Pre_GI: BLASTP Hits

Some Help

Query: NC_004557:1141558:1147821 Clostridium tetani E88, complete genome

Start: 1147821, End: 1148450, Length: 630

Host Lineage: Clostridium tetani; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain is a virulent nonsporulating variant of strain Massachusetts used in vaccine production. Causes tetanus. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. Known opportunistic toxin-producing pathogens in animals and humans. Some species are capable of producing organic solvents (acetone, ethanol, etc,), molecular hydrogen and other useful compounds. This organism causes tetanus (lockjaw) in humans. At the tissue level, the bacterium then releases an exotoxin called tetanospasmin that causes certain nervous system irregularities by means of retrograde tramsmission through neurons to the brain. If nervous impulses cannot be checked by normal inhibitory mechanisms, it produces the generalized muscular spasms characteristic of tetanus.




Search Results with any or all of these Fields

Host Accession, e.g. NC_0123..Host Description, e.g. Clostri...
Host Lineage, e.g. archae, Proteo, Firmi...
Host Information, e.g. soil, Thermo, Russia



SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012658:2525931:253263025326302533259630Clostridium botulinum Ba4 str. 657 chromosome, complete genomehypothetical protein5e-83306
NC_009495:2479465:251033625103362510965630Clostridium botulinum A str. ATCC 3502 chromosome, complete genomehypothetical protein7e-83306
NC_021182:2536000:254733525473352547982648Clostridium pasteurianum BC1, complete genomehypothetical protein1e-66252
NC_011837:1969144:197706219770621977544483Clostridium kluyveri NBRC 12016, complete genomehypothetical protein1e-51202
NC_009706:2023912:204555920455592046041483Clostridium kluyveri DSM 555 chromosome, complete genomehypothetical protein1e-51202
NC_009706:1972000:197722619772261977708483Clostridium kluyveri DSM 555 chromosome, complete genomehypothetical protein1e-51202
NC_009617:1897887:190994819099481910592645Clostridium beijerinckii NCIMB 8052 chromosome, complete genomehypothetical protein2e-31135