Pre_GI: BLASTP Hits

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Query: NC_003997:4745027:4763001 Bacillus anthracis str. Ames, complete genome

Start: 4763001, End: 4763759, Length: 759

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This well studied laboratory strain (Porton isolate) is not virulent due to the loss of the two plasmids, pXO1 and pXO2. Under starvation conditions this group of bacteria initiate a pathway that leads to endospore formation, a process that is thoroughly studied and is a model system for prokaryotic development and differentiation. Spores are highly resistant to heat, cold, dessication, radiation, and disinfectants, and enable the organism to persist in otherwise inhospitable environments. Under more inviting conditions the spores germinate to produce vegetative cells. This organism was the first to be shown to cause disease by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. PA/LF and PA/EF complexes are internalized by host cells where the LF (metalloprotease) and EF (calmodulin-dependent adenylate cyclase) components act. At high levels LF induces cell death and release of the bacterium while EF increases host susceptibility to infection and promotes fluid accumulation in the cells.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012659:4745053:476302747630274763785759Bacillus anthracis str. A0248, complete genomehypothetical protein9e-145512
NC_011773:4807911:482399448239944824752759Bacillus cereus AH820 chromosome, complete genomehypothetical protein9e-145512
NC_005945:4747740:476433647643364765094759Bacillus anthracis str. Sterne, complete genomehypothetical protein9e-145512
NC_007530:4744870:476312747631274763885759Bacillus anthracis str. 'Ames Ancestor', complete genomehypothetical protein9e-145512
NC_005957:4757215:477389947738994774657759Bacillus thuringiensis serovar konkukian str. 97-27, completeprobable transcriptional regulator9e-145512
NC_006274:4814601:483172148317214832479759Bacillus cereus E33L, complete genomeprobable transcriptional regulator2e-144511
NC_017200:4814000:483165648316564832414759Bacillus thuringiensis serovar finitimus YBT-020 chromosome,putative transcriptional regulator9e-144509
NC_003909:4737882:475398447539844754742759Bacillus cereus ATCC 10987, complete genomehypothetical protein9e-144509
NC_016771:4692772:471274447127444713502759Bacillus cereus NC7401, complete genomehypothetical protein2e-143508
NC_011969:4680836:469952946995294700287759Bacillus cereus Q1 chromosome, complete genometranscriptional regulator2e-143508
NC_011658:4739951:475888747588874759645759Bacillus cereus AH187 chromosome, complete genomehypothetical protein2e-143508
NC_004722:4899940:491535949153594916117759Bacillus cereus ATCC 14579, complete genomeTranscriptional regulator4e-141500
NC_017208:4996992:501331850133185014076759Bacillus thuringiensis serovar chinensis CT-43 chromosome, completetranscriptional regulator9e-141499
NC_011725:4944072:495961649596164960374759Bacillus cereus B4264 chromosome, complete genomehypothetical protein9e-141499
NC_014171:4812340:482788448278844828642759Bacillus thuringiensis BMB171 chromosome, complete genometranscriptional regulator7e-140496
NC_010184:4791000:480609348060934806851759Bacillus weihenstephanensis KBAB4, complete genometranscriptional regulator, TrmB6e-137486
NC_016935:2503071:254027825402782541093816Paenibacillus mucilaginosus 3016 chromosome, complete genomehypothetical protein5e-1891.7
NC_015690:1967244:200739020073902008205816Paenibacillus mucilaginosus KNP414 chromosome, complete genomehypothetical protein5e-1891.7
NC_009725:2784334:280195928019592802765807Bacillus amyloliquefaciens FZB42, complete genomeputative transcriptional regulator6e-1787.8
NC_014976:759129:761397761397762224828Bacillus subtilis BSn5 chromosome, complete genomeputative transcriptional regulator3e-1685.5
NC_007929:1290568:131195813119581312752795Lactobacillus salivarius subsp. salivarius UCC118, complete genomeTranscriptional regulator3e-1375.9
NC_009523:585367:590923590923591708786Roseiflexus sp. RS-1 chromosome, complete genometranscriptional regulator TrmB4e-1375.1
NC_015186:2197236:221662122166212217559939Acidiphilium multivorum AIU301, complete genomehypothetical protein3e-1168.9
NC_003413:128228:1297061297061307311026Pyrococcus furiosus DSM 3638, complete genomehypothetical protein2e-0962.8
NC_014334:369974:376174376174377004831Lactobacillus casei str. Zhang chromosome, complete genomeputative transcriptional regulator5e-0961.6
NC_010999:349252:352900352900353730831Lactobacillus casei, complete genomeEF0126 (Putative uncharacterized protein)5e-0961.6
NC_013665:257438:262568262568263359792Methanocella paludicola SANAE, complete genomeputative TrmB family transcriptional regulator2e-0859.7
NC_013967:1878045:1880343188034318814611119Haloferax volcanii DS2 chromosome, complete genometranscription regulator3e-0755.8
NC_020291:2291418:231131023113102311870561Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genometranscriptional regulator, TrmB9e-0753.9