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Query: NC_004088:3505383:3530533 Yersinia pestis KIM, complete genome

Start: 3530533, End: 3532734, Length: 2202

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_005810:3142384:3146694314669431488952202Yersinia pestis biovar Microtus str. 91001, complete genomehypothetical protein01429
NC_010159:3448490:3474671347467134768572187Yersinia pestis Angola, complete genomeputative autotransporter protein01419
NC_003143:875367:9005249005249027102187Yersinia pestis CO92, complete genomehypothetical protein01419
NC_010634:3509880:3535049353504935372352187Yersinia pseudotuberculosis PB1/+, complete genomeouter membrane autotransporter01419
NC_008149:3373229:3398386339838634005722187Yersinia pestis Nepal516, complete genomehypothetical protein01419
NC_008150:513783:5180905180905202762187Yersinia pestis Antiqua, complete genomehypothetical protein01419
NC_006155:3596120:3621289362128936234752187Yersinia pseudotuberculosis IP 32953, complete genomeputative secreted protein with autotransporter domain01419
NC_014029:1146900:1151207115120711533932187Yersinia pestis Z176003 chromosome, complete genomehypothetical protein01419
NC_017154:1089044:1093351109335110955372187Yersinia pestis D106004 chromosome, complete genomehypothetical protein01419
NC_017168:199381:2025642025642047502187Yersinia pestis A1122 chromosome, complete genomehypothetical protein01419
NC_017265:1000342:1004652100465210068382187Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,hypothetical protein01419
NC_010465:1118147:1123160112316011253462187Yersinia pseudotuberculosis YPIII, complete genomeouter membrane autotransporter barrel domain protein01417
NC_009708:1131500:1134705113470511368912187Yersinia pseudotuberculosis IP 31758 chromosome, complete genomeautotransporter protein01417
NC_009381:775357:7785407785407806722133Yersinia pestis Pestoides F chromosome, complete genomehypothetical protein01383
NC_017160:1092839:1096431109643110981341704Yersinia pestis D182038 chromosome, complete genomehypothetical protein01102
NC_010067:2304313:2305345230534523075732229Salmonella enterica subsp. arizonae serovar 62:z4,z23:--, completehypothetical protein01060
NC_017160:1092839:109602210960221096414393Yersinia pestis D182038 chromosome, complete genomehypothetical protein5e-62239
NC_013282:3719500:3731436373143637343422907Cronobacter turicensis, complete genomehypothetical protein4e-0757.4
NC_009832:5214850:5237497523749752405113015Serratia proteamaculans 568, complete genomeouter membrane autotransporter barrel domain3e-0757.4
NC_015566:5197624:5216285521628552193743090Serratia sp. AS12 chromosome, complete genomeouter membrane autotransporter barrel domain-containing protein5e-0757
NC_009832:5214850:5234327523432752374283102Serratia proteamaculans 568, complete genomeouter membrane autotransporter barrel domain9e-0756.2
NC_015388:269301:2743472743472837249378Desulfobacca acetoxidans DSM 11109 chromosome, complete genomeouter membrane autotransporter barrel domain protein3e-0654.3
NC_013517:3948500:3965206396520639679472742Sebaldella termitidis ATCC 33386, complete genomeouter membrane autotransporter barrel domain protein3e-0654.3