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Query: NC_004088:3689000:3694700 Yersinia pestis KIM, complete genome

Start: 3694700, End: 3695467, Length: 768

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017265:809943:841902841902842669768Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,hypothetical protein1e-133475
NC_008149:3556999:356252635625263563293768Yersinia pestis Nepal516, complete genomehypothetical protein1e-133475
NC_010159:172469:173262173262174029768Yersinia pestis Angola, complete genomehypothetical protein1e-133475
NC_008150:317903:350771350771351538768Yersinia pestis Antiqua, complete genomehypothetical protein1e-133475
NC_006155:3805640:381269138126913813458768Yersinia pseudotuberculosis IP 32953, complete genomehypothetical protein1e-133475
NC_005810:3917254:395188539518853952652768Yersinia pestis biovar Microtus str. 91001, complete genomehypothetical protein1e-133475
NC_009708:874770:906583906583907350768Yersinia pseudotuberculosis IP 31758 chromosome, complete genomehypothetical protein1e-133475
NC_017160:1628500:166255516625551663322768Yersinia pestis D182038 chromosome, complete genomehypothetical protein1e-133475
NC_017168:3286:378853788538652768Yersinia pestis A1122 chromosome, complete genomehypothetical protein1e-133475
NC_010634:3720214:372574237257423726509768Yersinia pseudotuberculosis PB1/+, complete genomehypothetical protein3e-133474
NC_003143:1059580:106662210666221067371750Yersinia pestis CO92, complete genomehypothetical protein3e-130464
NC_009648:1487692:149973414997341500501768Klebsiella pneumoniae subsp. pneumoniae MGH 78578, complete genomehypothetical protein3e-40165
NC_005810:1467772:149936414993641500137774Yersinia pestis biovar Microtus str. 91001, complete genomehypothetical protein6e-1891.3
NC_008150:844727:884323884323885096774Yersinia pestis Antiqua, complete genomehypothetical protein6e-1891.3
NC_004088:2966331:297640329764032977176774Yersinia pestis KIM, complete genomehypothetical protein6e-1891.3
NC_003143:1630000:167045916704591671232774Yersinia pestis CO92, complete genomehypothetical protein6e-1891.3
NC_009381:1682000:169373316937331694506774Yersinia pestis Pestoides F chromosome, complete genomehypothetical protein6e-1891.3
NC_009708:2788855:283016828301682830941774Yersinia pseudotuberculosis IP 31758 chromosome, complete genomehypothetical protein6e-1891.3
NC_014029:1702338:174496417449641745737774Yersinia pestis Z176003 chromosome, complete genomehypothetical protein6e-1891.3
NC_017154:1644404:168705716870571687830774Yersinia pestis D106004 chromosome, complete genomehypothetical protein6e-1891.3
NC_017160:1628500:166767116676711668444774Yersinia pestis D182038 chromosome, complete genomehypothetical protein6e-1891.3
NC_017168:3977767:398783939878393988612774Yersinia pestis A1122 chromosome, complete genomehypothetical protein6e-1891.3
NC_017265:2586729:259680125968012597574774Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,hypothetical protein6e-1891.3
NC_008149:2802392:281246428124642813237774Yersinia pestis Nepal516, complete genomehypothetical protein6e-1891.3