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Query: NC_004088:3859173:3874708 Yersinia pestis KIM, complete genome

Start: 3874708, End: 3876264, Length: 1557

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017265:3724500:3740068374006837416241557Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,putative fimbrial anchor01067
NC_003143:741169:7462687462687478241557Yersinia pestis CO92, complete genomehypothetical protein01067
NC_008149:650706:6558056558056573611557Yersinia pestis Nepal516, complete genomemembrane protein01067
NC_010159:259695:2752302752302767861557Yersinia pestis Angola, complete genomehypothetical protein01067
NC_005810:3333000:3338210333821033397661557Yersinia pestis biovar Microtus str. 91001, complete genomehypothetical protein01067
NC_008150:3430000:3445590344559034471461557Yersinia pestis Antiqua, complete genomehypothetical protein01067
NC_014029:792719:7978127978127993681557Yersinia pestis Z176003 chromosome, complete genomehypothetical protein01067
NC_017160:737000:7421537421537437091557Yersinia pestis D182038 chromosome, complete genomehypothetical protein01067
NC_017168:341233:3574783574783590341557Yersinia pestis A1122 chromosome, complete genomehypothetical protein01067
NC_006155:3992818:4013489401348940150451557Yersinia pseudotuberculosis IP 32953, complete genomeputative membrane protein.01061
NC_010634:3905369:3924946392494639265021557Yersinia pseudotuberculosis PB1/+, complete genomehypothetical protein01060
NC_009708:692508:6976616976616992171557Yersinia pseudotuberculosis IP 31758 chromosome, complete genomehypothetical protein01059
NC_009381:522731:5278305278305293711542Yersinia pestis Pestoides F chromosome, complete genomehypothetical protein01057
NC_017154:734875:7399747399747414521479Yersinia pestis D106004 chromosome, complete genomemembrane protein01015
NC_015224:3820338:3849419384941938507921374Yersinia enterocolitica subsp. palearctica 105.5R(r) chromosome,putative tight adherance operon protein3e-52206
NC_008800:3955284:3971157397115739725361380Yersinia enterocolitica subsp. enterocolitica 8081 chromosome,putative tight adherance operon protein4e-50199
NC_012913:167034:1712931712931730711779Aggregatibacter aphrophilus NJ8700, complete genomeTadG2e-1894.4
NC_016513:974402:9820879820879837271641Aggregatibacter actinomycetemcomitans ANH9381 chromosome, completeFlp pilus assembly protein TadG2e-1067.8
NC_013716:4306695:4380064438006443820071944Citrobacter rodentium ICC168, complete genomeputative tight adherence protein TadG4e-1067
NC_013416:668152:6758316758316774681638Aggregatibacter actinomycetemcomitans D11S-1, complete genomeTadG7e-0962.8
NC_014966:638355:6570056570056583331329Vibrio vulnificus MO6-24/O chromosome II, complete sequenceprotein TadG, associated with Flp pilus assembly4e-0757
NC_005140:660305:6790276790276803551329Vibrio vulnificus YJ016 chromosome II, complete sequencehypothetical protein1e-0655.1
NC_004460:81687:1004551004551017351281Vibrio vulnificus CMCP6 chromosome II, complete sequenceFlp pilus assembly protein TadG1e-0655.1