Pre_GI: BLASTP Hits

Some Help

Query: NC_004088:3661601:3665557 Yersinia pestis KIM, complete genome

Start: 3665557, End: 3674889, Length: 9333

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




Search Results with any or all of these Fields

Host Accession, e.g. NC_0123..Host Description, e.g. Clostri...
Host Lineage, e.g. archae, Proteo, Firmi...
Host Information, e.g. soil, Thermo, Russia



SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017168:50391:5846358463677959333Yersinia pestis A1122 chromosome, complete genomeputative virulence determinant06110
NC_017160:945176:9531659531659624979333Yersinia pestis D182038 chromosome, complete genomeputative virulence determinant06110
NC_014029:1001000:1009046100904610183789333Yersinia pestis Z176003 chromosome, complete genomeputative virulence determinant06110
NC_003143:1033500:1037479103747910468119333Yersinia pestis CO92, complete genomeputative virulence determinant06110
NC_008150:361224:3713313713313806639333Yersinia pestis Antiqua, complete genomeputative virulence determinant06110
NC_008149:3529428:3533384353338435427169333Yersinia pestis Nepal516, complete genomevirulence determinant06110
NC_005810:3964468:3972453397245339817859333Yersinia pestis biovar Microtus str. 91001, complete genomeputative virulence determinant06105
NC_009381:627685:6356696356696450019333Yersinia pestis Pestoides F chromosome, complete genomevirulence determinant06104
NC_017265:854492:8624778624778718099333Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,putative virulence determinant06103
NC_017154:941065:9512089512089605229315Yersinia pestis D106004 chromosome, complete genomevirulence determinant06096
NC_010159:138879:1441581441581534729315Yersinia pestis Angola, complete genomeputative phage minor structural protein06091
NC_010465:933488:9415759415759509079333Yersinia pseudotuberculosis YPIII, complete genomevirulence determinant06011
NC_009708:986918:99513299513210044469315Yersinia pseudotuberculosis IP 31758 chromosome, complete genomephage minor structural protein05873
NC_006155:3779381:3783316378331637926279312Yersinia pseudotuberculosis IP 32953, complete genomepore forming RTX toxin family protein05793
NC_010634:3692321:3696277369627737056099333Yersinia pseudotuberculosis PB1/+, complete genomepore forming RTX toxin family protein05774
NC_012751:594851:6143796143796170422664Candidatus Hamiltonella defensa 5AT (Acyrthosiphon pisum), completeputative RTX-family protein-43e-29133
NC_016944:1547176:15471761547176156081313638Vibrio cholerae IEC224 chromosome I, complete sequenceRTX toxin RtxA2e-28130
NC_016445:1027143:10271431027143104074413602Vibrio cholerae O1 str. 2010EL-1786 chromosome 1, completeRTX toxin RtxA2e-28130
NC_002505:1550108:15501081550108156378413677Vibrio cholerae O1 biovar eltor str. N16961 chromosome I, completeRTX toxin RtxA2e-28130
NC_008800:1459015:1467937146793714742696333Yersinia enterocolitica subsp. enterocolitica 8081 chromosome,putative RTX-family protein2e-23114
NC_015224:3225000:3232254323225432385806327Yersinia enterocolitica subsp. palearctica 105.5R(r) chromosome,putative RTX-family protein1e-22111
NC_012962:3499900:34999003499900351018910290Photorhabdus asymbiotica, complete genomeSimilar to RTX toxin RtxA9e-23111
NC_012962:3499900:35481233548123355871510593Photorhabdus asymbiotica, complete genomeSimilar to RTX toxin RtxA3e-19100
NC_012751:1071589:1075689107568910799784290Candidatus Hamiltonella defensa 5AT (Acyrthosiphon pisum), completeputative RTX-family protein-103e-19100
NC_015224:1514747:1526945152694515310934149Yersinia enterocolitica subsp. palearctica 105.5R(r) chromosome,putative cytotoxin RtxA5e-1792.4
NC_012751:1538500:1549965154996515539123948Candidatus Hamiltonella defensa 5AT (Acyrthosiphon pisum), completeputative RTX-family protein-211e-1691.3