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Query: NC_004088:3661601:3677270 Yersinia pestis KIM, complete genome

Start: 3677270, End: 3677596, Length: 327

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017265:854492:859773859773860099327Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,hypothetical protein1e-57221
NC_010634:3692321:370799737079973708323327Yersinia pseudotuberculosis PB1/+, complete genomehypothetical protein1e-57221
NC_010159:138879:155868155868156194327Yersinia pestis Angola, complete genomehypothetical protein1e-57221
NC_008149:3529428:354509635450963545422327Yersinia pestis Nepal516, complete genomehypothetical protein1e-57221
NC_005810:3964468:396974939697493970075327Yersinia pestis biovar Microtus str. 91001, complete genomehypothetical protein1e-57221
NC_008150:361224:368624368624368950327Yersinia pestis Antiqua, complete genomehypothetical protein1e-57221
NC_003143:1033500:104919210491921049518327Yersinia pestis CO92, complete genomehypothetical protein1e-57221
NC_006155:3779381:379501537950153795341327Yersinia pseudotuberculosis IP 32953, complete genomehypothetical protein1e-57221
NC_010465:933488:938862938862939188327Yersinia pseudotuberculosis YPIII, complete genomeprotein of unknown function DUF4691e-57221
NC_009381:627685:632965632965633291327Yersinia pestis Pestoides F chromosome, complete genomehypothetical protein1e-57221
NC_009708:986918:992398992398992724327Yersinia pseudotuberculosis IP 31758 chromosome, complete genomehypothetical protein1e-57221
NC_014029:1001000:100633810063381006664327Yersinia pestis Z176003 chromosome, complete genomehypothetical protein1e-57221
NC_017154:941065:948483948483948809327Yersinia pestis D106004 chromosome, complete genomehypothetical protein1e-57221
NC_017160:945176:950456950456950782327Yersinia pestis D182038 chromosome, complete genomehypothetical protein1e-57221
NC_017168:50391:557565575656082327Yersinia pestis A1122 chromosome, complete genomehypothetical protein1e-57221
NC_017047:3907854:390897339089733909299327Rahnella aquatilis HX2 chromosome, complete genomehypothetical protein1e-43174
NC_015061:3840463:384158238415823841908327Rahnella sp. Y9602 chromosome, complete genomehypothetical protein1e-43174
NC_016818:3851542:385330538533053853631327Rahnella aquatilis CIP 78.65 = ATCC 33071 chromosome, completehypothetical protein1e-42171
NC_013592:956829:987474987474987818345Dickeya dadantii Ech586, complete genomeprotein of unknown function DUF4693e-42170
NC_012779:261438:279737279737280063327Edwardsiella ictaluri 93-146, complete genomehypothetical protein8e-40162
NC_020418:1397112:142172914217291422055327Morganella morganii subsp. morganii KT, complete genomePutative protein YggL1e-39161
NC_013508:275081:296711296711297037327Edwardsiella tarda EIB202, complete genomehypothetical protein2e-39160
NC_004578:2560473:256479425647942565138345Pseudomonas syringae pv. tomato str. DC3000, complete genomehypothetical protein2e-1994.7
NC_010322:1817598:182171518217151822059345Pseudomonas putida GB-1 chromosome, complete genomehypothetical protein1e-1892
NC_010084:1054000:107159010715901071925336Burkholderia multivorans ATCC 17616 chromosome 1, completehypothetical protein6e-1062.8
NC_011992:1912200:191559519155951915933339Acidovorax ebreus TPSY, complete genomeprotein of unknown function DUF4697e-0856.2
NC_007974:785216:798109798109798459351Ralstonia metallidurans CH34 chromosome 2, complete sequenceprotein of unknown function DUF4691e-0651.6