Pre_GI: BLASTP Hits

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Query: NC_004557:1141558:1141558 Clostridium tetani E88, complete genome

Start: 1141558, End: 1142370, Length: 813

Host Lineage: Clostridium tetani; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain is a virulent nonsporulating variant of strain Massachusetts used in vaccine production. Causes tetanus. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. Known opportunistic toxin-producing pathogens in animals and humans. Some species are capable of producing organic solvents (acetone, ethanol, etc,), molecular hydrogen and other useful compounds. This organism causes tetanus (lockjaw) in humans. At the tissue level, the bacterium then releases an exotoxin called tetanospasmin that causes certain nervous system irregularities by means of retrograde tramsmission through neurons to the brain. If nervous impulses cannot be checked by normal inhibitory mechanisms, it produces the generalized muscular spasms characteristic of tetanus.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012658:2525931:254229325422932543156864Clostridium botulinum Ba4 str. 657 chromosome, complete genomeanti-repressor4e-65248
NC_017179:1683199:168852816885281689337810Clostridium difficile BI1, complete genomehypothetical protein2e-61236
NC_010320:1268355:127709412770941277885792Thermoanaerobacter sp. X514 chromosome, complete genomeprophage antirepressor1e-55216
NC_015520:2974048:299950229995023000302801Mahella australiensis 50-1 BON chromosome, complete genomeprophage antirepressor3e-52205
NC_017351:643674:647068647068647856789Staphylococcus aureus subsp. aureus 11819-97 chromosome, completephage antirepressor KilAC domain protein5e-51201
NC_007622:1842000:188313418831341883922789Staphylococcus aureus RF122, complete genomephage anti-repressor protein4e-51201
NC_008525:1013979:102618110261811026984804Pediococcus pentosaceus ATCC 25745, complete genomeUncharacterized phage-encoded protein4e-51201
NC_002951:351029:358916358916359707792Staphylococcus aureus subsp. aureus COL, complete genomeprophage L54a, antirepressor, putative7e-51200
NC_007795:1922000:196176119617611962552792Staphylococcus aureus subsp. aureus NCTC 8325, complete genomebacteriophage L54a, antirepressor, putative8e-51200
NC_017208:694500:707763707763708560798Bacillus thuringiensis serovar chinensis CT-43 chromosome, completehypothetical protein1e-50199
NC_016627:4323370:436118343611834362004822Clostridium clariflavum DSM 19732 chromosome, complete genomeprophage antirepressor1e-47190
NC_012121:474144:477436477436478203768Staphylococcus carnosus subsp. carnosus TM300, complete genomeputative antirepressor, phage associated1e-47189
NC_009012:1934107:197448919744891975286798Clostridium thermocellum ATCC 27405, complete genomeBRO-like protein3e-47189
NC_015913:1248000:125915312591531259932780Candidatus Arthromitus sp. SFB-mouse-Japan, complete genomeprophage antirepressor7e-47187
NC_009782:920272:922882922882923661780Staphylococcus aureus subsp. aureus Mu3, complete genomehypothetical protein6e-46184
NC_002758:918827:921437921437922216780Staphylococcus aureus subsp. aureus Mu50, complete genomesimilar to anti-repressor6e-46184
NC_018704:176088:194458194458195210753Amphibacillus xylanus NBRC 15112, complete genomehypothetical protein2e-45182
NC_014219:830966:852587852587853432846Bacillus selenitireducens MLS10 chromosome, complete genomeprophage antirepressor6e-45181
NC_016077:1944000:194682219468221947619798Acidaminococcus intestini RyC-MR95 chromosome, complete genomeprophage antirepressor1e-43177
NC_009487:921884:925081925081925848768Staphylococcus aureus subsp. aureus JH9 chromosome, completeprophage antirepressor3e-41168
NC_009632:921759:924956924956925723768Staphylococcus aureus subsp. aureus JH1 chromosome, completeBRO domain-containing protein3e-41168
NC_015975:752927:771303771303772091789Lactobacillus ruminis ATCC 27782 chromosome, complete genomeProphage antirepressor3e-41168
NC_014554:1821320:183285618328561833608753Lactobacillus plantarum subsp. plantarum ST-III chromosome,hypothetical protein8e-41167
NC_015164:3997743:401090140109014011752852Bacteroides salanitronis DSM 18170 chromosome, complete genomeprophage antirepressor3e-37155
NC_021064:816000:817740817740818504765Propionibacterium avidum 44067, complete genomeBro family antirepressor8e-34144
NC_003212:1713958:174305217430521743819768Listeria innocua Clip11262, complete genomehypothetical protein5e-31134
NC_003212:1248000:126543812654381266205768Listeria innocua Clip11262, complete genomehypothetical protein1e-30133
NC_004116:560893:563950563950564699750Streptococcus agalactiae 2603V/R, complete genomeprophage LambdaSa1, antirepressor, putative3e-30132
NC_009706:2673906:273175627317562732508753Clostridium kluyveri DSM 555 chromosome, complete genomehypothetical protein1e-27124
NC_015164:3099097:312458831245883125337750Bacteroides salanitronis DSM 18170 chromosome, complete genomeprophage antirepressor1e-27123
NC_003909:386880:399794399794400546753Bacillus cereus ATCC 10987, complete genomephage antirepressor protein, putative3e-27122
NC_011898:3367457:340505534050553405807753Clostridium cellulolyticum H10, complete genomeAntA/AntB antirepressor domain protein3e-27122
NC_015433:1998427:200839220083922009138747Streptococcus suis ST3 chromosome, complete genomeprophage antirepressor2e-25116
NC_009513:1184000:119712311971231197926804Lactobacillus reuteri F275, complete genomephage antirepressor protein1e-22106
NC_009332:1269000:130504913050491305810762Streptococcus pyogenes str. Manfredo chromosome, complete genomephage antirepressor protein8e-21100
NC_003485:579946:582257582257583018762Streptococcus pyogenes MGAS8232, complete genomeputative antirepressor8e-21100
NC_014624:1369642:139149313914931392305813Eubacterium limosum KIST612 chromosome, complete genomeantirepressor9e-21100
NC_014393:4323368:434092443409244341685762Clostridium cellulovorans 743B chromosome, complete genomeprophage antirepressor1e-1893.6
NC_010655:1606901:163592716359271636721795Akkermansia muciniphila ATCC BAA-835, complete genomeprophage antirepressor2e-1893.2
NC_009513:870837:873859873859874632774Lactobacillus reuteri F275, complete genomeprophage antirepressor2e-1893.2
NC_010609:880196:883218883218883991774Lactobacillus reuteri JCM 1112, complete genomephage antirepressor2e-1893.2
NC_010674:2856997:287035628703562871099744Clostridium botulinum B str. Eklund 17B, complete genomeantirepressor, phage associated3e-1789
NC_004369:868890:880230880230881018789Corynebacterium efficiens YS-314, complete genomehypothetical protein4e-1788.6
NC_015052:1030708:104657610465761047355780Bifidobacterium longum subsp. infantis 157F, complete genomephage antirepressor5e-1684.7
NC_017045:99500:115403115403116116714Riemerella anatipestifer ATCC 11845 = DSM 15868 chromosome,anta/antb antirepressor domain protein2e-1583.2
NC_014738:2094000:211015421101542110867714Riemerella anatipestifer ATCC 11845 = DSM 15868 chromosome,anta/antb antirepressor domain-containing protein2e-1583.2
NC_017219:1680344:168201016820101682789780Bifidobacterium longum subsp. infantis ATCC 15697, complete genomeputative phage antirepressor5e-1581.6
NC_011593:1680215:168222016822201682999780Bifidobacterium longum subsp. infantis ATCC 15697 chromosome,phage antirepressor protein5e-1581.6
NC_014624:551510:585506585506585979474Eubacterium limosum KIST612 chromosome, complete genomehypothetical protein5e-1581.6
NC_016799:167362:181688181688182506819Corynebacterium diphtheriae 31A chromosome, complete genomeputative anti-repressor protein9e-1580.9
NC_013174:2321000:232849123284912329225735Jonesia denitrificans DSM 20603, complete genomephage antirepressor protein1e-1377
NC_003485:1061344:106346110634611064204744Streptococcus pyogenes MGAS8232, complete genomeputative antirepressor1e-1377
NC_009012:2927793:293490029349002935646747Clostridium thermocellum ATCC 27405, complete genomeBRO-like protein2e-1376.3
NC_003212:2413824:243981624398162440586771Listeria innocua Clip11262, complete genomehypothetical protein3e-1375.9
NC_014624:1840209:186105118610511861893843Eubacterium limosum KIST612 chromosome, complete genomeprophage antirepressor2e-1273.2
NC_015437:1494777:150309515030951503838744Selenomonas sputigena ATCC 35185 chromosome, complete genomeprophage antirepressor7e-1271.2
NC_004070:747146:753907753907754626720Streptococcus pyogenes MGAS315, complete genomeputative antirepressor - phage associated9e-1270.9
NC_003485:296140:298577298577299296720Streptococcus pyogenes MGAS8232, complete genomeputative antirepressor9e-1270.9
NC_004606:1107500:114213011421301142849720Streptococcus pyogenes SSI-1, complete genomeputative antirepressor (phage associated)9e-1270.9
NC_014328:303063:355534355534356307774Clostridium ljungdahlii ATCC 49587 chromosome, complete genomeputative prophage antirepressor4e-1168.9
NC_006087:2439252:245342124534212454203783Leifsonia xyli subsp. xyli str. CTCB07, complete genomeprophage antirepressor protein5e-1168.6
NC_012522:4299287:432161943216194322419801Rhodococcus opacus B4, complete genomehypothetical protein6e-1168.2
NC_003212:57061:810818108181854774Listeria innocua Clip11262, complete genomehypothetical protein6e-1168.2
NC_011001:2085986:209670520967052097502798Burkholderia cenocepacia J2315 chromosome 2, complete sequencehypothetical protein1e-1067
NC_014632:1112733:112580811258081126494687Ilyobacter polytropus DSM 2926 chromosome, complete genomephage regulatory protein, Rha family3e-1065.9
NC_014011:1139818:115821711582171158990774Aminobacterium colombiense DSM 12261 chromosome, complete genomeprophage antirepressor1e-0963.9
NC_013173:953633:978862978862979515654Desulfomicrobium baculatum DSM 4028, complete genomeprophage antirepressor3e-0962.8
NC_007434:1712000:174098017409801741699720Burkholderia pseudomallei 1710b chromosome I, complete sequenceBRO family, N-terminal domain protein6e-0961.6
NC_014836:1606587:1617241161724116188571617Desulfurispirillum indicum S5 chromosome, complete genomeBRO domain-containing protein1e-0860.5
NC_017337:1107930:111257511125751113288714Staphylococcus aureus subsp. aureus ED133 chromosome, completeprophage, antirepressor, putative2e-0860.1
NC_015660:739040:742994742994743614621Geobacillus thermoglucosidasius C56-YS93 chromosome, completeprophage antirepressor2e-0859.7
NC_007298:3764048:377102537710253771624600Dechloromonas aromatica RCB, complete genomeBRO, N-terminal3e-0859.3
NC_012658:1810640:181229818122981813038741Clostridium botulinum Ba4 str. 657 chromosome, complete genomeantirepressor, phage associated1e-0757.4
NC_004129:4333302:434864343486434349527885Pseudomonas fluorescens Pf-5, complete genomeprobable phage protein1e-0757.4
NC_017167:2298962:236904623690462369672627Alicyclobacillus acidocaldarius subsp. acidocaldarius Tc-4-1prophage antirepressor1e-0757.4
NC_004459:2443000:256512325651232565878756Vibrio vulnificus CMCP6 chromosome I, complete sequenceProphage antirepressor2e-0756.6
NC_017986:5509569:552276155227615523573813Pseudomonas putida ND6 chromosome, complete genomeBRO domain protein2e-0756.2
NC_010002:3547958:355748635574863558298813Delftia acidovorans SPH-1, complete genomeprophage antirepressor4e-0755.5
NC_002662:447236:451426451426452181756Lactococcus lactis subsp. lactis Il1403, complete genomeprophage pi1 protein 087e-0754.7
NC_002939:1866651:187870118787011879006306Geobacter sulfurreducens PCA, complete genomeBRO family protein, truncation9e-0754.3
NC_017167:1648913:168576016857601686524765Alicyclobacillus acidocaldarius subsp. acidocaldarius Tc-4-1prophage antirepressor1e-0654.3
NC_013315:1679000:167955516795551680328774Clostridium difficile CD196 chromosome, complete genomehypothetical protein2e-0653.5
NC_014721:729942:739171739171739953783Caldicellulosiruptor kristjanssonii 177R1B chromosome, completephage antirepressor protein4e-0652.4
NC_015949:1719575:174530717453071746089783Caldicellulosiruptor lactoaceticus 6A chromosome, complete genomephage antirepressor protein4e-0652.4
NC_007519:2773000:278776727877672788360594Desulfovibrio alaskensis G20 chromosome, complete genomeprophage antirepressor-like4e-0652
NC_007519:1782067:179635917963591796913555Desulfovibrio alaskensis G20 chromosome, complete genomeprophage antirepressor-like9e-0650.8