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Query: NC_004088:3859173:3884989 Yersinia pestis KIM, complete genome

Start: 3884989, End: 3886536, Length: 1548

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017265:3724500:3750349375034937518961548Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,Fe-S Oxidoreductase01023
NC_017168:341233:3677593677593693061548Yersinia pestis A1122 chromosome, complete genomehypothetical protein01023
NC_015224:3820338:3858239385823938605422304Yersinia enterocolitica subsp. palearctica 105.5R(r) chromosome,hypothetical protein0996
NC_015424:3277292:3292064329206432944152352Aeromonas veronii B565 chromosome, complete genomeputative Fe-S oxidoreductase0815
NC_013851:3166969:3191505319150531936162112Allochromatium vinosum DSM 180 chromosome, complete genomeRadical SAM domain protein2e-180632
NC_010611:208268:2280062280062303842379Acinetobacter baumannii ACICU, complete genomeFe-S oxidoreductase7e-179627
NC_010410:3719599:3719599371959937219772379Acinetobacter baumannii AYE, complete genomehypothetical protein5e-179627
NC_005085:1870890:1886774188677418890502277Chromobacterium violaceum ATCC 12472, complete genomeprobable Fe-S oxidoreductase family 22e-176619
NC_019940:1:3539353956712133Thioflavicoccus mobilis 8321 chromosome, complete genomeradical SAM protein YgiQ4e-176617
NC_017075:4153128:4168058416805841704962439Rubrivivax gelatinosus IL144, complete genomeradical SAM domain-containing protein1e-174613
NC_008782:3167440:3208859320885932100851227Acidovorax sp. JS42, complete genomeRadical SAM N-terminal domain protein5e-126451
NC_019892:2816549:2821245282124528233052061Singulisphaera acidiphila DSM 18658 chromosome, complete genomeradical SAM protein YgiQ6e-125447
NC_009483:1253077:1253077125307712548941818Geobacter uraniireducens Rf4 chromosome, complete genomeradical SAM domain-containing protein1e-117424
NC_009464:180335:1978751978751996741800Uncultured methanogenic archaeon RC-I, complete genomehypothetical protein5e-117421
NC_014033:896120:9179869179869199982013Prevotella ruminicola 23 chromosome, complete genomehypothetical protein7e-111401
NC_007907:2249607:2269176226917622711041929Desulfitobacterium hafniense Y51, complete genomehypothetical protein6e-102371
NC_015578:3694813:3715934371593437177751842Treponema primitia ZAS-2 chromosome, complete genomeradical SAM N- domain-containing protein9e-102371
NC_014721:1028841:1032612103261210344801869Caldicellulosiruptor kristjanssonii 177R1B chromosome, completeradical sam domain protein5e-99362
NC_014652:1758787:1775002177500217768701869Caldicellulosiruptor hydrothermalis 108 chromosome, completeradical sam domain protein2e-98360
NC_015732:191554:2026422026422045911950Spirochaeta caldaria DSM 7334 chromosome, complete genomehypothetical protein1e-96354
NC_014314:576465:6470086470086488581851Dehalogenimonas lykanthroporepellens BL-DC-9 chromosome, completeradical SAM domain-containing protein1e-95350
NC_017187:719206:7405147405147422711758Arcobacter butzleri ED-1, complete genomeradical SAM domain-containing protein1e-87324
NC_014166:1077121:1100291110029111020211731Arcobacter nitrofigilis DSM 7299 chromosome, complete genomeradical SAM domain-containing protein4e-84312
NC_010337:2339056:2356087235608723571061020Heliobacterium modesticaldum Ice1, complete genomeradical sam protein, putative6e-83308