Pre_GI: BLASTP Hits

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Query: NC_004088:3689000:3699323 Yersinia pestis KIM, complete genome

Start: 3699323, End: 3699445, Length: 123

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_005810:3917254:394775139477513948029279Yersinia pestis biovar Microtus str. 91001, complete genomeinsertion sequence protein8e-1682.4
NC_006155:3805640:381232038123203812595276Yersinia pseudotuberculosis IP 32953, complete genomeInsertion sequence protein9e-1682.4
NC_008149:3556999:356714935671493567424276Yersinia pestis Nepal516, complete genomeinsertion sequence protein8e-1682.4
NC_008150:317903:346640346640346915276Yersinia pestis Antiqua, complete genomeinsertion sequence protein8e-1682.4
NC_003143:1059580:107124510712451071520276Yersinia pestis CO92, complete genomeinsertion sequence protein8e-1682.4
NC_017168:3286:337543375434029276Yersinia pestis A1122 chromosome, complete genomeinsertion sequence protein8e-1682.4
NC_017265:809943:837771837771838046276Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,insertion sequence protein8e-1682.4
NC_008149:3556999:356215535621553562430276Yersinia pestis Nepal516, complete genomeinsertion sequence protein1e-1582
NC_003143:1059580:106625110662511066526276Yersinia pestis CO92, complete genomeinsertion sequence protein1e-1582
NC_010634:3720214:372537137253713725646276Yersinia pseudotuberculosis PB1/+, complete genomeinsertion element protein1e-1582
NC_009708:874770:902342902342902617276Yersinia pseudotuberculosis IP 31758 chromosome, complete genomeIS1 family transposase orfA1e-1582
NC_009708:874770:907446907446907721276Yersinia pseudotuberculosis IP 31758 chromosome, complete genomeIS1 family transposase orfA1e-1582
NC_017168:3286:387483874839023276Yersinia pestis A1122 chromosome, complete genomeinsertion sequence protein1e-1582
NC_004088:3689000:369432936943293694607279Yersinia pestis KIM, complete genometransposase1e-1582
NC_006155:3805640:381731438173143817589276Yersinia pseudotuberculosis IP 32953, complete genomeInsertion sequence protein.4e-1580.1
NC_010634:3720214:373036637303663730641276Yersinia pseudotuberculosis PB1/+, complete genomeinsertion element protein4e-1580.1
NC_010159:172469:172891172891173013123Yersinia pestis Angola, complete genomeIS1 family transposase orfA3e-1580.1
NC_013421:701005:708322708322708594273Pectobacterium wasabiae WPP163, complete genomeInsertion element protein7e-0959.3
NC_013421:478586:484740484740485012273Pectobacterium wasabiae WPP163, complete genomeInsertion element protein7e-0959.3
NC_009790:42112:431894318943461273Escherichia coli E24377A plasmid pETEC_74, complete sequenceIS1, transposase orfA8e-0855.8
NC_014228:1712339:174564217456421746040399Xenorhabdus nematophila ATCC 19061, complete genomeInsertion element IS1 1/2/3/5/6 protein insA (IS1a/IS1b/IS1c/IS1d) (modular protein)1e-0755.1
NC_014228:1929665:197630819763081976703396Xenorhabdus nematophila ATCC 19061, complete genomeInsertion element IS1 1/2/3/5/6 protein insA (IS1a/IS1b/IS1c/IS1d) (modular protein)1e-0755.1
NC_007607:87000:105382105382105654273Shigella dysenteriae Sd197 plasmid pSD1_197, complete sequenceiso-IS1 ORF12e-0754.3
NC_013892:1503162:154240215424021542677276Xenorhabdus bovienii SS-2004 chromosome, complete genomeinsertion element protein3e-0753.9
NC_013892:1890500:197614219761421976417276Xenorhabdus bovienii SS-2004 chromosome, complete genomeinsertion element iso-IS1N protein insA3e-0753.9
NC_013892:2108175:216042121604212160696276Xenorhabdus bovienii SS-2004 chromosome, complete genomeinsertion element iso-IS1N protein insA3e-0753.9
NC_013892:3278647:328058832805883280863276Xenorhabdus bovienii SS-2004 chromosome, complete genomeinsertion element iso-IS1N protein insA3e-0753.9
NC_013892:3278647:331751733175173317792276Xenorhabdus bovienii SS-2004 chromosome, complete genomeinsertion element iso-IS1N protein insA3e-0753.9
NC_013892:3278647:331981233198123320087276Xenorhabdus bovienii SS-2004 chromosome, complete genomeinsertion element iso-IS1N protein insA3e-0753.9
NC_013892:3745749:376905437690543769329276Xenorhabdus bovienii SS-2004 chromosome, complete genomeinsertion element iso-IS1N protein insA3e-0753.9
NC_013892:853366:875825875825876100276Xenorhabdus bovienii SS-2004 chromosome, complete genomeinsertion element iso-IS1N protein insA3e-0753.9
NC_004741:2526421:253896725389672539239273Shigella flexneri 2a str. 2457T, complete genomeIS1N orfA4e-0753.5
NC_012779:2856051:287188728718872872108222Edwardsiella ictaluri 93-146, complete genomeIS1-family insertion element protein5e-0753.1
NC_013892:274297:300625300625300780156Xenorhabdus bovienii SS-2004 chromosome, complete genomeinsertion element iso-IS1N protein insA (fragment)5e-0753.1
NC_013892:853366:875192875192875347156Xenorhabdus bovienii SS-2004 chromosome, complete genomeinsertion element iso-IS1N protein insA (fragment)5e-0753.1
NC_004851:157675:172967172967173239273Shigella flexneri 2a str. 301 plasmid pCP301, complete sequenceiso-IS1 ORF16e-0752.8
NC_011742:4655373:467218546721854672457273Escherichia coli S88 chromosome, complete genometransposase InsA (ORF1) IS11e-0652.4
NC_008563:4739333:475752347575234757795273Escherichia coli APEC O1, complete genomeIS1 InsA protein1e-0652.4
NC_004431:4270305:428996842899684290240273Escherichia coli CFT073, complete genomeInsertion element IS1 1/2/3/5/6 protein insA1e-0652.4
NC_006625:1:847084708742273Klebsiella pneumoniae NTUH-K2044 plasmid pK2044, complete sequenceiso-IS1 ORF12e-0650.8