Pre_GI: BLASTP Hits

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Query: NC_004337:3621985:3628012 Shigella flexneri 2a str. 301, complete genome

Start: 3628012, End: 3628968, Length: 957

Host Lineage: Shigella flexneri; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain was isolated in 1984 from a patient in Beijing, China. It is similar to pathogenic Escherichia coli except for the more numerous insertion sequences and contains a virulence plasmid (pCP301). Causes enteric disease. Shigella This genus is named for the Japanese scientist (Shiga) who discovered them in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. are human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, and over 1 million deaths worldwide are attributed to them. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. are extremely virulent organisms that require very few cells in order to cause disease. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. This organism, along with Shigella sonnei, is the major cause of shigellosis in industrialized countries and is responsible for endemic infections.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_011741:3709081:3714883371488337158961014Escherichia coli IAI1 chromosome, complete genomehypothetical protein2e-168591
CU928160:3709081:3714883371488337158961014Escherichia coli IAI1 chromosome, complete genomeputative membrane protein2e-168591
NC_013361:4566779:4571679457167945726801002Escherichia coli O26:H11 str. 11368 chromosome, complete genomehypothetical protein3e-168591
NC_011415:3887997:3896056389605638970571002Escherichia coli SE11 chromosome, complete genomehypothetical protein3e-168591
NC_004741:4132056:414488041448804145836957Shigella flexneri 2a str. 2457T, complete genomehypothetical protein3e-168590
NC_004337:3590323:362801236280123628968957Shigella flexneri 2a str. 301, complete genomehypothetical protein3e-168590
NC_013364:4306000:430912843091284310090963Escherichia coli O111:H- str. 11128, complete genomehypothetical protein3e-168590
NC_008258:3581583:358826735882673589229963Shigella flexneri 5 str. 8401, complete genomehypothetical protein3e-168590
NC_017328:3655876:366286236628623663824963Shigella flexneri 2002017 chromosome, complete genomeputative membrane transport protein7e-168589
NC_016902:246767:2583832583832593841002Escherichia coli KO11FL chromosome, complete genomepermease2e-167588
NC_013353:4313462:4318121431812143191221002Escherichia coli O103:H2 str. 12009, complete genomehypothetical protein2e-167588
AP010958:4313462:4318121431812143191221002Escherichia coli O103:H2 str. 12009 DNA, complete genomeconserved predicted protein2e-167588
CP002516:246767:2583832583832593841002Escherichia coli KO11, complete genomepermease2e-167588
NC_009801:3956917:3962721396272139637221002Escherichia coli E24377A, complete genomeputative permease2e-167588
CP002185:3822470:3846689384668938476901002Escherichia coli W, complete genomeconserved hypothetical protein2e-167588
NC_010498:3838419:3862537386253738635381002Escherichia coli SMS-3-5, complete genomeputative permease1e-163575
CU928145:3983432:4015995401599540170201026Escherichia coli 55989 chromosome, complete genomeputative membrane protein3e-162571
NC_011748:3983432:4015995401599540170201026Escherichia coli 55989, complete genomehypothetical protein3e-162571
NC_007384:3741708:375668937566893757366678Shigella sonnei Ss046, complete genomehypothetical protein1e-124446
NC_016822:3946500:395189639518963952567672Shigella sonnei 53G, complete genomehypothetical protein6e-123440
NC_014972:1407632:1435174143517414362711098Desulfobulbus propionicus DSM 2032 chromosome, complete genomepermease2e-88326
NC_003912:1629937:162993716299371630884948Campylobacter jejuni RM1221, complete genomepermease, putative7e-46184
NC_017281:1533454:153345415334541534401948Campylobacter jejuni subsp. jejuni S3 chromosome, complete genomemembrane protein7e-46184
NC_002163:1471517:149032814903281491152825Campylobacter jejuni subsp. jejuni NCTC 11168, complete genomehypothetical protein3e-42172
NC_008554:4699577:471204947120494712951903Syntrophobacter fumaroxidans MPOB, complete genomepermease3e-42172
NC_007722:2172000:218398921839892184381393Erythrobacter litoralis HTCC2594, complete genomeputative permease2e-39162
NC_018866:108812:1320021320021331171116Dehalobacter sp. DCA chromosome, complete genomeTransporter2e-38159
NC_018867:179975:1995971995972007121116Dehalobacter sp. CF chromosome, complete genomeTransporter2e-38159
NC_019962:1909103:196271919627191963675957Natrinema pellirubrum DSM 15624, complete genomeputative permease2e-35150
NC_007907:5185510:5229711522971152307421032Desulfitobacterium hafniense Y51, complete genomehypothetical protein2e-34146
NC_017192:276187:299253299253300215963Arcobacter sp. L, complete genomehypothetical protein3e-31135
NC_018012:1789028:1802946180294618039921047Thiocystis violascens DSM 198 chromosome, complete genomeputative permease1e-27124
NC_009092:521519:5435185435185445341017Shewanella loihica PV-4, complete genomepermease2e-27123
NC_014910:2779573:2792730279273027937851056Alicycliphilus denitrificans BC chromosome, complete genomepermease3e-27122
NC_008787:1463696:146524714652471465888642Campylobacter jejuni subsp. jejuni 81-176, complete genomehypothetical protein7e-27121
NC_017059:2771085:279943327994332800398966Rhodospirillum photometricum DSM 122, complete genomePermease6e-27121
NC_014151:4021394:4043941404394140449901050Cellulomonas flavigena DSM 20109 chromosome, complete genomepermease2e-26120
NC_010730:952574:970233970233971192960Sulfurihydrogenibium sp. YO3AOP1, complete genomepermease4e-26118
NC_008781:2981868:2986274298627429873201047Polaromonas naphthalenivorans CJ2, complete genomepermease9e-26117
NC_011979:3880488:388504938850493885729681Geobacter sp. FRC-32, complete genome3e-25115
NC_014218:1689002:1689002168900216901801179Arcanobacterium haemolyticum DSM 20595 chromosome, complete genomepermease8e-25114
NC_007519:2773000:2779428277942827805191092Desulfovibrio alaskensis G20 chromosome, complete genomepermease-like protein2e-24113
NC_018604:1137797:1156011115601111570151005Brachyspira pilosicoli WesB complete genomeputative permease2e-24112
NC_014330:313813:3138133138133148171005Brachyspira pilosicoli 95/1000 chromosome, complete genomeputative permease2e-24112
NC_009714:292470:303208303208304203996Campylobacter hominis ATCC BAA-381, complete genomepermease6e-24111
NC_018607:1648607:1650167165016716511711005Brachyspira pilosicoli B2904 chromosome, complete genomepermease7e-24111
NC_016822:3946500:394943239494323949710279Shigella sonnei 53G, complete genomepermease2e-23110
NC_010816:1274702:1283050128305012840631014Bifidobacterium longum DJO10A, complete genomeHypothetical permease4e-23108
NC_015152:1230995:1246285124628512472891005Spirochaeta sp. Buddy chromosome, complete genomehypothetical protein4e-23108
NC_014972:1407632:1416751141675114178451095Desulfobulbus propionicus DSM 2032 chromosome, complete genomepermease2e-22107
NC_014376:2964731:2972321297232129733341014Clostridium saccharolyticum WM1 chromosome, complete genomepermease3e-22106
NC_007907:5297477:5309204530920453102081005Desulfitobacterium hafniense Y51, complete genomehypothetical protein6e-22105
NC_009975:688667:688667688667689623957Methanococcus maripaludis C6, complete genomepermease4e-22105
NC_015417:39633:479664796648928963Clostridium botulinum BKT015925 plasmid p1BKT015925, completepermease1e-21104
NC_011830:1288984:1316848131684813178521005Desulfitobacterium hafniense DCB-2, complete genomepermease4e-2099
NC_008751:1736512:1743434174343417445491116Desulfovibrio vulgaris subsp. vulgaris DP4, complete genomepermease8e-1994.7
NC_002937:1706000:1723708172370817248231116Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough, completepermease, putative5e-1892
NC_006510:591339:615873615873616415543Geobacillus kaustophilus HTA426, complete genomehypothetical protein3e-1789.4
NC_016593:596500:622962622962623372411Geobacillus thermoleovorans CCB_US3_UF5 chromosome, completehypothetical protein4e-1789.4
NC_010520:3526883:3538028353802835391191092Clostridium botulinum A3 str. Loch Maree, complete genomeputative permease5e-1582
NC_015850:548821:570653570653571606954Acidithiobacillus caldus SM-1 chromosome, complete genomehypothetical protein3e-1479.3
NC_014377:1985714:1990121199012119912931173Thermosediminibacter oceani DSM 16646 chromosome, complete genomepermease6e-1272
NC_014002:809816:8306588306588317011044Methanohalophilus mahii DSM 5219 chromosome, complete genomepermease9e-1167.8
NC_009486:1737703:1745017174501717461051089Thermotoga petrophila RKU-1 chromosome, complete genomepermease7e-1065.1
NC_015732:982774:9934789934789947491272Spirochaeta caldaria DSM 7334 chromosome, complete genomehypothetical protein1e-0964.3
NC_020389:714178:7323407323407333921053Methanosarcina mazei Tuc01, complete genomeTransporter1e-0964.3
NC_013939:1688400:1705751170575117069201170Deferribacter desulfuricans SSM1, complete genomehypothetical protein8e-0858.2
NC_008554:4781500:4799624479962448007151092Syntrophobacter fumaroxidans MPOB, complete genomepermease4e-0755.8
NC_013522:1538994:1542512154251215436811170Thermanaerovibrio acidaminovorans DSM 6589, complete genomepermease1e-0653.9