Pre_GI: BLASTP Hits

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Query: NC_004337:2478461:2482029 Shigella flexneri 2a str. 301, complete genome

Start: 2482029, End: 2482247, Length: 219

Host Lineage: Shigella flexneri; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain was isolated in 1984 from a patient in Beijing, China. It is similar to pathogenic Escherichia coli except for the more numerous insertion sequences and contains a virulence plasmid (pCP301). Causes enteric disease. Shigella This genus is named for the Japanese scientist (Shiga) who discovered them in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. are human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, and over 1 million deaths worldwide are attributed to them. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. are extremely virulent organisms that require very few cells in order to cause disease. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. This organism, along with Shigella sonnei, is the major cause of shigellosis in industrialized countries and is responsible for endemic infections.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012967:2409500:2412074241207424134111338Escherichia coli B str. REL606 chromosome, complete genomepermease DsdX5e-28122
NC_006905:3942753:3942753394275339440901338Salmonella enterica subsp. enterica serovar Choleraesuis strputative Gnt family transport protein8e-28122
NC_011742:2533500:2534747253474725360841338Escherichia coli S88 chromosome, complete genomepermease DsdX8e-28122
NC_011750:2585015:2599649259964926009861338Escherichia coli IAI39 chromosome, complete genomepermease DsdX8e-28122
NC_008563:2610499:2611652261165226129891338Escherichia coli APEC O1, complete genomeDsdX permease8e-28122
NC_007946:2625461:2639115263911526404521338Escherichia coli UTI89, complete genomehypothetical protein8e-28122
CP002797:2472908:2480464248046424818011338Escherichia coli NA114, complete genomeD-serine permease8e-28122
NC_016832:3798475:3818580381858038199171338Salmonella enterica subsp. enterica serovar Typhi str. P-stx-12,DsdX permease9e-28122
NC_003198:3824187:3844293384429338456301338Salmonella enterica subsp. enterica serovar Typhi str. CT18,DsdX permease9e-28122
NC_004631:3809678:3829783382978338311201338Salmonella enterica subsp. enterica serovar Typhi Ty2, completeDsdX permease9e-28122
NC_011274:3799696:3819796381979638211331338Salmonella enterica subsp. enterica serovar Gallinarum str. 287/91permease DsdX7e-28122
NC_016831:3779611:3800627380062738019641338Salmonella enterica subsp. enterica serovar Gallinarum/pullorumDsdX permease7e-28122
NC_012759:2342986:2361674236167423630111338Escherichia coli BW2952 chromosome, complete genomepermease DsdX5e-28122
NC_000913:2455037:2475869247586924772061338Escherichia coli K12, complete genomepredicted transporter5e-28122
NC_010473:2548946:2567634256763425689711338Escherichia coli str. K-12 substr. DH10B, complete genomepredicted transporter5e-28122
NC_009800:2505872:2509252250925225105891338Escherichia coli HS, complete genometransporter, gluconate:H+ symporter (GntP) family5e-28122
AC_000091:2462461:2483293248329324846301338Escherichia coli W3110 DNA, complete genomepredicted transporter5e-28122
NC_011750:4390000:4391185439118543925221338Escherichia coli IAI39 chromosome, complete genomepermease DsdX5e-28122
NC_011745:2751437:2752590275259027539271338Escherichia coli ED1a chromosome, complete genomepermease DsdX5e-28122
NC_010498:2555706:2568667256866725700041338Escherichia coli SMS-3-5, complete genomegluconate:H+ symporter (GntP) family protein5e-28122
NC_004431:2747237:2760235276023527615721338Escherichia coli CFT073, complete genomeDsdX permease7e-28122
NC_007384:2587876:259213425921342592352219Shigella sonnei Ss046, complete genomeD-serine permease3e-26117
NC_011748:2708500:271134727113472711565219Escherichia coli 55989, complete genome3e-26117
NC_004741:2456297:246016824601682460386219Shigella flexneri 2a str. 2457T, complete genome3e-26117
AP010958:2911741:292996329299632930181219Escherichia coli O103:H2 str. 12009 DNA, complete genome3e-26117
NC_007606:2353098:235577723557772355995219Shigella dysenteriae Sd197, complete genomeD-serine permease3e-26117
CU928160:2513000:251583625158362516054219Escherichia coli IAI1 chromosome, complete genomefragment of putative transporter (partial)3e-26117
CP002185:2659628:266342526634252663643219Escherichia coli W, complete genome3e-26117
CU928145:2708500:271134727113472711565219Escherichia coli 55989 chromosome, complete genomefragment of putative transporter (partial)3e-26117
NC_009801:2639787:264247526424752642693219Escherichia coli E24377A, complete genomehypothetical protein3e-26117
NC_011353:3276734:331121933112193311437219Escherichia coli O157:H7 str. EC4115 chromosome, complete genomehypothetical protein3e-26117
NC_017328:2516000:251967125196712519889219Shigella flexneri 2002017 chromosome, complete genomeDsdX permease3e-26117
NC_016822:2678691:268294926829492683167219Shigella sonnei 53G, complete genomepermease DsdX3e-26117
NC_013941:2928000:294816929481692948387219Escherichia coli O55:H7 str. CB9615 chromosome, complete genomehypothetical protein3e-26117
NC_013361:3313284:333712833371283337346219Escherichia coli O26:H11 str. 11368 chromosome, complete genome3e-26117
NC_013353:2911741:292996329299632930181219Escherichia coli O103:H2 str. 12009, complete genome3e-26117
NC_011741:2513000:251583625158362516054219Escherichia coli IAI1 chromosome, complete genome3e-26117
NC_011601:2614691:263538426353842635602219Escherichia coli O127:H6 str. E2348/69 chromosome, complete genome3e-26117
NC_011415:2732000:274707427470742747292219Escherichia coli SE11 chromosome, complete genomehypothetical protein3e-26117
NC_008253:2499735:250240125024012502619219Escherichia coli 536, complete genometruncated DsdX permease4e-26116
NC_008258:2473000:247576824757682475986219Shigella flexneri 5 str. 8401, complete genomeD-serine permease8e-26115
NC_013008:3231414:326609032660903266305216Escherichia coli O157:H7 str. TW14359 chromosome, complete genome7e-26115
NC_002655:3260500:327706232770623277280219Escherichia coli O157:H7 EDL933, complete genomeD-serine permease2e-25114
NC_011751:2768864:277155227715522771770219Escherichia coli UMN026 chromosome, complete genome3e-25113
NC_009901:4216206:4217550421755042188871338Shewanella pealeana ATCC 700345, complete genomegluconate transporter2e-1890.9