Pre_GI: BLASTP Hits

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Query: NC_004557:2607073:2617884 Clostridium tetani E88, complete genome

Start: 2617884, End: 2619281, Length: 1398

Host Lineage: Clostridium tetani; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain is a virulent nonsporulating variant of strain Massachusetts used in vaccine production. Causes tetanus. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. Known opportunistic toxin-producing pathogens in animals and humans. Some species are capable of producing organic solvents (acetone, ethanol, etc,), molecular hydrogen and other useful compounds. This organism causes tetanus (lockjaw) in humans. At the tissue level, the bacterium then releases an exotoxin called tetanospasmin that causes certain nervous system irregularities by means of retrograde tramsmission through neurons to the brain. If nervous impulses cannot be checked by normal inhibitory mechanisms, it produces the generalized muscular spasms characteristic of tetanus.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012780:430653:4306534306534320981446Eubacterium eligens ATCC 27750 plasmid unnamed, complete sequencehypothetical protein9e-83307
NC_016641:2773757:2797894279789427993121419Paenibacillus terrae HPL-003 chromosome, complete genomeC4-dicarboxylate anaerobic carrier2e-81303
NC_010718:2860096:2874496287449628758781383Natranaerobius thermophilus JW/NM-WN-LF, complete genomeC4-dicarboxylate anaerobic carrier4e-60232
NC_014364:3500041:3501368350136835027921425Spirochaeta smaragdinae DSM 11293 chromosome, complete genomeC4-dicarboxylate anaerobic carrier3e-55216
NC_007168:195638:1956381956381970321395Staphylococcus haemolyticus JCSC1435, complete genomehypothetical protein3e-51203
NC_009831:2045811:2056843205684320583841542Shewanella sediminis HAW-EB3, complete genomeC4-dicarboxylate anaerobic carrier3e-45183
NC_016751:1979201:1980549198054919820361488Marinitoga piezophila KA3 chromosome, complete genomehypothetical protein4e-39162
NC_008710:900586:9140649140649154791416Borrelia turicatae 91E135, complete genomearginine/ornithine antiporter6e-39162
NC_009495:1516000:1535500153550015370351536Clostridium botulinum A str. ATCC 3502 chromosome, complete genomeC4-dicarboxylate transporter1e-36154
NC_010673:908940:9173459173459187631419Borrelia hermsii DAH, complete genomearginine/ornithine antiporter3e-35150
NC_008601:246583:2759112759112774221512Francisella tularensis subsp. novicida U112, complete genomeC4-dicarboxylate anaerobic carrier7e-34145
NC_011900:2107133:2127634212763421291451512Streptococcus pneumoniae ATCC 700669, complete genomeC4-dicarboxylate anaerobic carrier protein4e-33142
NC_015389:809474:8315898315898330521464Coriobacterium glomerans PW2 chromosome, complete genomeC4-dicarboxylate anaerobic carrier4e-33142
NC_012466:2008000:2027031202703120285421512Streptococcus pneumoniae JJA, complete genomearginine-ornithine antiporter3e-32140
NC_012467:1997484:2018682201868220201931512Streptococcus pneumoniae P1031, complete genomearginine-ornithine antiporter2e-32140
NC_008533:1935500:1952608195260819541191512Streptococcus pneumoniae D39, complete genomehypothetical protein2e-32140
NC_010582:2091138:2112506211250621140171512Streptococcus pneumoniae CGSP14, complete genomehypothetical protein2e-32140
NC_003098:1925783:1945106194510619466171512Streptococcus pneumoniae R6, complete genomehypothetical protein2e-32140
NC_012468:2069238:2088265208826520897761512Streptococcus pneumoniae 70585, complete genomearginine-ornithine antiporter2e-32140
NC_014498:2127000:2143987214398721454981512Streptococcus pneumoniae 670-6B chromosome, complete genomearginine-ornithine antiporter2e-32140
NC_015696:220798:2242602242602256751416Francisella sp. TX077308 chromosome, complete genomeArginine/ornithine antiporter ArcD8e-31135
NC_014541:2510819:2513700251370025151571458Ferrimonas balearica DSM 9799 chromosome, complete genomeC4-dicarboxylate anaerobic carrier9e-30131
NC_017986:2548720:2569814256981425712531440Pseudomonas putida ND6 chromosome, complete genomeC4-dicarboxylate anaerobic carrier9e-30131
NC_014614:1090000:1106312110631211078261515Clostridium sticklandii, complete genomeconserved membrane protein of unknown function7e-28125
NC_012691:2614603:2683425268342526848701446Tolumonas auensis DSM 9187, complete genomeC4-dicarboxylate anaerobic carrier3e-27123
NC_003454:865368:8826568826568841671512Fusobacterium nucleatum subsp. nucleatum ATCC 25586, completeTransporter2e-25117
NC_004461:205068:2170382170382186031566Staphylococcus epidermidis ATCC 12228, complete genomehypothetical protein1e-24114
NC_004347:3028000:303755130375513038111561Shewanella oneidensis MR-1, complete genome8e-1582
NC_008601:246583:275553275553275780228Francisella tularensis subsp. novicida U112, complete genome2e-0861.2
NC_013515:183088:2226022226022240561455Streptobacillus moniliformis DSM 12112, complete genomeC4-dicarboxylate anaerobic carrier5e-0859.7