Pre_GI: BLASTP Hits

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Query: NC_004557:1141558:1143708 Clostridium tetani E88, complete genome

Start: 1143708, End: 1145051, Length: 1344

Host Lineage: Clostridium tetani; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain is a virulent nonsporulating variant of strain Massachusetts used in vaccine production. Causes tetanus. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. Known opportunistic toxin-producing pathogens in animals and humans. Some species are capable of producing organic solvents (acetone, ethanol, etc,), molecular hydrogen and other useful compounds. This organism causes tetanus (lockjaw) in humans. At the tissue level, the bacterium then releases an exotoxin called tetanospasmin that causes certain nervous system irregularities by means of retrograde tramsmission through neurons to the brain. If nervous impulses cannot be checked by normal inhibitory mechanisms, it produces the generalized muscular spasms characteristic of tetanus.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_011660:2924397:293070129307012931660960Listeria monocytogenes HCC23 chromosome, complete genomegp474e-86318
NC_003212:2413824:243746124374612438420960Listeria innocua Clip11262, complete genomegp47 [Bacteriophage A118]4e-86318
NC_003212:57061:831268312684085960Listeria innocua Clip11262, complete genomehypothetical protein1e-85317
NC_020207:1170000:117007411700741171015942Enterococcus faecium NRRL B-2354, complete genomehypothetical protein1e-73277
NC_017208:694500:699875699875700810936Bacillus thuringiensis serovar chinensis CT-43 chromosome, completehypothetical protein9e-73274
NC_013411:597235:605043605043605978936Geobacillus sp. Y412MC61, complete genomephage-type endonuclease1e-72273
NC_014915:2963500:299795729979572998892936Geobacillus sp. Y412MC52 chromosome, complete genomephage-type endonuclease1e-72273
NC_020134:420500:425829425829426758930Clostridium stercorarium subsp. stercorarium DSM 8532, completephage-type endonuclease5e-62238
NC_015437:1494777:151102615110261511961936Selenomonas sputigena ATCC 35185 chromosome, complete genomephage-type endonuclease1e-58227
NC_006322:1415863:143031814303181431256939Bacillus licheniformis ATCC 14580, complete genomeYqaJ4e-54212
NC_016077:1278104:129056412905641291553990Acidaminococcus intestini RyC-MR95 chromosome, complete genomehypothetical protein3e-50199
NC_012491:3736167:375674137567413757610870Brevibacillus brevis NBRC 100599, complete genomehypothetical protein2e-48193
NC_014831:8965:209172091721873957Thermaerobacter marianensis DSM 12885 chromosome, complete genomephage-type endonuclease1e-47191
NC_014551:576000:581026581026581529504Bacillus amyloliquefaciens DSM 7, complete genomenuclease; skin element8e-47188
NC_016935:1636278:164999116499911650863873Paenibacillus mucilaginosus 3016 chromosome, complete genomehypothetical protein2e-44180
NC_016935:6464201:648593264859326486804873Paenibacillus mucilaginosus 3016 chromosome, complete genomehypothetical protein3e-44179
NC_009524:1627414:1641944164194416429601017Psychrobacter sp. PRwf-1 chromosome, complete genomephage-like protein endonuclease-like protein8e-44178
NC_013446:1648556:1697430169743016984671038Comamonas testosteroni CNB-2, complete genomehypothetical protein8e-41168
NC_008542:197500:224462224462225457996Burkholderia cenocepacia HI2424 chromosome 1, complete sequenceGP477e-40165
NC_012691:2476223:250369125036912504674984Tolumonas auensis DSM 9187, complete genomephage-type endonuclease1e-39164
NC_006270:1415001:142959014295901430393804Bacillus licheniformis ATCC 14580, complete genomephage related protein6e-39162
NC_016147:2337244:2356166235616623571911026Pseudoxanthomonas spadix BD-a59 chromosome, complete genomehypothetical protein2e-38160
NC_015424:3520783:352182835218283522817990Aeromonas veronii B565 chromosome, complete genomehypothetical protein2e-38160
NC_011000:2732330:277524827752482776243996Burkholderia cenocepacia J2315 chromosome 1, complete sequencehypothetical protein2e-38160
NC_011000:1262324:130772813077281308723996Burkholderia cenocepacia J2315 chromosome 1, complete sequenceputative phage-related protein1e-38160
NC_007651:3064530:313445231344523135447996Burkholderia thailandensis E264 chromosome I, complete sequencegp471e-38160
NC_009439:1297851:1332336133233613333401005Pseudomonas mendocina ymp, complete genomePhage-related protein endonuclease-like protein1e-37158
NC_015740:2407500:2423866242386624248731008Pseudomonas stutzeri ATCC 17588 = LMG 11199 chromosome, completehypothetical protein1e-37157
NC_018080:2288700:2314463231446323154671005Pseudomonas aeruginosa DK2 chromosome, complete genomehypothetical protein1e-37157
NC_010322:5293652:5302021530202153030251005Pseudomonas putida GB-1 chromosome, complete genomephage-like protein endonuclease-like protein4e-37156
NC_007298:1759881:1781164178116417821921029Dechloromonas aromatica RCB, complete genomehypothetical protein4e-37155
NC_015422:3184823:3200291320029132013191029Alicycliphilus denitrificans K601 chromosome, complete genomephage-type endonuclease5e-37155
NC_018691:3525430:3556761355676135577621002Alcanivorax dieselolei B5 chromosome, complete genomePutative phage-type endonuclease domain protein6e-37155
NC_008570:1143578:118475711847571185746990Aeromonas hydrophila subsp. hydrophila ATCC 7966, complete genomehypothetical protein2e-36153
NC_014153:3084356:309883230988323099818987Thiomonas intermedia K12 chromosome, complete genomephage-type endonuclease2e-36153
NC_015381:1588742:160550416055041606499996Burkholderia gladioli BSR3 chromosome 1, complete sequencehypothetical protein6e-36152
NC_012559:768939:775693775693776430738Laribacter hongkongensis HLHK9, complete genomeYqaJ domain containing protein4e-36152
NC_007651:72952:1277131277131287891077Burkholderia thailandensis E264 chromosome I, complete sequencegp474e-36152
NC_017506:1222000:1233383123338312344231041Marinobacter adhaerens HP15 chromosome, complete genomehypothetical protein1e-35150
NC_008782:2568027:2602657260265726036851029Acidovorax sp. JS42, complete genomehypothetical protein2e-35150
NC_017506:1100679:1116535111653511175751041Marinobacter adhaerens HP15 chromosome, complete genomehypothetical protein1e-34147
NC_009138:1843998:1865449186544918664501002Herminiimonas arsenicoxydans, complete genomeconserved hypothetical protein in putative prophage region9e-34144
NC_016002:2946702:296392329639232964906984Pseudogulbenkiania sp. NH8B, complete genomeYqaJ-like viral recombinase family protein2e-33143
NC_011770:2499432:2512855251285525138561002Pseudomonas aeruginosa LESB58, complete genomePhage-related protein predicted endonuclease-like protein3e-33143
NC_009076:3564500:360056136005613601463903Burkholderia pseudomallei 1106a chromosome I, complete sequencegp471e-32141
NC_007969:2885249:2887731288773128888371107Psychrobacter cryohalolentis K5, complete genomehypothetical protein2e-31137
NC_007712:1954808:197837719783771979273897Sodalis glossinidius str. 'morsitans', complete genomehypothetical protein1e-25117
NC_014551:576000:581552581552581965414Bacillus amyloliquefaciens DSM 7, complete genomenuclease; skin element3e-23109
NC_012658:2525931:2539415253941525404641050Clostridium botulinum Ba4 str. 657 chromosome, complete genomeputative YqaJ4e-23109
NC_012791:651480:660681660681661424744Variovorax paradoxus S110 chromosome 1, complete genomephage-type endonuclease7e-22105
NC_012590:2117027:215335821533582154356999Corynebacterium aurimucosum ATCC 700975, complete genomehypothetical protein2e-1687
NC_015379:908904:956893956893957534642Pseudomonas brassicacearum subsp. brassicacearum NFM421 chromosome,Hypothetical protein5e-1582.8
NC_015942:1711026:172566717256671726149483Acidithiobacillus ferrivorans SS3 chromosome, complete genome2e-1480.5
NC_006087:2439252:245544024554402456435996Leifsonia xyli subsp. xyli str. CTCB07, complete genomephage recombination protein5e-1169.7
NC_012559:1301988:130679213067921307043252Laribacter hongkongensis HLHK9, complete genomePhage-related protein, predicted endonuclease4e-0860.1
NC_008826:84218:8743787437885131077Methylibium petroleiphilum PM1 plasmid RPME01, complete sequencehypothetical protein1e-0758.2
NC_016801:1123733:1143685114368511447101026Corynebacterium diphtheriae C7 (beta) chromosome, complete genomehypothetical protein1e-0655.1
NC_007716:196000:203917203917204555639Aster yellows witches'-broom phytoplasma AYWB, complete genomehypothetical protein8e-0652.4