Pre_GI: BLASTP Hits

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Query: NC_004088:2937077:2946491 Yersinia pestis KIM, complete genome

Start: 2946491, End: 2947753, Length: 1263

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017265:2557476:2566890256689025681521263Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,hypothetical protein0792
NC_008149:2773139:2782553278255327838151263Yersinia pestis Nepal516, complete genomehypothetical protein0792
NC_008150:905000:9137459137459150071263Yersinia pestis Antiqua, complete genomehypothetical protein0792
NC_005810:1520000:1528785152878515300471263Yersinia pestis biovar Microtus str. 91001, complete genomehypothetical protein0792
NC_003143:1691000:1699881169988117011431263Yersinia pestis CO92, complete genomehypothetical protein0792
NC_009381:1655731:1665145166514516664071263Yersinia pestis Pestoides F chromosome, complete genomehypothetical protein0792
NC_014029:1760948:1774386177438617756481263Yersinia pestis Z176003 chromosome, complete genomehypothetical protein0792
NC_017154:1707500:1716479171647917177411263Yersinia pestis D106004 chromosome, complete genomehypothetical protein0792
NC_017160:2054289:2063703206370320649651263Yersinia pestis D182038 chromosome, complete genomehypothetical protein0792
NC_017168:3948514:3957928395792839591901263Yersinia pestis A1122 chromosome, complete genomehypothetical protein0792
NC_009708:2788855:2798271279827127995331263Yersinia pseudotuberculosis IP 31758 chromosome, complete genomeRND family efflux transporter MFP subunit0791
NC_010159:3169266:3174555317455531758171263Yersinia pestis Angola, complete genomeefflux transporter, RND family, MFP subunit0786
NC_010634:1809500:1818109181810918193711263Yersinia pseudotuberculosis PB1/+, complete genomeRND family efflux transporter MFP subunit0783
NC_006155:1807902:1817900181790018191621263Yersinia pseudotuberculosis IP 32953, complete genomehypothetical protein0783
NC_010465:2820500:2828719282871928299811263Yersinia pseudotuberculosis YPIII, complete genomeefflux transporter, RND family, MFP subunit0778
NC_015224:1703130:1712810171281017140721263Yersinia enterocolitica subsp. palearctica 105.5R(r) chromosome,hypothetical protein1e-142506
NC_008800:3061484:3071142307114230724041263Yersinia enterocolitica subsp. enterocolitica 8081 chromosome,hypothetical protein6e-141500
NC_015976:2900891:2923548292354829247981251Sphingobium sp. SYK-6, complete genomeHlyD family secretion protein2e-30134
NC_013730:5538323:5561068556106855623151248Spirosoma linguale DSM 74, complete genomeefflux transporter, RND family, MFP subunit1e-29131
NC_003228:1870953:1870953187095318722001248Bacteroides fragilis NCTC 9343, complete genomeputative HlyD-family transporter component5e-23108
NC_020156:144707:1447071447071458941188Nonlabens dokdonensis DSW-6, complete genomeefflux transporter, RND family, MFP subunit7e-2098.6
NC_021172:3655206:3658378365837836595921215Hyphomicrobium denitrificans 1NES1, complete genomeRND family efflux transporter MFP subunit9e-0858.5
NC_009092:1874888:1895318189531818963821065Shewanella loihica PV-4, complete genomeefflux transporter, RND family, MFP subunit3e-0756.6
NC_014206:2971304:299208129920812993025945Geobacillus sp. C56-T3 chromosome, complete genomebiotin/lipoyl attachment domain-containing protein8e-0755.5
NC_014541:1414627:1438113143811314391951083Ferrimonas balearica DSM 9799 chromosome, complete genomeefflux transporter, RND family, MFP subunit8e-0755.5
NC_009615:2311352:2334521233452123359331413Parabacteroides distasonis ATCC 8503 chromosome, complete genomeABC transporter permease1e-0655.1
NC_009633:337706:3505363505363516901155Alkaliphilus metalliredigens QYMF chromosome, complete genomeRND family efflux transporter MFP subunit2e-0654.3
NC_015172:2628128:2634989263498926362031215Syntrophobotulus glycolicus DSM 8271 chromosome, complete genomeefflux transporter, RND family, MFP subunit2e-0654.3
NC_009454:1577319:158027115802711581248978Pelotomaculum thermopropionicum SI, complete genomemembrane-fusion protein2e-0653.9
NC_009633:365325:3984453984453996051161Alkaliphilus metalliredigens QYMF chromosome, complete genomeRND family efflux transporter MFP subunit3e-0653.5
NC_014377:1871333:1871333187133318725831251Thermosediminibacter oceani DSM 16646 chromosome, complete genomeefflux transporter, RND family, MFP subunit3e-0653.1
NC_010337:1561430:1590063159006315912831221Heliobacterium modesticaldum Ice1, complete genomehlyd family secretion protein6e-0652.4
NC_015589:626321:6294526294526305821131Desulfotomaculum ruminis DSM 2154 chromosome, complete genomeRND family efflux transporter MFP subunit8e-0652