Pre_GI: BLASTP Hits

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Query: NC_004088:3859173:3884192 Yersinia pestis KIM, complete genome

Start: 3884192, End: 3885004, Length: 813

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017265:3724500:374955237495523750364813Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,hypothetical protein3e-135480
NC_017168:341233:366962366962367774813Yersinia pestis A1122 chromosome, complete genomehypothetical protein3e-135480
NC_015224:3820338:3858239385823938605422304Yersinia enterocolitica subsp. palearctica 105.5R(r) chromosome,hypothetical protein4e-110397
NC_015424:3277292:3292064329206432944152352Aeromonas veronii B565 chromosome, complete genomeputative Fe-S oxidoreductase3e-75281
NC_010410:3719599:3719599371959937219772379Acinetobacter baumannii AYE, complete genomehypothetical protein4e-67254
NC_010611:208268:2280062280062303842379Acinetobacter baumannii ACICU, complete genomeFe-S oxidoreductase4e-67254
NC_013851:3166969:3191505319150531936162112Allochromatium vinosum DSM 180 chromosome, complete genomeRadical SAM domain protein1e-63243
NC_017075:4153128:4168058416805841704962439Rubrivivax gelatinosus IL144, complete genomeradical SAM domain-containing protein2e-62239
NC_005085:1870890:1886774188677418890502277Chromobacterium violaceum ATCC 12472, complete genomeprobable Fe-S oxidoreductase family 24e-61234
NC_019940:1:3539353956712133Thioflavicoccus mobilis 8321 chromosome, complete genomeradical SAM protein YgiQ1e-57223
NC_019892:2816549:2821245282124528233052061Singulisphaera acidiphila DSM 18658 chromosome, complete genomeradical SAM protein YgiQ8e-36150
NC_015732:191554:2026422026422045911950Spirochaeta caldaria DSM 7334 chromosome, complete genomehypothetical protein5e-35148
NC_009464:180335:1978751978751996741800Uncultured methanogenic archaeon RC-I, complete genomehypothetical protein1e-33143
NC_015578:3694813:3715934371593437177751842Treponema primitia ZAS-2 chromosome, complete genomeradical SAM N- domain-containing protein3e-32139
NC_014652:1758787:1775002177500217768701869Caldicellulosiruptor hydrothermalis 108 chromosome, completeradical sam domain protein6e-31134
NC_014721:1028841:1032612103261210344801869Caldicellulosiruptor kristjanssonii 177R1B chromosome, completeradical sam domain protein6e-30131
NC_009483:1253077:1253077125307712548941818Geobacter uraniireducens Rf4 chromosome, complete genomeradical SAM domain-containing protein1e-28127
NC_007907:2249607:2269176226917622711041929Desulfitobacterium hafniense Y51, complete genomehypothetical protein4e-28125
NC_014033:896120:9179869179869199982013Prevotella ruminicola 23 chromosome, complete genomehypothetical protein2e-23109
NC_014314:576465:6470086470086488581851Dehalogenimonas lykanthroporepellens BL-DC-9 chromosome, completeradical SAM domain-containing protein2e-1996.7
NC_014166:1077121:1100291110029111020211731Arcobacter nitrofigilis DSM 7299 chromosome, complete genomeradical SAM domain-containing protein3e-1789.4
NC_017187:719206:7405147405147422711758Arcobacter butzleri ED-1, complete genomeradical SAM domain-containing protein6e-1684.7