Pre_GI: BLASTP Hits

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Query: NC_004088:2366000:2371641 Yersinia pestis KIM, complete genome

Start: 2371641, End: 2372048, Length: 408

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009832:2969376:298269729826972983104408Serratia proteamaculans 568, complete genomehistone family protein nucleoid-structuring protein H-NS6e-35145
NC_006155:2461262:247560124756012476008408Yersinia pseudotuberculosis IP 32953, complete genomeDNA-binding protein Hns1e-34145
NC_010159:2252380:226955522695552269962408Yersinia pestis Angola, complete genomeDNA-binding protein H-NS1e-34145
NC_010634:2376245:239190323919032392310408Yersinia pseudotuberculosis PB1/+, complete genomehistone family protein nucleoid-structuring protein H-NS1e-34145
NC_010465:2282874:230574723057472306154408Yersinia pseudotuberculosis YPIII, complete genomehistone family protein nucleoid-structuring protein H-NS1e-34145
NC_008149:1842500:185677118567711857178408Yersinia pestis Nepal516, complete genomeDNA-binding protein Hns1e-34145
NC_005810:2180303:219597521959752196382408Yersinia pestis biovar Microtus str. 91001, complete genomeglobal DNA-binding transcriptional dual regulator H-NS1e-34145
NC_009708:2245586:226842622684262268833408Yersinia pseudotuberculosis IP 31758 chromosome, complete genomeglobal DNA-binding transcriptional dual regulator H-NS1e-34145
NC_017265:2087487:209333920933392093746408Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,global DNA-binding transcriptional dual regulator H-NS1e-34145
NC_009381:1064227:108635510863551086783429Yersinia pestis Pestoides F chromosome, complete genomeglobal DNA-binding transcriptional dual regulator H-NS8e-35145
NC_008150:1705152:172011917201191720517399Yersinia pestis Antiqua, complete genomeDNA-binding protein Hns1e-33141
NC_003143:2433190:244815724481572448555399Yersinia pestis CO92, complete genomeDNA-binding protein Hns1e-33141
NC_014029:2138000:216494921649492165347399Yersinia pestis Z176003 chromosome, complete genomeDNA-binding protein Hns1e-33141
NC_017154:2430093:244506024450602445458399Yersinia pestis D106004 chromosome, complete genomeDNA-binding protein Hns1e-33141
NC_017160:2054289:209254120925412092939399Yersinia pestis D182038 chromosome, complete genomeDNA-binding protein Hns1e-33141
NC_015061:2867027:287810528781052878512408Rahnella sp. Y9602 chromosome, complete genomehistone family protein nucleoid-structuring protein H-NS2e-33140
NC_017168:3290380:331383833138383314248411Yersinia pestis A1122 chromosome, complete genomeglobal DNA-binding transcriptional dual regulator H-NS2e-33140
NC_014306:2703544:271566027156602716067408Erwinia billingiae Eb661, complete genomeHistone-like nucleoid-structuring protein (H-NS)2e-32137
NC_013421:2453078:247008424700842470491408Pectobacterium wasabiae WPP163, complete genomehistone family protein nucleoid-structuring protein H-NS2e-32137
NC_008800:2448583:245311024531102453520411Yersinia enterocolitica subsp. enterocolitica 8081 chromosome,global DNA-binding transcriptional dual regulator H-NS8e-32135
NC_015224:2618192:262271826227182623128411Yersinia enterocolitica subsp. palearctica 105.5R(r) chromosome,global DNA-binding transcriptional dual regulator H-NS8e-32135
NC_013850:2103469:210815321081532108560408Klebsiella variicola At-22 chromosome, complete genomehistone family protein nucleoid-structuring protein H-NS1e-31135
NC_009778:1477841:148417514841751484588414Enterobacter sakazakii ATCC BAA-894, complete genomehypothetical protein3e-31134
NC_020260:1535394:154307915430791543492414Cronobacter sakazakii Sp291, complete genomeglobal DNA-binding transcriptional dual regulator H-NS3e-31134
NC_015968:2583721:259642225964222596835414Enterobacter asburiae LF7a chromosome, complete genomehistone family protein nucleoid-structuring protein H-NS8e-31132
NC_014121:1653385:165816616581661658579414Enterobacter cloacae subsp. cloacae ATCC 13047 chromosome, completeH-NS protein8e-31132
NC_016514:2647984:266089026608902661303414Enterobacter cloacae EcWSU1 chromosome, complete genomeDNA-binding protein H-NS8e-31132
NC_004431:2185750:221332922133292213733405Escherichia coli CFT073, complete genomeDNA-binding protein H-NS5e-1992.8
NC_008253:1938975:196648719664871966891405Escherichia coli 536, complete genomeputative DNA-binding protein5e-1992.8
NC_013716:2139952:216115221611522161556405Citrobacter rodentium ICC168, complete genomeDNA-binding protein H-NS1e-1892
NC_011205:2180598:220938422093842209788405Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853H-NS histone family protein2e-1890.9
NC_011274:2044000:207349720734972073901405Salmonella enterica subsp. enterica serovar Gallinarum str. 287/91DNA-binding protein2e-1890.9
NC_011294:2053991:208236920823692082773405Salmonella enterica subsp. enterica serovar Enteritidis strDNA-binding protein2e-1890.9
NC_016831:947281:960683960683961087405Salmonella enterica subsp. enterica serovar Gallinarum/pullorumputative DNA-binding protein (histone-like protein hlp-II)2e-1890.9
NC_003384:109036:131457131457131861405Salmonella enterica subsp. enterica serovar Typhi str. CT18 plasmidputative DNA-binding protein4e-1890.1
NC_011745:2209288:226333422633342263738405Escherichia coli ED1a chromosome, complete genomeDNA-binding protein H-NS (Histone-like protein HLP-II)5e-1889.7
NC_016825:158626:158626158626159030405Salmonella enterica subsp. enterica serovar Typhi str. P-stx-12DNA-binding protein H-NS2e-1787.8
NC_004547:3207776:324113032411303241531402Erwinia carotovora subsp. atroseptica SCRI1043, complete genomeDNA-binding protein Hns6e-1786.3
NC_014500:1862000:190280419028041903211408Dickeya dadantii 3937 chromosome, complete genomeDNA-binding protein H-NS4e-1683.6
NC_014500:894136:904677904677905084408Dickeya dadantii 3937 chromosome, complete genomeDNA-binding protein H-NS7e-1682.8
NC_013421:3093995:310667131066713107072402Pectobacterium wasabiae WPP163, complete genomehistone family protein nucleoid-structuring protein H-NS8e-1682.4
NC_004547:1873390:191476319147631915161399Erwinia carotovora subsp. atroseptica SCRI1043, complete genomeDNA-binding protein Hns2e-1581.3
NC_011750:2928990:296562729656272966031405Escherichia coli IAI39 chromosome, complete genomeDNA binding protein, nucleoid-associated4e-1580.1
NC_000913:2746886:279611327961132796517405Escherichia coli K12, complete genomeDNA binding protein, nucleoid-associated3e-1580.1
AP010958:3238742:326061632606163261020405Escherichia coli O103:H2 str. 12009 DNA, complete genomeDNA binding protein StpA, nucleoid-associated3e-1580.1
NC_010473:2839902:288787828878782888282405Escherichia coli str. K-12 substr. DH10B, complete genomeDNA binding protein, nucleoid-associated3e-1580.1
CP002185:2919752:294420629442062944610405Escherichia coli W, complete genomeDNA binding protein, nucleoid-associated3e-1580.1
CU928160:2818750:284300028430002843404405Escherichia coli IAI1 chromosome, complete genomeDNA binding protein, nucleoid-associated3e-1580.1
AC_000091:2747520:279674727967472797151405Escherichia coli W3110 DNA, complete genomeDNA binding protein, nucleoid-associated3e-1580.1
NC_011741:2818750:284300028430002843404405Escherichia coli IAI1 chromosome, complete genomeDNA binding protein, nucleoid-associated3e-1580.1
NC_012759:2633949:268192526819252682329405Escherichia coli BW2952 chromosome, complete genomeDNA binding protein3e-1580.1
NC_012967:2669182:269284426928442693248405Escherichia coli B str. REL606 chromosome, complete genomeDNA binding protein3e-1580.1
NC_013353:3238742:326061632606163261020405Escherichia coli O103:H2 str. 12009, complete genomeDNA binding protein StpA, nucleoid-associated3e-1580.1
NC_013364:3339768:336170533617053362109405Escherichia coli O111:H- str. 11128, complete genomeDNA binding protein StpA, nucleoid-associated3e-1580.1
NC_011742:2863316:288528828852882885692405Escherichia coli S88 chromosome, complete genomeDNA binding protein7e-1579.3
NC_011601:2998326:302395430239543024358405Escherichia coli O127:H6 str. E2348/69 chromosome, complete genomeDNA binding protein6e-1579.3
NC_016612:477407:488100488100488564465Klebsiella oxytoca KCTC 1686 chromosome, complete genomeputative DNA-binding protein2e-1064.3
NC_009350:6987:164801648016890411Aeromonas salmonicida subsp. salmonicida A449 plasmid 5, completehistone-like nucleoid structuring protein4e-0857
NC_015424:3112637:311882531188253119235411Aeromonas veronii B565 chromosome, complete genomehistone-like nucleoid structuring protein8e-0855.8
NC_009350:137645:531531941411Aeromonas salmonicida subsp. salmonicida A449 plasmid 5, completehistone-like nucleoid structuring protein1e-0755.5
NC_008570:2216736:225203222520322252442411Aeromonas hydrophila subsp. hydrophila ATCC 7966, complete genomeDNA-binding protein Hns1e-0755.1
NC_010519:1411347:141313014131301413534405Haemophilus somnus 2336 chromosome, complete genomehistone family protein nucleoid-structuring protein H-NS9e-0752.4
NC_008309:842072:842970842970843374405Haemophilus somnus 129PT, complete genomeDNA-binding protein H-NS1e-0652