Pre_GI: BLASTP Hits

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Query: NC_004337:3621985:3626703 Shigella flexneri 2a str. 301, complete genome

Start: 3626703, End: 3627128, Length: 426

Host Lineage: Shigella flexneri; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain was isolated in 1984 from a patient in Beijing, China. It is similar to pathogenic Escherichia coli except for the more numerous insertion sequences and contains a virulence plasmid (pCP301). Causes enteric disease. Shigella This genus is named for the Japanese scientist (Shiga) who discovered them in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. are human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, and over 1 million deaths worldwide are attributed to them. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. are extremely virulent organisms that require very few cells in order to cause disease. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. This organism, along with Shigella sonnei, is the major cause of shigellosis in industrialized countries and is responsible for endemic infections.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017328:3655876:365995936599593660384426Shigella flexneri 2002017 chromosome, complete genomeArsenate reductase8e-78288
NC_009800:3685651:369274836927483693173426Escherichia coli HS, complete genomearsenate reductase8e-78288
NC_004741:4132056:414832041483204148745426Shigella flexneri 2a str. 2457T, complete genomearsenate reductase8e-78288
NC_010468:231000:242794242794243219426Escherichia coli ATCC 8739, complete genomearsenate reductase8e-78288
NC_010473:3722571:374600537460053746430426Escherichia coli str. K-12 substr. DH10B, complete genomearsenate reductase8e-78288
CU928160:3709081:371393337139333714358426Escherichia coli IAI1 chromosome, complete genomearsenate reductase8e-78288
NC_000913:3624826:364826036482603648685426Escherichia coli K12, complete genomearsenate reductase8e-78288
NC_004337:3590323:362670336267033627128426Shigella flexneri 2a str. 301, complete genomearsenate reductase8e-78288
NC_008258:3581583:358648935864893586914426Shigella flexneri 5 str. 8401, complete genomearsenate reductase8e-78288
NC_007613:3470314:349519734951973495622426Shigella boydii Sb227, complete genomearsenate reductase8e-78288
NC_016822:3946500:394847039484703948895426Shigella sonnei 53G, complete genomearsenate reductase8e-78288
NC_013361:4566779:457071745707174571142426Escherichia coli O26:H11 str. 11368 chromosome, complete genomearsenate reductase8e-78288
NC_012967:3549880:358092735809273581352426Escherichia coli B str. REL606 chromosome, complete genomearsenate reductase8e-78288
NC_012947:248000:259824259824260249426Escherichia coli 'BL21-Gold(DE3)pLysS AG' chromosome, completearsenate reductase8e-78288
NC_012759:3529657:353675435367543537179426Escherichia coli BW2952 chromosome, complete genomearsenate reductase8e-78288
NC_011741:3709081:371393337139333714358426Escherichia coli IAI1 chromosome, complete genomearsenate reductase8e-78288
AC_000091:3976888:398975339897533990178426Escherichia coli W3110 DNA, complete genomearsenate reductase8e-78288
CU928145:3983432:401504540150454015470426Escherichia coli 55989 chromosome, complete genomearsenate reductase3e-77286
AP010958:4313462:431716943171694317594426Escherichia coli O103:H2 str. 12009 DNA, complete genomearsenate reductase ArsC3e-77286
NC_009801:3956917:396176939617693962194426Escherichia coli E24377A, complete genomearsenate reductase3e-77286
NC_011748:3983432:401504540150454015470426Escherichia coli 55989, complete genomearsenate reductase3e-77286
NC_011415:3887997:389509438950943895519426Escherichia coli SE11 chromosome, complete genomearsenate reductase3e-77286
NC_013353:4313462:431716943171694317594426Escherichia coli O103:H2 str. 12009, complete genomearsenate reductase3e-77286
NC_013364:4306000:430812743081274308552426Escherichia coli O111:H- str. 11128, complete genomearsenate reductase8e-77285
CP002185:3822470:384571738457173846157441Escherichia coli W, complete genomearsenate reductase1e-76284
CP002516:246767:259916259916260356441Escherichia coli KO11, complete genomearsenate reductase1e-76284
NC_016902:246767:259916259916260356441Escherichia coli KO11FL chromosome, complete genomearsenate reductase1e-76284
NC_010498:3838419:386166438616643862089426Escherichia coli SMS-3-5, complete genomearsenate reductase (glutaredoxin)8e-75278
NC_010102:4557037:455760945576094558037429Salmonella enterica subsp. enterica serovar Paratyphi B str. SPB7,hypothetical protein8e-69258
NC_011094:688626:694880694880695305426Salmonella enterica subsp. enterica serovar Schwarzengrund strarsenate reductase1e-68258
NC_009425:63709:867958679587220426Enterobacter sp. 638 plasmid pENTE01, complete sequencearsenate reductase7e-68255
NC_009832:2596344:261059326105932611024432Serratia proteamaculans 568, complete genomearsenate reductase1e-62238
NC_012880:3645304:365136736513673651795429Dickeya dadantii Ech703, complete genomearsenate reductase2e-62237
NC_014500:2019113:202676220267622027193432Dickeya dadantii 3937 chromosome, complete genomearsenate reductase3e-62236
NC_011283:785973:808972808972809394423Klebsiella pneumoniae 342 chromosome, complete genomearsenate reductase2e-61234
NC_012912:2800884:281319328131932813624432Dickeya zeae Ech1591, complete genomearsenate reductase1e-60231
NC_013592:2703327:271804227180422718470429Dickeya dadantii Ech586, complete genomearsenate reductase6e-59225
NC_008577:2818546:282178728217872822263477Shewanella sp. ANA-3 chromosome 1, complete sequencearsenate reductase7e-58221
NC_010170:4800000:480888148088814809303423Bordetella petrii, complete genomearsenate reductase2e-55213
NC_009138:1974935:197873619787361979158423Herminiimonas arsenicoxydans, complete genomearsenate reductase (glutaredoxin)3e-54209
NC_010084:2484000:252751425275142527936423Burkholderia multivorans ATCC 17616 chromosome 1, completearsenate reductase5e-53205
NC_010804:996837:996837996837997259423Burkholderia multivorans ATCC 17616 chromosome 1, completearsenate reductase5e-53205
NC_014640:5047201:505571950557195056141423Achromobacter xylosoxidans A8 chromosome, complete genomearsenate reductase 22e-52203
NC_010087:376918:377633377633378055423Burkholderia multivorans ATCC 17616 chromosome 3, completearsenate reductase4e-52202
NC_015138:4103457:410416041041604104591432Acidovorax avenae subsp. avenae ATCC 19860 chromosome, completearsenate reductase1e-51201
NC_010087:376918:418155418155418577423Burkholderia multivorans ATCC 17616 chromosome 3, completearsenate reductase2e-51200
NC_010801:505000:506281506281506703423Burkholderia multivorans ATCC 17616 chromosome 3, completearsenate reductase2e-51200
NC_010410:3606826:368462536846253685125501Acinetobacter baumannii AYE, complete genomearsenate reductase (Arsenical pump modifier)3e-50196
NC_011586:268927:274722274722275156435Acinetobacter baumannii AB0057 chromosome, complete genomearsenate reductase5e-50196
NC_007952:3037590:303759030375903038012423Burkholderia xenovorans LB400 chromosome 2, complete sequenceArsenate reductase5e-50196
NC_007509:3668:502625026250684423Burkholderia sp. 383 chromosome 3, complete sequenceArsenate reductase4e-49192
NC_015186:2908387:292716429271642927586423Acidiphilium multivorum AIU301, complete genomearsenate reductase1e-46184
NC_010067:1829041:184652618465261846876351Salmonella enterica subsp. arizonae serovar 62:z4,z23:--, completehypothetical protein2e-46183
NC_009720:4367584:438903343890334389467435Xanthobacter autotrophicus Py2, complete genomearsenate reductase8e-46182
NC_008687:302450:318359318359318784426Paracoccus denitrificans PD1222 chromosome 2, complete sequencearsenate reductase2e-43174
NC_009138:467268:505182505182505610429Herminiimonas arsenicoxydans, complete genomearsenate reductase3e-43173
NC_011894:5787990:583236958323695832794426Methylobacterium nodulans ORS 2060, complete genomearsenate reductase3e-43173
NC_011894:5787990:580272058027205803145426Methylobacterium nodulans ORS 2060, complete genomearsenate reductase2e-42170
NC_010943:2422838:245209324520932452512420Stenotrophomonas maltophilia K279a, complete genomeputative arsenate reductase3e-40163
NC_011071:2207385:222099622209962221415420Stenotrophomonas maltophilia R551-3, complete genomearsenate reductase3e-39160
NC_009053:1257302:126094512609451261349405Actinobacillus pleuropneumoniae L20, complete genomearsenate reductase3e-38157
NC_011420:3822765:382848438284843828906423Rhodospirillum centenum SW, complete genomearsenate reductase, putative4e-34143
NC_017251:937786:953000953000953347348Brucella suis 1330 chromosome I, complete genomearsenate reductase ArsC2e-31134
NC_003317:1030220:103496210349621035309348Brucella melitensis 16M chromosome I, complete sequenceARSENATE REDUCTASE2e-31134
NC_004310:937800:953014953014953361348Brucella suis 1330 chromosome I, complete sequencearsenate reductase ArsC, putative2e-31134
NC_015857:963570:978782978782979129348Brucella pinnipedialis B2/94 chromosome chromosome 1, completearsenate reductase2e-31134
NC_007618:955000:969134969134969481348Brucella melitensis biovar Abortus 2308 chromosome I, completeArsenate reductase:Arsenate reductase and related2e-31134
NC_006932:956805:972014972014972361348Brucella abortus biovar 1 str. 9-941 chromosome I, completearsenate reductase ArsC, hypothetical2e-31134
NC_010742:955104:970313970313970660348Brucella abortus S19 chromosome 1, complete sequenceArsenate reductase2e-31134
NC_010169:957565:972778972778973125348Brucella suis ATCC 23445 chromosome I, complete sequencearsenate reductase2e-31134
NC_012441:956609:971822971822972169348Brucella melitensis ATCC 23457 chromosome I, complete sequencearsenate reductase2e-31134
NC_013119:942079:957292957292957639348Brucella microti CCM 4915 chromosome 1, complete sequencearsenate reductase ArsC, putative2e-31134
NC_016795:1441024:144576614457661446113348Brucella abortus A13334 chromosome 1, complete sequencearsenate reductase2e-31134
NC_016797:937753:952967952967953314348Brucella suis VBI22 chromosome I, complete sequencearsenate reductase ArsC2e-31134
NC_017244:956554:971778971778972125348Brucella melitensis M28 chromosome chromosome 1, complete sequenceArsenate reductase2e-31134
NC_017246:956868:972091972091972438348Brucella melitensis M5-90 chromosome chromosome I, completearsenate reductase2e-31134
NC_017248:953131:968211968211968558348Brucella melitensis NI chromosome chromosome I, complete sequencearsenate reductase2e-31134
NC_010103:936250:951464951464951811348Brucella canis ATCC 23365 chromosome I, complete sequencearsenate reductase6e-31132
NC_016778:96792:101533101533101880348Brucella canis HSK A52141 chromosome 1, complete sequencearsenate reductase6e-31132
NC_014733:1857020:187542018754201875776357Methylovorus sp. MP688 chromosome, complete genomearsenate reductase1e-28124
NC_016906:1565868:156783315678331568174342Gordonia polyisoprenivorans VH2 chromosome, complete genomearsenate reductase ArsC2e-23107
NC_011083:3171171:318658531865853186758174Salmonella enterica subsp. enterica serovar Heidelberg str. SL476,arsenate reductase1e-21101
NC_016613:2628843:264396426439642644314351Vibrio sp. EJY3 chromosome 1, complete sequencearsenate reductase3e-21100
NC_002516:1031386:103717210371721037525354Pseudomonas aeruginosa PAO1, complete genomeprobable arsenate reductase3e-21100
NC_017187:1305805:132243413224341322784351Arcobacter butzleri ED-1, complete genomearsenate reductase1e-1995.1
NC_010473:2839902:286162728616272861941315Escherichia coli str. K-12 substr. DH10B, complete genomeCP4-57 prophage; conserved protein5e-1992.8
AC_000091:2747520:277049627704962770810315Escherichia coli W3110 DNA, complete genomehypothetical protein5e-1992.8
NC_000913:2746886:276986227698622770176315Escherichia coli K12, complete genomeCP4-57 prophage; conserved protein5e-1992.8
NC_009075:3113393:312040631204063120762357Burkholderia pseudomallei 668 chromosome II, complete sequencearsenate reductase2e-1787.8
NC_009078:3087759:309335530933553093711357Burkholderia pseudomallei 1106a chromosome II, complete sequencearsenate reductase2e-1787.8
NC_007435:1825741:183196718319671832323357Burkholderia pseudomallei 1710b chromosome II, complete sequencearsenate reductase2e-1787.8
NC_006351:3159630:316581431658143166170357Burkholderia pseudomallei K96243 chromosome 2, complete sequencearsenate reductase2e-1787.8
NC_017100:2538461:255980525598052560086282Acetobacter pasteurianus IFO 3283-03, complete genomearsenate reductase2e-1684.3
NC_017108:2535798:255714225571422557423282Acetobacter pasteurianus IFO 3283-12, complete genomearsenate reductase2e-1684.3
NC_017111:2535000:255716025571602557441282Acetobacter pasteurianus IFO 3283-32, complete genomearsenate reductase2e-1684.3
NC_017121:2535803:255714725571472557428282Acetobacter pasteurianus IFO 3283-07, complete genomearsenate reductase2e-1684.3
NC_017125:2538441:255978525597852560066282Acetobacter pasteurianus IFO 3283-22, complete genomearsenate reductase2e-1684.3
NC_017146:2538483:255982725598272560108282Acetobacter pasteurianus IFO 3283-26, complete genomearsenate reductase2e-1684.3
NC_008835:1483237:148784614878461488202357Burkholderia mallei NCTC 10229 chromosome I, complete sequencearsenate reductase3e-1684
NC_008784:1151305:115830811583081158664357Burkholderia mallei SAVP1 chromosome I, complete sequencearsenate reductase3e-1684
NC_009079:2339756:234522423452242345580357Burkholderia mallei NCTC 10247 chromosome I, complete sequencearsenate reductase3e-1684
NC_006349:2311817:231788923178892318245357Burkholderia mallei ATCC 23344 chromosome 2, complete sequencearsenate reductase3e-1684
NC_020418:2718500:272258627225862722939354Morganella morganii subsp. morganii KT, complete genomeArsenate reductase6e-1682.8
NC_015276:2804874:280817928081792808520342Marinomonas mediterranea MMB-1 chromosome, complete genomearsenate reductase1e-1581.6
NC_008702:2259430:226688922668892267239351Azoarcus sp. BH72, complete genomearsenate reductase2e-1581.6
NC_007650:2901751:290763829076382907994357Burkholderia thailandensis E264 chromosome II, complete sequencearsenate reductase3e-1580.9
NC_017511:1812000:183457718345771834930354Neisseria gonorrhoeae TCDC-NG08107 chromosome, complete genomeprotein ArsC6e-1476.3
NC_011035:1908000:193073419307341931087354Neisseria gonorrhoeae NCCP11945 chromosome, complete genomeprotein ArsC6e-1476.3
NC_005085:786851:791756791756792106351Chromobacterium violaceum ATCC 12472, complete genomeprobable arsenate reductase (glutaredoxin)1e-1271.6
NC_010519:1684901:168584516858451686195351Haemophilus somnus 2336 chromosome, complete genomearsenate reductase5e-1269.7
NC_007333:1743890:175341417534141753851438Thermobifida fusca YX, complete genomesimilar to Arsenate reductase and related proteins glutaredoxin family1e-1065.5
NC_010677:397629:413031413031413450420Francisella tularensis subsp. mediasiatica FSC147, complete genomearsenate reductase1e-0962
NC_009749:558171:570953570953571300348Francisella tularensis subsp. holarctica FTA, complete genomearsenate reductase1e-0962
NC_007880:556334:569104569104569451348Francisella tularensis subsp. holarctica, complete genomearsenate reductase1e-0962
NC_008369:557941:572826572826573173348Francisella tularensis subsp. holarctica OSU18, complete genomearsenate reductase (glutaredoxin)1e-0962
NC_009257:386283:399073399073399420348Francisella tularensis subsp. tularensis WY96-3418 chromosome,ArsC family arsenate permease1e-0962
NC_016937:1577334:158477415847741585139366Francisella tularensis subsp. tularensis TI0902 chromosome,Arsenate reductase1e-0961.6
NC_016933:1653241:166068116606811661046366Francisella tularensis TIGB03 chromosome, complete genomeArsenate reductase1e-0961.6
NC_006570:1577491:158493115849311585296366Francisella tularensis subsp. tularensis Schu 4, complete genomearsenate reductase1e-0961.6
NC_008245:1577297:158473715847371585102366Francisella tularensis subsp. tularensis FSC 198, complete genomearsenate reductase1e-0961.6
NC_008601:1518136:152040115204011520820420Francisella tularensis subsp. novicida U112, complete genomearsenate reductase1e-0961.6
NC_010336:1335558:135195413519541352301348Francisella philomiragia subsp. philomiragia ATCC 25017, completearsenate reductase5e-0753.1