Pre_GI: BLASTP Hits

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Query: NC_003997:4507939:4524262 Bacillus anthracis str. Ames, complete genome

Start: 4524262, End: 4525356, Length: 1095

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This well studied laboratory strain (Porton isolate) is not virulent due to the loss of the two plasmids, pXO1 and pXO2. Under starvation conditions this group of bacteria initiate a pathway that leads to endospore formation, a process that is thoroughly studied and is a model system for prokaryotic development and differentiation. Spores are highly resistant to heat, cold, dessication, radiation, and disinfectants, and enable the organism to persist in otherwise inhospitable environments. Under more inviting conditions the spores germinate to produce vegetative cells. This organism was the first to be shown to cause disease by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. PA/LF and PA/EF complexes are internalized by host cells where the LF (metalloprotease) and EF (calmodulin-dependent adenylate cyclase) components act. At high levels LF induces cell death and release of the bacterium while EF increases host susceptibility to infection and promotes fluid accumulation in the cells.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_011773:4569600:4589903458990345909971095Bacillus cereus AH820 chromosome, complete genomespore germination protein GerHB0654
NC_012659:4507966:4524289452428945253831095Bacillus anthracis str. A0248, complete genomespore germination protein GerHB0653
NC_012581:4509491:4526618452661845277121095Bacillus anthracis str. CDC 684 chromosome, complete genomespore germination protein GerHB0653
NC_007530:4507742:4524389452438945254831095Bacillus anthracis str. 'Ames Ancestor', complete genomespore germination protein gerhb0653
NC_005945:4508304:4525473452547345265671095Bacillus anthracis str. Sterne, complete genomespore germination protein GerHB0653
NC_003909:4484278:4504854450485445059541101Bacillus cereus ATCC 10987, complete genomespore germination protein GerHB0645
NC_016771:4445815:4464303446430344654031101Bacillus cereus NC7401, complete genomespore germination protein GerHB0639
NC_011658:4492356:4510520451052045116201101Bacillus cereus AH187 chromosome, complete genomespore germination protein GerHB0639
NC_011969:4432454:4451064445106444521641101Bacillus cereus Q1 chromosome, complete genomespore germination protein ib0639
NC_012472:4515909:4533421453342145345151095Bacillus cereus 03BB102, complete genomespore germination protein GerHB0636
NC_016779:4475425:4492820449282044939141095Bacillus cereus F837/76 chromosome, complete genomeSpore germination protein GerHB/GerIB0636
NC_008600:4509793:4527229452722945283261098Bacillus thuringiensis str. Al Hakam, complete genomespore germination protein IB0636
NC_005957:4502733:4521248452124845223481101Bacillus thuringiensis serovar konkukian str. 97-27, completespore germination protein IB0635
NC_017200:4520482:4536473453647345375671095Bacillus thuringiensis serovar finitimus YBT-020 chromosome,spore germination protein GerHB0634
NC_006274:4563455:4580813458081345819131101Bacillus cereus E33L, complete genomespore germination protein IB2e-179628
NC_011725:4671432:4690591469059146916851095Bacillus cereus B4264 chromosome, complete genomespore germination protein GerHB2e-178625
NC_004722:4645678:4666260466626046673631104Bacillus cereus ATCC 14579, complete genomeSpore germination protein IB2e-176618
NC_014171:4560061:4580525458052545816251101Bacillus thuringiensis BMB171 chromosome, complete genomespore germination protein IB2e-176618
NC_017208:4692478:4709763470976347108631101Bacillus thuringiensis serovar chinensis CT-43 chromosome, completespore germination protein IB5e-172603
NC_010184:4532262:4550052455005245511461095Bacillus weihenstephanensis KBAB4, complete genomespore germination protein1e-160566
NC_011772:4638000:4655297465529746563911095Bacillus cereus G9842, complete genomespore germination protein GerHB2e-156551
NC_006274:765870:7664257664257675341110Bacillus cereus E33L, complete genomespore germination protein B5e-66251
NC_011777:161505:1630491630491641431095Bacillus cereus AH820 plasmid pAH820_272, complete sequencespore germination protein B2e-39163
NC_012659:3320933:3338236333823633393331098Bacillus anthracis str. A0248, complete genomespore germination protein4e-2099.4
NC_012581:897957:8993088993089004051098Bacillus anthracis str. CDC 684 chromosome, complete genomespore germination protein4e-2099.4
NC_003997:3320906:3338209333820933393061098Bacillus anthracis str. Ames, complete genomespore germination protein4e-2099.4
NC_007530:3321033:3338336333833633394331098Bacillus anthracis str. 'Ames Ancestor', complete genomespore germination protein4e-2099.4
NC_005945:3321600:3338903333890333400001098Bacillus anthracis str. Sterne, complete genomespore germination protein4e-2099.4
NC_011773:3399531:3418080341808034191771098Bacillus cereus AH820 chromosome, complete genomespore germination protein4e-2099.4
NC_016935:2347691:2361586236158623626831098Paenibacillus mucilaginosus 3016 chromosome, complete genomespore germination protein3e-1583.2
NC_015690:1818333:1831715183171518328121098Paenibacillus mucilaginosus KNP414 chromosome, complete genomespore germination protein3e-1582.8
NC_019896:2158223:2159427215942721605181092Bacillus subtilis subsp. subtilis str. BSP1 chromosome, completehypothetical protein8e-1478.2
NC_017195:1852935:1891080189108018921711092Bacillus subtilis subsp. subtilis str. RO-NN-1 chromosome, completeputative spore germination protein YndE1e-1377.8
NC_020244:1875834:1914795191479519158861092Bacillus subtilis XF-1, complete genomeputative spore germination integral inner membrane protein6e-1375.5
NC_004193:375416:5095575095575106601104Oceanobacillus iheyensis HTE831, complete genomespore germination protein9e-1374.7
NC_015425:2072703:2071592207159220727101119Clostridium botulinum BKT015925 chromosome, complete genomespore germination protein1e-0964.3
NC_013406:3329791:3350642335064233517301089Paenibacillus sp. Y412MC10 chromosome, complete genomespore germination protein2e-0963.5
UCMB5137:2894511:2914278291427829153811104Bacillus atrophaeus UCMB-5137GerA germination receptor protein3e-0962.8