Pre_GI: BLASTP Hits

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Query: NC_004557:1141558:1146049 Clostridium tetani E88, complete genome

Start: 1146049, End: 1146927, Length: 879

Host Lineage: Clostridium tetani; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain is a virulent nonsporulating variant of strain Massachusetts used in vaccine production. Causes tetanus. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. Known opportunistic toxin-producing pathogens in animals and humans. Some species are capable of producing organic solvents (acetone, ethanol, etc,), molecular hydrogen and other useful compounds. This organism causes tetanus (lockjaw) in humans. At the tissue level, the bacterium then releases an exotoxin called tetanospasmin that causes certain nervous system irregularities by means of retrograde tramsmission through neurons to the brain. If nervous impulses cannot be checked by normal inhibitory mechanisms, it produces the generalized muscular spasms characteristic of tetanus.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_003212:2413824:243569424356942436626933Listeria innocua Clip11262, complete genomehypothetical protein4e-30131
NC_002758:2101137:211312421131242114017894Staphylococcus aureus subsp. aureus Mu50, complete genomehypothetical protein7e-27121
NC_002745:2018761:203592520359252036818894Staphylococcus aureus subsp. aureus N315, complete genomehypothetical protein7e-27121
NC_010079:2102856:211527621152762116169894Staphylococcus aureus subsp. aureus USA300_TCH1516, completepossible DNA replication protein DnaD7e-27121
NC_009487:2148316:215821721582172159110894Staphylococcus aureus subsp. aureus JH9 chromosome, completeprimosome subunit DnaD7e-27121
NC_009487:362475:372003372003372896894Staphylococcus aureus subsp. aureus JH9 chromosome, completeprimosome subunit DnaD7e-27121
NC_009632:2148767:215809121580912158984894Staphylococcus aureus subsp. aureus JH1 chromosome, completeprimosome subunit DnaD7e-27121
NC_009632:361229:372073372073372966894Staphylococcus aureus subsp. aureus JH1 chromosome, completeprimosome subunit DnaD7e-27121
NC_017343:1963912:198107419810741981967894Staphylococcus aureus subsp. aureus ECT-R 2, complete genomednaD and phage-associated domain protein7e-27121
NC_017338:2034698:206725420672542068147894Staphylococcus aureus subsp. aureus JKD6159 chromosome, completehypothetical protein3e-26119
NC_017351:2074000:210098121009812101874894Staphylococcus aureus subsp. aureus 11819-97 chromosome, completednaD domain protein1e-25117
NC_014551:865254:875602875602876375774Bacillus amyloliquefaciens DSM 7, complete genomeReplication protein O5e-24111
NC_017190:852171:861499861499862272774Bacillus amyloliquefaciens LL3 chromosome, complete genomereplication protein O6e-24111
NC_006138:432000:447098447098448036939Desulfotalea psychrophila LSv54, complete genomehypothetical protein4e-1479
NC_009641:2101579:211896021189602119844885Staphylococcus aureus subsp. aureus str. Newman chromosome,phage regulatory protein3e-1272.8
NC_015425:34861:381903819039107918Clostridium botulinum BKT015925 chromosome, complete genomeputative DNA replication protein DnaD9e-1064.3
NC_008593:37456:389313893139923993Clostridium novyi NT, complete genomeDNA replication protein DnaD1e-0757
NC_017208:694500:701810701810702613804Bacillus thuringiensis serovar chinensis CT-43 chromosome, completePhage replication protein1e-0757
NC_011660:2924397:293249629324962933416921Listeria monocytogenes HCC23 chromosome, complete genomegp493e-0755.8
NC_014650:603500:621711621711622664954Geobacillus sp. Y4.1MC1 chromosome, complete genomeprimosome subunit DnaD3e-0755.8
NC_015687:3766000:378872137887213789707987Clostridium acetobutylicum DSM 1731 chromosome, complete genomeDNA replication protein DnaD7e-0754.7
NC_003030:3763054:378713837871383788124987Clostridium acetobutylicum ATCC 824, complete genomeDNA replication protein DnaD7e-0754.7
NC_017295:3762622:378649037864903787476987Clostridium acetobutylicum EA 2018 chromosome, complete genomeDNA replication protein DnaD7e-0754.7
NC_003212:57061:849218492185832912Listeria innocua Clip11262, complete genomehypothetical protein1e-0653.9
NC_021175:597968:606176606176606856681Streptococcus oligofermentans AS 1.3089, complete genomereplication protein2e-0653.5
NC_020210:2969862:2996116299611629974171302Geobacillus sp. GHH01, complete genomehypothetical protein4e-0652.4
NC_004557:81362:837638376384737975Clostridium tetani E88, complete genomeDNA replication protein dnaD6e-0651.6