Some Help

Query: NC_004088:179775:198375 Yersinia pestis KIM, complete genome

Start: 198375, End: 198743, Length: 369

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

Search Results with any or all of these Fields

Host Accession, e.g. NC_0123..Host Description, e.g. Clostri...
Host Lineage, e.g. archae, Proteo, Firmi...
Host Information, e.g. soil, Thermo, Russia

SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017160:3986844:400544340054434005811369Yersinia pestis D182038 chromosome, complete genomehypothetical protein2e-63240
NC_005810:4381182:440012344001234400491369Yersinia pestis biovar Microtus str. 91001, complete genomehypothetical protein2e-63240
NC_008149:3966586:398518639851863985554369Yersinia pestis Nepal516, complete genomehypothetical protein2e-63240
NC_006155:4210606:422950342295034229871369Yersinia pseudotuberculosis IP 32953, complete genomehypothetical protein1e-61234
NC_017265:4171500:418933141893314189690360Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,hypothetical protein2e-61234
NC_010159:1208699:122927612292761229635360Yersinia pestis Angola, complete genomehypothetical protein2e-60231
NC_010634:4150763:416965141696514170010360Yersinia pseudotuberculosis PB1/+, complete genomehypothetical protein1e-59228
NC_015224:4028150:404504640450464045405360Yersinia enterocolitica subsp. palearctica 105.5R(r) chromosome,Preprotein translocase subunit SecA1e-28125