Pre_GI: BLASTP Hits

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Query: NC_004088:2491303:2491303 Yersinia pestis KIM, complete genome

Start: 2491303, End: 2492274, Length: 972

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017160:2212806:221280622128062213777972Yersinia pestis D182038 chromosome, complete genomehypothetical protein0665
NC_003143:2309500:232721023272102328181972Yersinia pestis CO92, complete genomehypothetical protein0665
NC_004547:2810151:282880228288022829785984Erwinia carotovora subsp. atroseptica SCRI1043, complete genomehypothetical protein2e-152538
NC_008150:1593500:161152316115231612494972Yersinia pestis Antiqua, complete genomehypothetical protein0665
NC_006155:2378526:239617723961772397148972Yersinia pseudotuberculosis IP 32953, complete genomehypothetical protein0661
NC_011415:2153243:216932721693272170298972Escherichia coli SE11 chromosome, complete genomehypothetical protein3e-147521
NC_009381:1205900:120590012059001206871972Yersinia pestis Pestoides F chromosome, complete genomehypothetical protein0665
NC_014029:2285323:228532322853232286294972Yersinia pestis Z176003 chromosome, complete genomehypothetical protein0665
NC_021150:1322000:134497313449731345932960Azotobacter vinelandii CA6, complete genomemethyltransferase4e-95348
NC_013851:859396:859396859396860373978Allochromatium vinosum DSM 180 chromosome, complete genomemethyltransferase1e-87323
NC_010634:2297000:231407323140732315044972Yersinia pseudotuberculosis PB1/+, complete genomemethyltransferase0661
NC_012560:1322000:134496113449611345920960Azotobacter vinelandii DJ, complete genomemethyltransferase4e-95348
NC_010465:2383219:238321923832192384190972Yersinia pseudotuberculosis YPIII, complete genomemethyltransferase0663
NC_014973:54449:728067280673777972Geobacter sp. M18 chromosome, complete genomemethyltransferase1e-90333
NC_007517:2870657:287375528737552874726972Geobacter metallireducens GS-15, complete genomeMethyltransferase, putative5e-89327
NC_008258:1934479:195271519527151953686972Shigella flexneri 5 str. 8401, complete genomeputative enzyme7e-147520
NC_007384:1320287:132527313252731326244972Shigella sonnei Ss046, complete genomeputative enzyme2e-147521
NC_003910:2175305:219715821971582198126969Colwellia psychrerythraea 34H, complete genomeputative methyltransferase3e-110398
NC_007645:2294553:231035923103592311333975Hahella chejuensis KCTC 2396, complete genomeSAM-dependent methyltransferase6e-93340
NC_017168:3433804:343380434338043434775972Yersinia pestis A1122 chromosome, complete genometRNA mo(5)U34 methyltransferase0665
NC_016822:1304398:130811713081171309088972Shigella sonnei 53G, complete genometRNA mo(5)U34 methyltransferase2e-147521