Pre_GI: BLASTP Hits

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Query: NC_004088:2491303:2490503 Yersinia pestis KIM, complete genome

Start: 2490503, End: 2491306, Length: 804

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017168:3433804:343300434330043433807804Yersinia pestis A1122 chromosome, complete genomehypothetical protein1e-158558
NC_006155:2378526:239714523971452397948804Yersinia pseudotuberculosis IP 32953, complete genomehypothetical protein1e-158558
NC_010465:2383219:238241923824192383222804Yersinia pseudotuberculosis YPIII, complete genomemethyltransferase1e-158558
NC_008150:1593500:161249116124911613294804Yersinia pestis Antiqua, complete genomehypothetical protein1e-158558
NC_010634:2297000:231504123150412315844804Yersinia pseudotuberculosis PB1/+, complete genomemethyltransferase1e-158558
NC_003143:2309500:232817823281782328981804Yersinia pestis CO92, complete genomehypothetical protein1e-158558
NC_009381:1205900:120510012051001205903804Yersinia pestis Pestoides F chromosome, complete genomehypothetical protein1e-158558
NC_014029:2285323:228452322845232285326804Yersinia pestis Z176003 chromosome, complete genomehypothetical protein1e-158558
NC_017160:2212806:221200622120062212809804Yersinia pestis D182038 chromosome, complete genomehypothetical protein1e-158558
NC_008258:1934479:195197519519751952718744Shigella flexneri 5 str. 8401, complete genomehypothetical protein1e-123442
NC_011415:2153243:216858721685872169330744Escherichia coli SE11 chromosome, complete genomehypothetical protein1e-123442
NC_016822:1304398:130908513090851309828744Shigella sonnei 53G, complete genometRNA cmo(5)U34 methyltransferase5e-123440
NC_007384:1320287:132624113262411326984744Shigella sonnei Ss046, complete genomehypothetical protein5e-123440
NC_004547:2810151:282802628280262828805780Erwinia carotovora subsp. atroseptica SCRI1043, complete genomehypothetical protein2e-118424
NC_009348:3029963:306585330658533066596744Aeromonas salmonicida subsp. salmonicida A449, complete genomemethyltransferase, putative3e-94344
NC_013416:1783349:178997017899701790695726Aggregatibacter actinomycetemcomitans D11S-1, complete genomemethyltransferase, putative3e-93341
NC_016513:16721:209662096621691726Aggregatibacter actinomycetemcomitans ANH9381 chromosome, completemethyltransferase2e-92338
NC_012560:1322000:134591713459171346660744Azotobacter vinelandii DJ, complete genomemethyltransferase6e-78290
NC_021150:1322000:134592913459291346672744Azotobacter vinelandii CA6, complete genomemethyltransferase6e-78290
NC_007517:2870657:287472328747232875526804Geobacter metallireducens GS-15, complete genomemethyltransferase1e-75282
NC_014973:54449:720757207572809735Geobacter sp. M18 chromosome, complete genomemethyltransferase3e-75281
NC_007645:2294553:231133023113302312076747Hahella chejuensis KCTC 2396, complete genomeSAM-dependent methyltransferase1e-68259
NC_013851:859396:858668858668859405738Allochromatium vinosum DSM 180 chromosome, complete genomemethyltransferase2e-55215
NC_014551:1872000:189099418909941891722729Bacillus amyloliquefaciens DSM 7, complete genomemethyltransferase1e-34147
NC_015572:1252000:126533912653391266067729Methylomonas methanica MC09 chromosome, complete genometype 12 methyltransferase1e-25117
NC_010634:2124185:214469021446902145415726Yersinia pseudotuberculosis PB1/+, complete genomemethyltransferase type 125e-21101
NC_006155:2208686:222836622283662229091726Yersinia pseudotuberculosis IP 32953, complete genomehypothetical protein5e-21101
NC_014010:1489910:150667215066721507376705Candidatus Puniceispirillum marinum IMCC1322 chromosome, completemethyltransferase domain protein1e-1687
NC_016616:2219486:221948622194862220172687Dechlorosoma suillum PS chromosome, complete genomemethylase involved in ubiquinone/menaquinone biosynthesis2e-0756.2
NC_006582:4256915:426283142628314263676846Bacillus clausii KSM-K16, complete genomehypothetical protein3e-0652.8