Pre_GI: BLASTP Hits

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Query: NC_004088:3505383:3511342 Yersinia pestis KIM, complete genome

Start: 3511342, End: 3511977, Length: 636

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017265:1000342:102540110254011026036636Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,hypothetical protein3e-112404
NC_010465:1118147:114390611439061144541636Yersinia pseudotuberculosis YPIII, complete genomehypothetical protein3e-112404
NC_003143:875367:881326881326881961636Yersinia pestis CO92, complete genomehypothetical protein3e-112404
NC_008149:3373229:337918833791883379823636Yersinia pestis Nepal516, complete genomehypothetical protein3e-112404
NC_010159:3448490:345546834554683456103636Yersinia pestis Angola, complete genomehypothetical protein3e-112404
NC_008150:513783:538838538838539473636Yersinia pestis Antiqua, complete genomehypothetical protein3e-112404
NC_005810:3142384:316876131687613169396636Yersinia pestis biovar Microtus str. 91001, complete genomehypothetical protein3e-112404
NC_009708:1131500:115545111554511156086636Yersinia pseudotuberculosis IP 31758 chromosome, complete genomehypothetical protein3e-112404
NC_014029:1146900:117195611719561172591636Yersinia pestis Z176003 chromosome, complete genomehypothetical protein3e-112404
NC_017154:1089044:111410111141011114736636Yersinia pestis D106004 chromosome, complete genomehypothetical protein3e-112404
NC_017160:1092839:111677311167731117408636Yersinia pestis D182038 chromosome, complete genomehypothetical protein3e-112404
NC_017168:199381:223321223321223956636Yersinia pestis A1122 chromosome, complete genomeputative protein-disulfide isomerase3e-112404
NC_010634:3509880:351585635158563516491636Yersinia pseudotuberculosis PB1/+, complete genomehypothetical protein1e-111402
NC_006155:3596120:360209636020963602731636Yersinia pseudotuberculosis IP 32953, complete genomehypothetical protein1e-111402
NC_008800:3642679:364974836497483650392645Yersinia enterocolitica subsp. enterocolitica 8081 chromosome,hypothetical protein2e-80298
NC_015224:1067390:109255310925531093197645Yersinia enterocolitica subsp. palearctica 105.5R(r) chromosome,hypothetical protein3e-79294
NC_020064:3790472:379047237904723791122651Serratia marcescens FGI94, complete genomeputative protein-disulfide isomerase5e-65247
NC_009656:44500:674376743768138702Pseudomonas aeruginosa PA7 chromosome, complete genomehypothetical protein7e-50196
NC_015675:1721543:174304617430461743684639Mesorhizobium opportunistum WSM2075 chromosome, complete genomehypothetical protein7e-1477.4
NC_019973:1731626:175314017531401753778639Mesorhizobium australicum WSM2073, complete genomeputative protein-disulfide isomerase3e-1375.1
NC_002678:2739829:274371427437142744364651Mesorhizobium loti MAFF303099, complete genomehypothetical protein4e-1374.7
NC_010159:1071937:107565710756571076385729Yersinia pestis Angola, complete genomehypothetical protein2e-1065.9
NC_010465:660207:670198670198670914717Yersinia pseudotuberculosis YPIII, complete genomeputative protein-disulfide isomerase2e-1065.5
NC_006155:4062000:406850040685004069216717Yersinia pseudotuberculosis IP 32953, complete genomehypothetical protein2e-1065.5
NC_010634:4001154:400870640087064009422717Yersinia pseudotuberculosis PB1/+, complete genomehypothetical protein2e-1065.5
NC_008150:3495851:350280135028013503517717Yersinia pestis Antiqua, complete genomehypothetical protein2e-1065.5
NC_008149:587689:601453601453602169717Yersinia pestis Nepal516, complete genomehypothetical protein2e-1065.5
NC_004088:3923804:392990039299003930616717Yersinia pestis KIM, complete genomehypothetical protein2e-1065.5
NC_003143:675622:689923689923690639717Yersinia pestis CO92, complete genomehypothetical protein2e-1065.5
NC_009381:460358:471890471890472606717Yersinia pestis Pestoides F chromosome, complete genomehypothetical protein2e-1065.5
NC_014029:729675:743432743432744148717Yersinia pestis Z176003 chromosome, complete genomehypothetical protein2e-1065.5
NC_017154:671816:685584685584686300717Yersinia pestis D106004 chromosome, complete genomehypothetical protein2e-1065.5
NC_017160:676249:687769687769688485717Yersinia pestis D182038 chromosome, complete genomehypothetical protein2e-1065.5
NC_017265:3790750:379526237952623795978717Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,hypothetical protein2e-1065.5
NC_016043:1043366:104564810456481046292645Taylorella asinigenitalis MCE3 chromosome, complete genomethioredoxin8e-1063.9
NC_012660:4734363:475465647546564755258603Pseudomonas fluorescens SBW25 chromosome, complete genomehypothetical protein1e-0962.8
NC_014914:1678973:168267816826781683322645Taylorella equigenitalis MCE9 chromosome, complete genomeThioredoxin2e-0962.4