complete genomecell surface protein9e-1995.9
NC_013315:3073652:3087922308792230898021881Clostridium difficile CD196 chromosome, complete genomecell surface protein9e-1995.9
NC_017177:91993:1253731253731267491377Clostridium difficile BI1, complete genomehemagglutinin/adhesin1e-1895.1
NC_009089:3241918:3245004324500432468361833Clostridium difficile 630, complete genomecell surface protein3e-1894
NC_017179:3082000:3089596308959630918722277Clostridium difficile BI1, complete genomeS-layer precursor protein3e-1894
NC_013315:3073652:3081644308164430839202277Clostridium difficile CD196 chromosome, complete genomeS-layer protein3e-1894
NC_009089:3241918:3258702325870232605881887Clostridium difficile 630, complete genomecell surface protein8e-1892.8
NC_018515:4474000:4494291449429144985144224Desulfosporosinus meridiei DSM 13257 chromosome, complete genomecell wall-binding protein2e-1791.7
NC_014246:611275:61127561127562342112147Mobiluncus curtisii ATCC 43063 chromosome, complete genomebacterial Ig-like domain-containing protein4e-1790.1
NC_013316:1081044:1093266109326610953052040Clostridium difficile R20291, complete genomecell surface protein (putative N-acetylmuramoyl-L-alanine amidase)1e-1688.6
NC_009089:1202261:1214547121454712165862040Clostridium difficile 630, complete genomecell surface protein (putative N-acetylmuramoyl-L-alanine amidase)1e-1688.6
NC_016584:5420823:5427391542739154290761686Desulfosporosinus orientis DSM 765 chromosome, complete genomecell wall-binding protein2e-1687.8
NC_009089:1202261:1217070121707012191032034Clostridium difficile 630, complete genomecell surface protein (putative N-acetylmuramoyl-L-alanine amidase)3e-1687.8
NC_013316:1081044:1095797109579710978302034Clostridium difficile R20291, complete genomecell surface protein (putative N-acetylmuramoyl-L-alanine amidase)3e-1687.8
NC_004557:455895:4601364601364633783243Clostridium tetani E88, complete genomeputative S-layer protein/N-acetylmuramoyl-L-alanine amidase2e-1584.3
NC_015172:2986867:3032883303288330365513669Syntrophobotulus glycolicus DSM 8271 chromosome, complete genomecell wall binding repeat 2-containing protein3e-1480.9
NC_011830:4722607:4761677476167747650843408Desulfitobacterium hafniense DCB-2, complete genomeputative cell wall binding repeat 2-containing protein8e-1169.3
NC_016582:1707756:1729883172988317313011419Streptomyces bingchenggensis BCW-1 chromosome, complete genomehypothetical protein3e-1067.8
NC_014831:1906691:1910633191063319118711239Thermaerobacter marianensis DSM 12885 chromosome, complete genomecell wall binding repeat 2-containing protein3e-1067.4
NC_015172:1429266:144638214463821446657276Syntrophobotulus glycolicus DSM 8271 chromosome, complete genomeputative cell wall binding repeat 2-containing protein7e-0962.8
NC_000868:1386592:1389242138924213902431002Pyrococcus abyssi GE5, complete genomehypothetical protein4e-0653.9