Pre_GI: BLASTP Hits

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Query: NC_004557:1141558:1147396 Clostridium tetani E88, complete genome

Start: 1147396, End: 1147824, Length: 429

Host Lineage: Clostridium tetani; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain is a virulent nonsporulating variant of strain Massachusetts used in vaccine production. Causes tetanus. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. Known opportunistic toxin-producing pathogens in animals and humans. Some species are capable of producing organic solvents (acetone, ethanol, etc,), molecular hydrogen and other useful compounds. This organism causes tetanus (lockjaw) in humans. At the tissue level, the bacterium then releases an exotoxin called tetanospasmin that causes certain nervous system irregularities by means of retrograde tramsmission through neurons to the brain. If nervous impulses cannot be checked by normal inhibitory mechanisms, it produces the generalized muscular spasms characteristic of tetanus.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009495:2479465:251095325109532511375423Clostridium botulinum A str. ATCC 3502 chromosome, complete genomehypothetical protein4e-44176
NC_012658:2525931:253324725332472533669423Clostridium botulinum Ba4 str. 657 chromosome, complete genomehypothetical protein6e-40162
NC_021182:2536000:254691425469142547333420Clostridium pasteurianum BC1, complete genomeProtein of unknown function (DUF1064)6e-36149
NC_009617:1897887:190951619095161909944429Clostridium beijerinckii NCIMB 8052 chromosome, complete genomehypothetical protein8e-30129
NC_009706:1972000:197770119777011978117417Clostridium kluyveri DSM 555 chromosome, complete genomehypothetical protein2e-29127
NC_009706:2023912:204603420460342046450417Clostridium kluyveri DSM 555 chromosome, complete genomehypothetical protein2e-29127
NC_011837:1969144:197753719775371977953417Clostridium kluyveri NBRC 12016, complete genomehypothetical protein2e-29127
NC_020164:1677452:170376717037671704171405Staphylococcus warneri SG1, complete genomehypothetical protein5e-26116
NC_009782:920272:930768930768931172405Staphylococcus aureus subsp. aureus Mu3, complete genomehypothetical protein3e-24110
NC_002758:918827:929323929323929727405Staphylococcus aureus subsp. aureus Mu50, complete genomehypothetical protein3e-24110
NC_017337:1107930:111955411195541119958405Staphylococcus aureus subsp. aureus ED133 chromosome, completehypothetical phage-related protein2e-24110
NC_017337:1990298:200397320039732004377405Staphylococcus aureus subsp. aureus ED133 chromosome, completehypothetical protein2e-24110
UCMB5137:120656:125621125621126085465Bacillus atrophaeus UCMB-5137hypothetical protein1e-21101
NC_014551:576000:585269585269585727459Bacillus amyloliquefaciens DSM 7, complete genomephage protein1e-2098.2
NC_019842:1172944:118314111831411183599459Bacillus amyloliquefaciens subsp. plantarum AS43.3 chromosome,hypothetical protein4e-2096.7
NC_009487:921884:932016932016932420405Staphylococcus aureus subsp. aureus JH9 chromosome, completehypothetical protein1e-1995.1
NC_009632:921759:931891931891932295405Staphylococcus aureus subsp. aureus JH1 chromosome, completehypothetical protein1e-1995.1
NC_002951:351029:368013368013368417405Staphylococcus aureus subsp. aureus COL, complete genomehypothetical protein2e-1994.4
NC_007795:2034000:206241920624192062823405Staphylococcus aureus subsp. aureus NCTC 8325, complete genomephi ETA orf 25-like protein2e-1994.4
NC_016928:1538901:156220215622021562606405Staphylococcus aureus subsp. aureus M013 chromosome, completehypothetical protein3e-1993.6
NC_007622:1842000:187503618750361875440405Staphylococcus aureus RF122, complete genomehypothetical phage-related protein3e-1993.6
NC_007795:1922000:195415419541541954558405Staphylococcus aureus subsp. aureus NCTC 8325, complete genomephi ETA orf 25-like protein3e-1993.6
NC_003212:57061:909589095891362405Listeria innocua Clip11262, complete genomehypothetical protein7e-1785.9
NC_009633:2592000:262312926231292623506378Alkaliphilus metalliredigens QYMF chromosome, complete genomehypothetical protein7e-1785.9
NC_003210:2380419:238817923881792388583405Listeria monocytogenes EGD-e, complete genomehypothetical protein9e-1785.5
NC_003212:2413824:243051224305122430916405Listeria innocua Clip11262, complete genomehypothetical protein1e-1685.1
NC_011660:2924397:293993129399312940206276Listeria monocytogenes HCC23 chromosome, complete genomehypothetical protein1e-1168.6
NC_020207:1906803:191530619153061915665360Enterococcus faecium NRRL B-2354, complete genomehypothetical protein6e-1062.8
NC_020207:1170000:117295911729591173318360Enterococcus faecium NRRL B-2354, complete genomehypothetical protein1e-0962
NC_009674:2985878:300949730094973009886390Bacillus cytotoxicus NVH 391-98 chromosome, complete genomehypothetical protein6e-0752.8