Pre_GI: BLASTP Hits

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Query: NC_004337:3621985:3638315 Shigella flexneri 2a str. 301, complete genome

Start: 3638315, End: 3639964, Length: 1650

Host Lineage: Shigella flexneri; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain was isolated in 1984 from a patient in Beijing, China. It is similar to pathogenic Escherichia coli except for the more numerous insertion sequences and contains a virulence plasmid (pCP301). Causes enteric disease. Shigella This genus is named for the Japanese scientist (Shiga) who discovered them in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. are human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, and over 1 million deaths worldwide are attributed to them. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. are extremely virulent organisms that require very few cells in order to cause disease. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. This organism, along with Shigella sonnei, is the major cause of shigellosis in industrialized countries and is responsible for endemic infections.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017328:3655876:3673171367317136748201650Shigella flexneri 2002017 chromosome, complete genomeCytoplasmic trehalase01102
NC_004337:3590323:3638315363831536399641650Shigella flexneri 2a str. 301, complete genomecytoplasmic trehalase01102
NC_004741:4132056:4133529413352941351781650Shigella flexneri 2a str. 2457T, complete genomecytoplasmic trehalase01102
NC_006905:3717306:3734137373413737357861650Salmonella enterica subsp. enterica serovar Choleraesuis strcytoplasmic trehalase0993
NC_014121:5000069:5027278502727850289271650Enterobacter cloacae subsp. cloacae ATCC 13047 chromosome, completetrehalase0959
NC_013716:1918664:1939340193934019410461707Citrobacter rodentium ICC168, complete genomeperiplasmic trehalase6e-142504
NC_007435:2701242:2728052272805227303822331Burkholderia pseudomallei 1710b chromosome II, complete sequencetrehalase3e-139495
NC_009075:937782:9642489642489661191872Burkholderia pseudomallei 668 chromosome II, complete sequencetrehalase1e-138494
NC_009078:862796:8902918902918919881698Burkholderia pseudomallei 1106a chromosome II, complete sequencetrehalase1e-138493
NC_006351:881655:9091759091759108721698Burkholderia pseudomallei K96243 chromosome 2, complete sequencetrehalase2e-138493
NC_016816:2782373:2797430279743027991151686Pantoea ananatis LMG 5342, complete genomeperiplasmic trehalase precursor TreA1e-137490
NC_010694:2189652:2189652218965221913251674Erwinia tasmaniensis, complete genomePeriplasmic trehalase1e-135484
NC_010336:1468760:1482468148246814839251458Francisella philomiragia subsp. philomiragia ATCC 25017, completeAlpha,alpha-trehalase8e-108391
NC_008601:1404933:1406119140611914075731455Francisella tularensis subsp. novicida U112, complete genometrehalase5e-99362
NC_007880:1079634:1093524109352410945701047Francisella tularensis subsp. holarctica, complete genomeTrehalase, pseuodgene6e-65248
NC_011726:1456585:1459551145955114610951545Cyanothece sp. PCC 8801, complete genomeAlpha,alpha-trehalase2e-49197
NC_014963:5034904:5040130504013050416831554Terriglobus saanensis SP1PR4 chromosome, complete genomealpha,alpha-trehalase3e-48193
NC_015311:1157679:1158684115868411600241341Prevotella denticola F0289 chromosome, complete genomealpha,alpha-trehalase1e-43178
NC_007880:1079634:109309010930901093644555Francisella tularensis subsp. holarctica, complete genomeAlpha,alpha-trehalase.2e-26120