Pre_GI: BLASTP Hits

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Query: NC_004088:3505383:3516898 Yersinia pestis KIM, complete genome

Start: 3516898, End: 3518088, Length: 1191

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017265:1000342:1019298101929810204881191Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,general secretion pathway protein L0803
NC_008150:513783:5327365327365339261191Yersinia pestis Antiqua, complete genomegeneral secretion pathway protein L0803
NC_008149:3373229:3384736338473633859261191Yersinia pestis Nepal516, complete genomegeneral secretion pathway protein L0803
NC_006155:3596120:3607639360763936088291191Yersinia pseudotuberculosis IP 32953, complete genomeGeneral secretion pathway protein L0803
NC_005810:3142384:3161343316134331625331191Yersinia pestis biovar Microtus str. 91001, complete genomegeneral secretion pathway protein L0803
NC_009381:775357:7931857931857943751191Yersinia pestis Pestoides F chromosome, complete genomegeneral secretion pathway protein L0803
NC_014029:1146900:1165853116585311670431191Yersinia pestis Z176003 chromosome, complete genomeL-like GSP protein0803
NC_017154:1089044:1107998110799811091881191Yersinia pestis D106004 chromosome, complete genomeL-like GSP protein0803
NC_017160:1092839:1110670111067011118601191Yersinia pestis D182038 chromosome, complete genomeL-like GSP protein0803
NC_017168:199381:2172102172102184001191Yersinia pestis A1122 chromosome, complete genomegeneral secretion pathway protein L0803
NC_010634:3509880:3521399352139935225891191Yersinia pseudotuberculosis PB1/+, complete genomegeneral secretion pathway protein L0803
NC_003143:875367:8868748868748880431170Yersinia pestis CO92, complete genomegeneral secretion pathway protein L0789
NC_009708:1131500:1149372114937211505411170Yersinia pseudotuberculosis IP 31758 chromosome, complete genomegeneral secretion pathway protein L0785
NC_010465:1118147:1137809113780911389991191Yersinia pseudotuberculosis YPIII, complete genomegeneral secretion pathway protein L0780
NC_010159:3448490:3461094346109434622061113Yersinia pestis Angola, complete genome0730
NC_008800:3642679:3654920365492036561161197Yersinia enterocolitica subsp. enterocolitica 8081 chromosome,general secretion pathway protein L6e-55215
NC_015224:1067390:1086757108675710877881032Yersinia enterocolitica subsp. palearctica 105.5R(r) chromosome,General secretion pathway protein L2e-46187
NC_015061:366552:3670073670073681821176Rahnella sp. Y9602 chromosome, complete genomegeneral secretion pathway protein L3e-24113
NC_011663:180889:1853941853941865841191Shewanella baltica OS223 chromosome, complete genomegeneral secretion pathway protein L4e-22105
NC_007954:138410:1395441395441407461203Shewanella denitrificans OS217, complete genomeGeneral secretion pathway L6e-22105
NC_016612:2902628:2942374294237429435791206Klebsiella oxytoca KCTC 1686 chromosome, complete genometype II secretion protein EtpL1e-21104
NC_016818:362548:3747563747563759311176Rahnella aquatilis CIP 78.65 = ATCC 33071 chromosome, completegeneral secretion pathway protein L3e-2099.8
NC_013716:4728500:4745485474548547466091125Citrobacter rodentium ICC168, complete genomeputative T2SS protein L2e-0757.4