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Query: NC_004088:3859173:3860464 Yersinia pestis KIM, complete genome

Start: 3860464, End: 3861570, Length: 1107

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017265:3724500:3725824372582437269301107Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,Fimbrial protein0694
NC_017168:341233:3425243425243436301107Yersinia pestis A1122 chromosome, complete genomeFimbrial protein0694
NC_017160:737000:7575587575587586641107Yersinia pestis D182038 chromosome, complete genomeFimbrial protein0694
NC_014029:792719:8132178132178143231107Yersinia pestis Z176003 chromosome, complete genomeFimbrial protein0694
NC_008149:650706:6704996704996716051107Yersinia pestis Nepal516, complete genomeFimbrial protein0694
NC_010159:259695:2609862609862620921107Yersinia pestis Angola, complete genomefimbrial family protein0694
NC_008150:3430000:3431346343134634324521107Yersinia pestis Antiqua, complete genomeFimbrial protein0694
NC_005810:3333000:3352901335290133540071107Yersinia pestis biovar Microtus str. 91001, complete genomefimbrial protein0694
NC_003143:741169:7616727616727627781107Yersinia pestis CO92, complete genomeFimbrial protein0694
NC_010465:733916:7591757591757602781104Yersinia pseudotuberculosis YPIII, complete genomeFimbrial protein0676
NC_006155:3992818:3992818399281839939211104Yersinia pseudotuberculosis IP 32953, complete genomeFimbrial protein0675
NC_009381:522731:542834542834543628795Yersinia pestis Pestoides F chromosome, complete genome3e-149528
NC_009381:522731:542523542523542864342Yersinia pestis Pestoides F chromosome, complete genome3e-40166
NC_010552:196457:2073512073512083611011Burkholderia ambifaria MC40-6 chromosome 2, complete sequenceFimbrial protein8e-1375.1
NC_010552:196457:199536199536199940405Burkholderia ambifaria MC40-6 chromosome 2, complete sequenceFimbrial protein4e-1272.4
NC_010552:196457:208701208701209690990Burkholderia ambifaria MC40-6 chromosome 2, complete sequenceFimbrial protein3e-1170.1
NC_007946:4779745:4801952480195248030311080Escherichia coli UTI89, complete genomeputative F17-like fimbril adhesin subunit1e-0860.8
NC_008253:3941938:3960709396070939617881080Escherichia coli 536, complete genomeputative F17-like fimbril adhesin subunit1e-0860.8
NC_008321:2649781:267624526762452677228984Shewanella sp. MR-4, complete genomeFimbrial protein3e-0653.1