Pre_GI: BLASTP Hits

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Query: NC_004088:3186954:3199631 Yersinia pestis KIM, complete genome

Start: 3199631, End: 3200773, Length: 1143

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017265:2807302:2819980281998028211221143Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,hypothetical protein0784
NC_008149:3022970:3035639303563930367811143Yersinia pestis Nepal516, complete genomehypothetical protein0784
NC_005810:1413305:1426015142601514271571143Yersinia pestis biovar Microtus str. 91001, complete genomehypothetical protein0784
NC_003143:1441211:1446950144695014480921143Yersinia pestis CO92, complete genomehypothetical protein0784
NC_008150:1147883:1151613115161311527551143Yersinia pestis Antiqua, complete genomehypothetical protein0784
NC_010159:1558000:1563833156383315649751143Yersinia pestis Angola, complete genomehypothetical protein0784
NC_009381:2731965:2744633274463327457751143Yersinia pestis Pestoides F chromosome, complete genomehypothetical protein0784
NC_014029:1512605:1518344151834415194861143Yersinia pestis Z176003 chromosome, complete genomehypothetical protein0784
NC_017154:1454704:1460443146044314615851143Yersinia pestis D106004 chromosome, complete genomehypothetical protein0784
NC_017168:4363000:4369010436901043701521143Yersinia pestis A1122 chromosome, complete genomehypothetical protein0784
NC_010465:3046904:3059631305963130607731143Yersinia pseudotuberculosis YPIII, complete genomehypothetical protein0781
NC_009708:3035798:3048459304845930496011143Yersinia pseudotuberculosis IP 31758 chromosome, complete genomehypothetical protein0778
NC_010634:1565788:1571582157158215727241143Yersinia pseudotuberculosis PB1/+, complete genomehypothetical protein0775
NC_006155:1567306:1573082157308215742241143Yersinia pseudotuberculosis IP 32953, complete genomehypothetical protein0775
NC_017160:1299733:131222613122261313062837Yersinia pestis D182038 chromosome, complete genomehypothetical protein3e-159561
NC_010501:3448389:3448389344838934495701182Pseudomonas putida W619, complete genomehypothetical protein3e-115415
NC_006351:2759708:2801509280150928026931185Burkholderia pseudomallei K96243 chromosome 2, complete sequencehypothetical protein4e-115414
NC_010557:316000:3328583328583340421185Burkholderia ambifaria MC40-6 chromosome 3, complete sequencehypothetical protein5e-111401
NC_016114:7252500:7254283725428372554701188Streptomyces flavogriseus ATCC 33331 chromosome, complete genomefumarylacetoacetate (FAA) hydrolase6e-110397
NC_008541:2119883:2141307214130721425511245Arthrobacter sp. FB24 chromosome 1, complete sequencehypothetical protein4e-106385
NC_013745:104385:104385104385105257873Haloterrigena turkmenica DSM 5511 plasmid pHTUR02, completefumarylacetoacetate (FAA) hydrolase2e-1997.1
NC_006510:1995916:201041620104162011315900Geobacillus kaustophilus HTA426, complete genomehypothetical protein9e-1994.7
NC_014206:1618988:162755816275581628457900Geobacillus sp. C56-T3 chromosome, complete genomefumarylacetoacetate hydrolase1e-1894.7
NC_016943:1314500:134775913477591348706948Blastococcus saxobsidens DD2, complete genomeFumarylacetoacetate (FAA) hydrolase family protein8e-1891.7
NC_007181:1740000:175053817505381751416879Sulfolobus acidocaldarius DSM 639, complete genomehypothetical protein2e-1790.1