Pre_GI: BLASTP Hits

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Query: NC_004088:3505383:3510222 Yersinia pestis KIM, complete genome

Start: 3510222, End: 3511229, Length: 1008

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017265:1000342:102614910261491027036888Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,hypothetical protein2e-162571
NC_008149:3373229:337818833781883379075888Yersinia pestis Nepal516, complete genomehypothetical protein2e-162571
NC_010634:3509880:351485635148563515743888Yersinia pseudotuberculosis PB1/+, complete genomebeta-lactamase domain-containing protein2e-162571
NC_006155:3596120:360109636010963601983888Yersinia pseudotuberculosis IP 32953, complete genomehypothetical protein2e-162571
NC_005810:3142384:316950931695093170396888Yersinia pestis biovar Microtus str. 91001, complete genomehypothetical protein2e-162571
NC_003143:875367:880326880326881213888Yersinia pestis CO92, complete genomehypothetical protein2e-162571
NC_014029:1146900:117270411727041173591888Yersinia pestis Z176003 chromosome, complete genomehypothetical protein2e-162571
NC_017154:1089044:111484911148491115736888Yersinia pestis D106004 chromosome, complete genomehypothetical protein2e-162571
NC_017160:1092839:111752111175211118408888Yersinia pestis D182038 chromosome, complete genomehypothetical protein2e-162571
NC_017168:199381:224069224069224956888Yersinia pestis A1122 chromosome, complete genomehypothetical protein2e-162571
NC_008150:513783:539586539586540473888Yersinia pestis Antiqua, complete genomehypothetical protein2e-162571
NC_010159:3448490:345446834544683455355888Yersinia pestis Angola, complete genomemetallo-beta-lactamase family protein7e-162570
NC_010465:1118147:114465411446541145541888Yersinia pseudotuberculosis YPIII, complete genomebeta-lactamase domain protein9e-162569
NC_009708:1131500:115619911561991157086888Yersinia pseudotuberculosis IP 31758 chromosome, complete genomemetallo-beta-lactamase family protein9e-162569
NC_015224:1067390:109325810932581094145888Yersinia enterocolitica subsp. palearctica 105.5R(r) chromosome,hypothetical protein9e-151533
NC_008800:3642679:364879836487983649685888Yersinia enterocolitica subsp. enterocolitica 8081 chromosome,hypothetical protein2e-148525
NC_009656:44500:664876648767374888Pseudomonas aeruginosa PA7 chromosome, complete genomehypothetical protein6e-98357
NC_015556:819503:829727829727830617891Pseudomonas fulva 12-X chromosome, complete genomebeta-lactamase domain protein2e-97355
NC_010410:3886500:390273239027323903598867Acinetobacter baumannii AYE, complete genomeconserved hypothetical protein; putative exported protein5e-63241
NC_010611:31976:357893578936655867Acinetobacter baumannii ACICU, complete genomeZn-dependent hydrolase, including glyoxylase7e-62238
NC_020063:2531643:255273225527322553589858Enterobacteriaceae bacterium strain FGI 57, complete genomeZn-dependent hydrolase, glyoxylase3e-40165
NC_013592:1602242:162019916201991621092894Dickeya dadantii Ech586, complete genomebeta-lactamase domain-containing protein5e-31135