Pre_GI: BLASTP Hits

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Query: NC_004337:3621985:3633023 Shigella flexneri 2a str. 301, complete genome

Start: 3633023, End: 3633361, Length: 339

Host Lineage: Shigella flexneri; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain was isolated in 1984 from a patient in Beijing, China. It is similar to pathogenic Escherichia coli except for the more numerous insertion sequences and contains a virulence plasmid (pCP301). Causes enteric disease. Shigella This genus is named for the Japanese scientist (Shiga) who discovered them in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. are human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, and over 1 million deaths worldwide are attributed to them. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. are extremely virulent organisms that require very few cells in order to cause disease. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. This organism, along with Shigella sonnei, is the major cause of shigellosis in industrialized countries and is responsible for endemic infections.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017328:3655876:366787936678793668217339Shigella flexneri 2002017 chromosome, complete genomeacid-resistance protein7e-62235
CP002516:246767:253990253990254328339Escherichia coli KO11, complete genomeacid-resistance protein7e-62235
NC_009800:3685651:369727736972773697615339Escherichia coli HS, complete genomeHdeB protein7e-62235
NC_009801:3956917:396777739677773968115339Escherichia coli E24377A, complete genomeHdeB protein7e-62235
NC_004337:3590323:363302336330233633361339Shigella flexneri 2a str. 301, complete genomehypothetical protein7e-62235
CP002185:3822470:385174538517453852083339Escherichia coli W, complete genomeacid-resistance protein7e-62235
AP010958:4313462:432317643231764323514339Escherichia coli O103:H2 str. 12009 DNA, complete genomeacid-resistance protein HdeB7e-62235
NC_004741:4132056:414048741404874140825339Shigella flexneri 2a str. 2457T, complete genomehypothetical protein7e-62235
NC_007384:3741708:374893137489313749269339Shigella sonnei Ss046, complete genomehypothetical protein7e-62235
NC_010658:3622610:363376936337693634107339Shigella boydii CDC 3083-94, complete genomeHdeB protein7e-62235
NC_016902:246767:253990253990254328339Escherichia coli KO11FL chromosome, complete genomeacid-resistance protein7e-62235
NC_016822:3946500:396000439600043960342339Shigella sonnei 53G, complete genomeacid-resistance protein7e-62235
NC_013364:4306000:431545543154554315793339Escherichia coli O111:H- str. 11128, complete genomeacid-resistance protein HdeB7e-62235
NC_013361:4566779:457673545767354577073339Escherichia coli O26:H11 str. 11368 chromosome, complete genomeacid-resistance protein7e-62235
NC_013353:4313462:432317643231764323514339Escherichia coli O103:H2 str. 12009, complete genomeacid-resistance protein HdeB7e-62235
NC_012947:248000:255381255381255719339Escherichia coli 'BL21-Gold(DE3)pLysS AG' chromosome, completeacid-resistance protein7e-62235
NC_007613:3470314:350153235015323501870339Shigella boydii Sb227, complete genomehypothetical protein7e-62235
NC_008258:3581583:359328435932843593610327Shigella flexneri 5 str. 8401, complete genomehypothetical protein4e-59226
NC_010473:3722571:375173437517343752060327Escherichia coli str. K-12 substr. DH10B, complete genomeacid-resistance protein4e-59226
NC_011748:3983432:402107440210744021400327Escherichia coli 55989, complete genomeacid-resistance protein4e-59226
NC_010468:231000:238363238363238689327Escherichia coli ATCC 8739, complete genomehypothetical protein4e-59226
NC_000913:3624826:365398936539893654315327Escherichia coli K12, complete genomeacid-resistance protein4e-59226
AC_000091:3976888:398412339841233984449327Escherichia coli W3110 DNA, complete genomeacid-resistance protein4e-59226
CU928145:3983432:402107440210744021400327Escherichia coli 55989 chromosome, complete genomeacid-resistance protein4e-59226
CU928160:3709081:371995137199513720277327Escherichia coli IAI1 chromosome, complete genomeacid-resistance protein4e-59226
NC_011415:3887997:390110839011083901434327Escherichia coli SE11 chromosome, complete genomeacid-resistance protein4e-59226
NC_011741:3709081:371995137199513720277327Escherichia coli IAI1 chromosome, complete genomeacid-resistance protein4e-59226
NC_012759:3529657:354248335424833542809327Escherichia coli BW2952 chromosome, complete genomeacid-resistance protein4e-59226
NC_012967:3549880:358545735854573585783327Escherichia coli B str. REL606 chromosome, complete genomeacid-resistance protein4e-59226
NC_005810:2739878:274760727476072747936330Yersinia pestis biovar Microtus str. 91001, complete genomeacid-resistance protein3e-1684
NC_006155:3456488:346751734675173467846330Yersinia pseudotuberculosis IP 32953, complete genomehypothetical protein3e-1684
NC_010465:1273000:127883412788341279163330Yersinia pseudotuberculosis YPIII, complete genomehypothetical protein3e-1684
NC_003143:2992295:300002430000243000353330Yersinia pestis CO92, complete genomehypothetical protein3e-1684
NC_008150:2681327:268905626890562689385330Yersinia pestis Antiqua, complete genomehypothetical protein3e-1684
NC_008149:1317109:132483813248381325167330Yersinia pestis Nepal516, complete genomehypothetical protein3e-1684
NC_010634:3368000:338117433811743381503330Yersinia pseudotuberculosis PB1/+, complete genomehypothetical protein3e-1684
NC_004088:1387276:139493913949391395268330Yersinia pestis KIM, complete genomehypothetical protein3e-1684
NC_010159:3779129:378482537848253785154330Yersinia pestis Angola, complete genomehypothetical protein3e-1684
NC_009381:1783886:179608617960861796415330Yersinia pestis Pestoides F chromosome, complete genomeacid-resistance protein2e-1684
NC_017265:3063016:307404430740443074373330Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,hypothetical protein3e-1684
NC_017168:2751027:276205527620552762384330Yersinia pestis A1122 chromosome, complete genomeacid-resistance protein3e-1684
NC_017160:2976683:298020929802092980538330Yersinia pestis D182038 chromosome, complete genomehypothetical protein3e-1684
NC_017154:2999841:301086930108693011198330Yersinia pestis D106004 chromosome, complete genomehypothetical protein3e-1684
NC_014029:3047506:305523530552353055564330Yersinia pestis Z176003 chromosome, complete genomehypothetical protein3e-1684
NC_009708:1284555:129045112904511290780330Yersinia pseudotuberculosis IP 31758 chromosome, complete genomeacid-resistance protein3e-1684
NC_009648:3803622:384295838429583843263306Klebsiella pneumoniae subsp. pneumoniae MGH 78578, complete genomeacid-resistance protein7e-1579.3
NC_012779:2856051:288605528860552886387333Edwardsiella ictaluri 93-146, complete genomehypothetical protein6e-1269.7