Pre_GI: BLASTP Hits

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Query: NC_004088:3689000:3721401 Yersinia pestis KIM, complete genome

Start: 3721401, End: 3722777, Length: 1377

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017160:905783:9104179104179117931377Yersinia pestis D182038 chromosome, complete genomehypothetical protein0922
NC_005810:3917254:3924567392456739259431377Yersinia pestis biovar Microtus str. 91001, complete genomehypothetical protein0922
NC_009381:588137:5927715927715941291359Yersinia pestis Pestoides F chromosome, complete genomehypothetical protein0902
NC_014310:1750817:1759985175998517613431359Ralstonia solanacearum PSI07 megaplasmid, complete sequencehypothetical protein3e-169595
NC_006347:4961865:497226549722654973038774Bacteroides fragilis YCH46, complete genomehypothetical protein6e-0962.8
NC_017168:3286:1059910599119751377Yersinia pestis A1122 chromosome, complete genomehypothetical protein0922
NC_003143:1059580:1093299109329910946751377Yersinia pestis CO92, complete genomehypothetical protein0922
NC_009708:874770:8794198794198807771359Yersinia pseudotuberculosis IP 31758 chromosome, complete genomehypothetical protein0902
NC_010634:3720214:3752451375245137538091359Yersinia pseudotuberculosis PB1/+, complete genomehypothetical protein0900
NC_006677:2402282:2425203242520324266901488Gluconobacter oxydans 621H, complete genomehypothetical protein5e-2099.4
NC_017265:809943:8145778145778159531377Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,hypothetical protein0922
NC_014029:961522:9661569661569675321377Yersinia pestis Z176003 chromosome, complete genomehypothetical protein0922
NC_008150:317903:3234713234713248471377Yersinia pestis Antiqua, complete genomehypothetical protein0922
NC_010465:893921:8985568985568999141359Yersinia pseudotuberculosis YPIII, complete genomehypothetical protein0902
NC_016582:1751988:1751988175198817533671380Streptomyces bingchenggensis BCW-1 chromosome, complete genomehypothetical protein2e-23110
NC_016776:4982094:499249649924964993269774Bacteroides fragilis 638R, complete genomehypothetical protein8e-0962.4
NC_017154:902739:9083089083089096841377Yersinia pestis D106004 chromosome, complete genomehypothetical protein0922
NC_008149:3556999:3589273358927335906491377Yersinia pestis Nepal516, complete genomehypothetical protein0922
NC_006155:3805640:3839379383937938407371359Yersinia pseudotuberculosis IP 32953, complete genomehypothetical protein0902
NC_014840:205723:2057232057232071921470Pantoea sp. At-9b plasmid pPAT9B03, complete sequencehypothetical protein1e-24114
NC_003228:4895326:490572549057254906498774Bacteroides fragilis NCTC 9343, complete genomehypothetical protein6e-0962.8
NC_019897:763412:7812337812337834822250Thermobacillus composti KWC4 chromosome, complete genomepeptidase7e-1065.9
NC_016609:4834378:4885533488553348866391107Niastella koreensis GR20-10 chromosome, complete genomepeptidase-like protein9e-0755.5
NC_013416:16493:2406624066254061341Aggregatibacter actinomycetemcomitans D11S-1, complete genomephospholipase/carboxylesterase4e-1169.7
NC_018607:1251357:1255387125538712567631377Brachyspira pilosicoli B2904 chromosome, complete genomephospholipase/carboxylesterase2e-0757
NC_013132:8732093:875596687559668756796831Chitinophaga pinensis DSM 2588, complete genomephospholipase/Carboxylesterase2e-0757.4
NC_013406:3672857:368446036844603685125666Paenibacillus sp. Y412MC10 chromosome, complete genomephospholipase/carboxylesterase5e-1066.2
NC_016513:317197:3263843263843277241341Aggregatibacter actinomycetemcomitans ANH9381 chromosome, completephospholipase/carboxylesterase8e-1168.9