Pre_GI: BLASTP Hits

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Query: NC_003997:4507939:4520724 Bacillus anthracis str. Ames, complete genome

Start: 4520724, End: 4521848, Length: 1125

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This well studied laboratory strain (Porton isolate) is not virulent due to the loss of the two plasmids, pXO1 and pXO2. Under starvation conditions this group of bacteria initiate a pathway that leads to endospore formation, a process that is thoroughly studied and is a model system for prokaryotic development and differentiation. Spores are highly resistant to heat, cold, dessication, radiation, and disinfectants, and enable the organism to persist in otherwise inhospitable environments. Under more inviting conditions the spores germinate to produce vegetative cells. This organism was the first to be shown to cause disease by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. PA/LF and PA/EF complexes are internalized by host cells where the LF (metalloprotease) and EF (calmodulin-dependent adenylate cyclase) components act. At high levels LF induces cell death and release of the bacterium while EF increases host susceptibility to infection and promotes fluid accumulation in the cells.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012659:4507966:4520751452075145218751125Bacillus anthracis str. A0248, complete genomehomoserine O-acetyltransferase0788
NC_012581:4509491:4523158452315845242821125Bacillus anthracis str. CDC 684 chromosome, complete genomehomoserine O-acetyltransferase0788
NC_007530:4507742:4520851452085145219751125Bacillus anthracis str. 'Ames Ancestor', complete genomehomoserine O-acetyltransferase0788
NC_005945:4508304:4521935452193545230591125Bacillus anthracis str. Sterne, complete genomehomoserine O-acetyltransferase0788
NC_012472:4515909:4529962452996245310861125Bacillus cereus 03BB102, complete genomeputative homoserine O-acetyltransferase0780
NC_008600:4509793:4523773452377345248971125Bacillus thuringiensis str. Al Hakam, complete genomehomoserine O-acetyltransferase0777
NC_016779:4475425:4489478448947844906021125Bacillus cereus F837/76 chromosome, complete genomehomoserine O-acetyltransferase0776
NC_006274:4563455:4577311457731145784351125Bacillus cereus E33L, complete genomehomoserine O-acetyltransferase0775
NC_014335:4442500:4457279445727944584031125Bacillus cereus biovar anthracis str. CI chromosome, completehomoserine O-acetyltransferase0774
NC_005957:4502733:4517632451763245187561125Bacillus thuringiensis serovar konkukian str. 97-27, completehomoserine O-acetyltransferase0771
NC_011773:4569600:4586443458644345875671125Bacillus cereus AH820 chromosome, complete genomehomoserine O-acetyltransferase0754
NC_017200:4520482:4533190453319045343141125Bacillus thuringiensis serovar finitimus YBT-020 chromosome,homoserine O-acetyltransferase0751
NC_003909:4484278:4501355450135545024791125Bacillus cereus ATCC 10987, complete genomehomoserine O-acetyltransferase0748
NC_016771:4445815:4461014446101444621381125Bacillus cereus NC7401, complete genomehomoserine O-acetyltransferase0744
NC_011658:4492356:4507231450723145083551125Bacillus cereus AH187 chromosome, complete genomehomoserine O-acetyltransferase0744
NC_011772:4638000:4651739465173946528631125Bacillus cereus G9842, complete genomeputative homoserine O-acetyltransferase0737
NC_004722:4645678:4662783466278346639071125Bacillus cereus ATCC 14579, complete genomehomoserine O-acetyltransferase0737
NC_011725:4671432:4687033468703346881571125Bacillus cereus B4264 chromosome, complete genomehomoserine O-acetyltransferase0731
NC_017208:4692478:4706555470655547076791125Bacillus thuringiensis serovar chinensis CT-43 chromosome, completehomoserine O-acetyltransferase0725
NC_010184:4532262:4546800454680045479241125Bacillus weihenstephanensis KBAB4, complete genomehomoserine O-acetyltransferase, putative0720
NC_011969:4432454:4447643444764344486921050Bacillus cereus Q1 chromosome, complete genomehomoserine o-acetyltransferase0700
NC_014171:4560061:457716145771614578159999Bacillus thuringiensis BMB171 chromosome, complete genomehomoserine O-acetyltransferase0659
NC_013855:670285:6702856702856715051221Azospirillum sp. B510 plasmid pAB510a, complete sequencehomoserine O-acetyltransferase2e-66253
NC_016041:2420098:2421406242140624227401335Glaciecola nitratireducens FR1064 chromosome, complete genomehomoserine O-acetyltransferase6e-63241
NC_002939:2697767:2700316270031627014221107Geobacter sulfurreducens PCA, complete genomehomoserine O-acetyltransferase2e-59229
NC_014836:993448:1012254101225410133661113Desulfurispirillum indicum S5 chromosome, complete genomehomoserine O-acetyltransferase3e-55216
NC_017079:2157733:2159468215946821607001233Caldilinea aerophila DSM 14535 = NBRC 104270, complete genomehomoserine O-acetyltransferase7e-53207
NC_014720:1737574:1742034174203417432301197Caldicellulosiruptor kronotskyensis 2002 chromosome, completehomoserine o-acetyltransferase2e-52206
NC_014002:403180:4044814044814059321452Methanohalophilus mahii DSM 5219 chromosome, complete genomehomoserine O-acetyltransferase7e-50197
NC_009662:1285826:1289712128971212908211110Nitratiruptor sp. SB155-2, complete genomehomoserine O-acetyltransferase2e-48193
NC_008340:362000:3818963818963830501155Alkalilimnicola ehrlichei MLHE-1, complete genomehomoserine O-acetyltransferase1e-48193
NC_009802:1659257:1677980167798016790861107Campylobacter concisus 13826, complete genomehomoserine O-acetyltransferase5e-47188
NC_007681:770267:7869087869087883801473Methanosphaera stadtmanae DSM 3091, complete genomeMetX1e-46187
NC_014166:1424754:1427937142793714290431107Arcobacter nitrofigilis DSM 7299 chromosome, complete genomehomoserine O-acetyltransferase2e-45183
NC_017187:1305805:1311510131151013126191110Arcobacter butzleri ED-1, complete genomehomoserine O-acetyltransferase1e-44181
NC_007925:4756236:4778369477836947795711203Rhodopseudomonas palustris BisB18, complete genomehomoserine O-acetyltransferase8e-44177
NC_009656:475465:4970454970454981841140Pseudomonas aeruginosa PA7 chromosome, complete genomehomoserine O-acetyltransferase2e-43177
NC_013922:1911338:1911338191133819125521215Natrialba magadii ATCC 43099 chromosome, complete genomehomoserine O-acetyltransferase4e-43175
NC_012559:2854640:2873203287320328743451143Laribacter hongkongensis HLHK9, complete genomeMetX2e-42173
NC_007958:4541110:4562581456258145637801200Rhodopseudomonas palustris BisB5, complete genomehomoserine O-acetyltransferase3e-42172
NC_011004:5283648:5305950530595053071491200Rhodopseudomonas palustris TIE-1, complete genomehomoserine O-acetyltransferase4e-41169
NC_005296:4985991:5008280500828050094821203Rhodopseudomonas palustris CGA009, complete genomehomoserine O-acetyltransferase8e-41167
NC_015684:3340519:3362191336219133633991209Oligotropha carboxidovorans OM5 chromosome, complete genomehomoserine O-acetyltransferase MetX1e-40167
NC_020541:2551539:2555696255569625568051110Rhodanobacter sp. 2APBS1, complete genomehomoserine O-acetyltransferase3e-39162
NC_009720:2143124:2158995215899521602151221Xanthobacter autotrophicus Py2, complete genomehomoserine O-acetyltransferase4e-39162
NC_006677:215466:2168082168082179981191Gluconobacter oxydans 621H, complete genomehomoserine O-acetyltransferase1e-37157
NC_015387:942974:9663629663629675101149Marinithermus hydrothermalis DSM 14884 chromosome, complete genomeHomoserine O-acetyltransferase3e-37156
NC_013510:1637730:1659116165911616601831068Thermomonospora curvata DSM 43183, complete genomehomoserine O-acetyltransferase1e-36154
NC_020209:397376:4407244407244418481125Pseudomonas poae RE*1-1-14, complete genomehomoserine O-acetyltransferase1e-36154
NC_015186:597695:5983455983455994901146Acidiphilium multivorum AIU301, complete genomehomoserine O-acetyltransferase2e-36153
NC_009484:489398:4893984893984905431146Acidiphilium cryptum JF-5 chromosome, complete genomehomoserine O-acetyltransferase6e-36151
NC_016783:537717:5535185535185546211104Corynebacterium diphtheriae INCA 402 chromosome, complete genomehomoserine O-acetyltransferase9e-33141
NC_016147:1825827:1829924182992418310661143Pseudoxanthomonas spadix BD-a59 chromosome, complete genomehomoserine O-acetyltransferase1e-32140
NC_016786:533537:5493395493395504421104Corynebacterium diphtheriae HC01 chromosome, complete genomehomoserine O-acetyltransferase3e-32139
NC_016782:537412:5493685493685504711104Corynebacterium diphtheriae 241 chromosome, complete genomehomoserine O-acetyltransferase3e-32139
NC_014659:3654979:3656349365634936574341086Rhodococcus equi 103S, complete genomehomoserine O-acetyltransferase MetA1e-31137
NC_016788:527351:5393055393055404081104Corynebacterium diphtheriae HC04 chromosome, complete genomehomoserine O-acetyltransferase2e-31137
NC_016887:1093609:1110613111061311117611149Nocardia cyriacigeorgica GUH-2, complete genomeHomoserine O-acetyltransferase (Homoserine O-trans-acetylase) (Homoserine transacetylase) (HTA)2e-28126
NC_016025:65923:8963489634906981065Candidatus Chloracidobacterium thermophilum B chromosome chromosomehomoserine O-acetyltransferase8e-28124
NC_009342:841500:8537508537508548831134Corynebacterium glutamicum R chromosome, complete genomehomoserine O-acetyltransferase3e-26119
NC_013169:474856:4748564748564759711116Kytococcus sedentarius DSM 20547, complete genomehomoserine O-acetyltransferase5e-23108
NC_015574:806762:822927822927823916990Methanobacterium sp. SWAN-1 chromosome, complete genomeHomoserine O-acetyltransferase3e-22106
NC_013235:402819:4054474054474065261080Nakamurella multipartita DSM 44233, complete genomealpha/beta hydrolase fold protein4e-22105
NC_019976:22705:4750947509486211113Natronococcus occultus SP4 plasmid 2, complete sequencehomoserine acetyltransferase3e-21103
NC_018644:1197897:1197897119789711989131017Alpha proteobacterium HIMB59 chromosome, complete genomealpha/beta hydrolase family protein5e-21102
NC_014010:1850500:1904749190474919057651017Candidatus Puniceispirillum marinum IMCC1322 chromosome, completeHomoserine O-acetyltransferase2e-1997.4
NC_008826:539835:5673325673325683751044Methylibium petroleiphilum PM1 plasmid RPME01, complete sequenceHomoserine O-acetyltransferase8e-1995.1
NC_008146:20047:4596745967469951029Mycobacterium sp. MCS, complete genomeHomoserine O-acetyltransferase2e-1790.1
NC_008705:27434:5330753307543351029Mycobacterium sp. KMS, complete genomeHomoserine O-acetyltransferase2e-1790.1
NC_016631:4423658:4442216444221644433161101Granulicella mallensis MP5ACTX8 chromosome, complete genomehomoserine O-acetyltransferase2e-1584
NC_013757:1888850:1903209190320919042701062Geodermatophilus obscurus DSM 43160, complete genomealpha/beta hydrolase fold protein1e-1377.8
NC_007005:3199820:3205149320514932062191071Pseudomonas syringae pv. syringae B728a, complete genomehypothetical protein2e-1377.4
NC_016935:1636278:1729087172908717301061020Paenibacillus mucilaginosus 3016 chromosome, complete genomealpha/beta hydrolase fold protein2e-1273.9
NC_015690:1109335:1163782116378211648011020Paenibacillus mucilaginosus KNP414 chromosome, complete genomealpha/beta hydrolase fold protein2e-1273.9
NC_007948:3502843:3518815351881535198341020Polaromonas sp. JS666, complete genomeHomoserine O-acetyltransferase3e-1272.8
NC_013406:3975512:3981533398153339825551023Paenibacillus sp. Y412MC10 chromosome, complete genomehypothetical protein4e-1272.8
NC_008571:365047:3687483687483697611014Gramella forsetii KT0803, complete genomehomoserine O-acetyltransferase2e-1170.5
NC_016631:3917253:3921492392149239226581167Granulicella mallensis MP5ACTX8 chromosome, complete genomehomoserine O-acetyltransferase6e-1065.5
NC_017338:14886:155781557816546969Staphylococcus aureus subsp. aureus JKD6159 chromosome, completehomoserine O-acetyltransferase3e-0756.6