Some Help

Query: NC_004557:1141558:1155935 Clostridium tetani E88, complete genome

Start: 1155935, End: 1157392, Length: 1458

Host Lineage: Clostridium tetani; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain is a virulent nonsporulating variant of strain Massachusetts used in vaccine production. Causes tetanus. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. Known opportunistic toxin-producing pathogens in animals and humans. Some species are capable of producing organic solvents (acetone, ethanol, etc,), molecular hydrogen and other useful compounds. This organism causes tetanus (lockjaw) in humans. At the tissue level, the bacterium then releases an exotoxin called tetanospasmin that causes certain nervous system irregularities by means of retrograde tramsmission through neurons to the brain. If nervous impulses cannot be checked by normal inhibitory mechanisms, it produces the generalized muscular spasms characteristic of tetanus.

Search Results with any or all of these Fields

Host Accession, e.g. NC_0123..Host Description, e.g. Clostri...
Host Lineage, e.g. archae, Proteo, Firmi...
Host Information, e.g. soil, Thermo, Russia

SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_014328:3434478:3452727345272734542021476Clostridium ljungdahlii ATCC 49587 chromosome, complete genomehypothetical protein1e-109397
NC_009495:2479465:2498876249887625003961521Clostridium botulinum A str. ATCC 3502 chromosome, complete genomehypothetical protein9e-102370
NC_011772:2763863:2782534278253427840511518Bacillus cereus G9842, complete genomephage protein9e-1272
NC_017208:1831918:1868014186801418695311518Bacillus thuringiensis serovar chinensis CT-43 chromosome, completePhage protein2e-1171.2
NC_004722:1804788:1836654183665418381711518Bacillus cereus ATCC 14579, complete genomePhage protein2e-1170.9