Pre_GI: BLASTP Hits

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Query: NC_004088:2491303:2511071 Yersinia pestis KIM, complete genome

Start: 2511071, End: 2511919, Length: 849

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017265:2213500:223273522327352233472738Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,putative zinc-binding hydrolase5e-143506
NC_010465:2383219:240294024029402403677738Yersinia pseudotuberculosis YPIII, complete genomePHP domain protein5e-143506
NC_009381:1205900:122558412255841226321738Yersinia pestis Pestoides F chromosome, complete genomeputative hydrolase5e-143506
NC_009708:2347350:236583623658362366573738Yersinia pseudotuberculosis IP 31758 chromosome, complete genomehydrolase5e-143506
NC_014029:2285323:230505923050592305796738Yersinia pestis Z176003 chromosome, complete genomehypothetical protein5e-143506
NC_017168:3433804:345336734533673454104738Yersinia pestis A1122 chromosome, complete genomeputative hydrolase5e-143506
NC_010159:2546590:256620325662032566940738Yersinia pestis Angola, complete genomeputative phosphoesterase2e-142505
NC_015968:1709680:171420017142001714937738Enterobacter asburiae LF7a chromosome, complete genomehydrolase ycdX2e-117421
NC_015663:3466471:350030035003003501040741Enterobacter aerogenes KCTC 2190 chromosome, complete genomeputative hydrolase3e-116417
NC_014121:2629075:264547226454722646209738Enterobacter cloacae subsp. cloacae ATCC 13047 chromosome, completePHP family protein3e-114411
NC_013716:1178383:119628011962801197017738Citrobacter rodentium ICC168, complete genomeputative phosphoesterase3e-110397
NC_016514:1701273:170400717040071704744738Enterobacter cloacae EcWSU1 chromosome, complete genomeprotein YcdX9e-108389
NC_003197:1207597:122608812260881226825738Salmonella typhimurium LT2, complete genomehypothetical protein1e-107389
NC_011147:1763681:176723417672341767971738Salmonella enterica subsp. enterica serovar Paratyphi A strhydrolase1e-107389
NC_003198:1117687:113636411363641137101738Salmonella enterica subsp. enterica serovar Typhi str. CT18,hypothetical protein1e-107389
NC_010102:1979742:198177519817751982512738Salmonella enterica subsp. enterica serovar Paratyphi B str. SPB7,hypothetical protein1e-107389
NC_006511:1770000:177205117720511772788738Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCChypothetical protein1e-107389
NC_011080:1209935:122787512278751228612738Salmonella enterica subsp. enterica serovar Newport str. SL254,putative hydrolase1e-107389
NC_004631:1842050:184408218440821844819738Salmonella enterica subsp. enterica serovar Typhi Ty2, completehypothetical protein1e-107389
NC_006905:1186895:120617412061741206911738Salmonella enterica subsp. enterica serovar Choleraesuis strhypothetical protein1e-107389
NC_011149:1987291:198729119872911988028738Salmonella enterica subsp. enterica serovar Agona str. SL483,putative hydrolase1e-107389
NC_011205:2137696:214017221401722140909738Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853hydrolase1e-107389
NC_011294:2009388:201186420118642012601738Salmonella enterica subsp. enterica serovar Enteritidis strhydrolase1e-107389
NC_012125:2646792:264882426488242649561738Salmonella enterica subsp. enterica serovar Paratyphi C strainhydrolase1e-107389
AC_000091:1083798:109912010991201099857738Escherichia coli W3110 DNA, complete genomepredicted zinc-binding hydrolase1e-107389
NC_000913:1087062:109810210981021098839738Escherichia coli K12, complete genomehypothetical protein1e-107389
NC_017046:1164176:118230111823011183038738Salmonella enterica subsp. enterica serovar Typhimurium str. 798hypothetical protein1e-107389
NC_016863:1165232:118354111835411184278738Salmonella enterica subsp. enterica serovar Typhimurium str. UK-1putative hydrolase1e-107389
NC_016860:1205282:122377412237741224511738Salmonella enterica subsp. enterica serovar Typhimurium strputative hydrolase1e-107389
NC_016857:1163919:118222811822281182965738Salmonella enterica subsp. enterica serovar Typhimurium str. ST4/74putative hydrolase1e-107389
NC_016856:1165941:118425011842501184987738Salmonella enterica subsp. enterica serovar Typhimurium str. 14028Sputative hydrolase1e-107389
NC_016832:1838220:184111718411171841854738Salmonella enterica subsp. enterica serovar Typhi str. P-stx-12,hydrolase1e-107389
NC_016810:1163919:118222811822281182965738Salmonella enterica subsp. enterica serovar Typhimurium strhypothetical protein1e-107389
NC_011094:1166271:118439511843951185132738Salmonella enterica subsp. enterica serovar Schwarzengrund strhydrolase2e-107388
NC_016816:2782373:279550227955022796239738Pantoea ananatis LMG 5342, complete genomePHP domain-containing protein2e-107389
NC_011083:1216500:123043712304371231174738Salmonella enterica subsp. enterica serovar Heidelberg str. SL476,putative hydrolase2e-106385
NC_010468:2809125:281029628102962811033738Escherichia coli ATCC 8739, complete genomePHP domain protein4e-102370
NC_004337:1065609:107376010737601074497738Shigella flexneri 2a str. 301, complete genomehypothetical protein6e-102370
NC_008258:1076922:109314010931401093877738Shigella flexneri 5 str. 8401, complete genomehypothetical protein6e-102370
NC_010067:1782998:178501217850121785749738Salmonella enterica subsp. arizonae serovar 62:z4,z23:--, completehypothetical protein1e-100366
NC_017160:2212806:223280222328022233296495Yersinia pestis D182038 chromosome, complete genomehypothetical protein2e-93342
NC_009092:1599526:163408416340841634827744Shewanella loihica PV-4, complete genomePHP C-terminal domain protein1e-90333
NC_009778:2227627:227269522726952273147453Enterobacter sakazakii ATCC BAA-894, complete genomehypothetical protein1e-65249
NC_017047:1796000:179974817997481800167420Rahnella aquatilis HX2 chromosome, complete genomeputative hydrolase2e-58225
NC_014633:339181:348500348500349249750Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequencePHP domain-containing protein6e-53207
NC_016894:2931213:295346229534622954217756Acetobacterium woodii DSM 1030 chromosome, complete genomeputative hydrolase3e-47189
NC_017047:1796000:181092118109211811355435Rahnella aquatilis HX2 chromosome, complete genomeputative hydrolase4e-45181
NC_009778:2227627:223686522368652237239375Enterobacter sakazakii ATCC BAA-894, complete genomehypothetical protein4e-40165
NC_013517:3997448:401771140177114018442732Sebaldella termitidis ATCC 33386, complete genomePHP domain protein2e-32139
NC_010001:69000:891228912289832711Clostridium phytofermentans ISDg, complete genomePHP domain protein2e-28126
NC_016816:2782373:278885227888522789136285Pantoea ananatis LMG 5342, complete genomehypothetical protein1e-23110
NC_004557:2677155:269319926931992693960762Clostridium tetani E88, complete genomeputative DNA polymerase beta2e-1582.8
NC_013216:4097056:411783341178334118570738Desulfotomaculum acetoxidans DSM 771, complete genomePHP domain protein3e-1582.4
NC_003551:154883:165843165843166553711Methanopyrus kandleri AV19, complete genomePredicted phosphatase of the PHP family3e-1376.3
NC_009662:1285826:1304084130408413057991716Nitratiruptor sp. SB155-2, complete genomefamily X DNA polymerase IV5e-1065.1
NC_016831:947281:98985298985298994089Salmonella enterica subsp. enterica serovar Gallinarum/pullorum8e-0857.8
NC_011274:2044000:20445262044526204461590Salmonella enterica subsp. enterica serovar Gallinarum str. 287/918e-0857.8
NC_014323:2680085:2714539271453927163201782Herbaspirillum seropedicae SmR1 chromosome, complete genomeDNA polymerase IV protein4e-0755.5
NC_006322:2886404:2888778288877828904931716Bacillus licheniformis ATCC 14580, complete genomehypothetical protein6e-0755.1
NC_006270:2886193:2888567288856728902911725Bacillus licheniformis ATCC 14580, complete genomehypothetical protein6e-0755.1
NC_011761:2785660:2789828278982827915581731Acidithiobacillus ferrooxidans ATCC 23270 chromosome, completeDNA polymerase X family protein7e-0651.6
NC_011206:2685499:2689667268966726913971731Acidithiobacillus ferrooxidans ATCC 53993, complete genomePHP domain protein7e-0651.6
NC_015958:2527376:2548421254842125501391719Thermoanaerobacter wiegelii Rt8.B1 chromosome, complete genomePHP domain-containing protein8e-0651.2