Pre_GI: BLASTP Hits

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Query: NC_003997:4507939:4517757 Bacillus anthracis str. Ames, complete genome

Start: 4517757, End: 4519166, Length: 1410

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This well studied laboratory strain (Porton isolate) is not virulent due to the loss of the two plasmids, pXO1 and pXO2. Under starvation conditions this group of bacteria initiate a pathway that leads to endospore formation, a process that is thoroughly studied and is a model system for prokaryotic development and differentiation. Spores are highly resistant to heat, cold, dessication, radiation, and disinfectants, and enable the organism to persist in otherwise inhospitable environments. Under more inviting conditions the spores germinate to produce vegetative cells. This organism was the first to be shown to cause disease by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. PA/LF and PA/EF complexes are internalized by host cells where the LF (metalloprotease) and EF (calmodulin-dependent adenylate cyclase) components act. At high levels LF induces cell death and release of the bacterium while EF increases host susceptibility to infection and promotes fluid accumulation in the cells.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_011773:4569600:4581226458122645848853660Bacillus cereus AH820 chromosome, complete genomecollagen triple helix repeat domain protein2e-70267
NC_005957:4502733:4512919451291945160863168Bacillus thuringiensis serovar konkukian str. 97-27, completecollagen-like protein3e-70266
NC_011969:4432454:4442150444215044461423993Bacillus cereus Q1 chromosome, complete genomecollagen triple helix repeat domain protein3e-69262
NC_006274:4563455:4573318457331845757652448Bacillus cereus E33L, complete genomecollagen-like protein7e-69261
NC_014335:4442500:4453160445316044557212562Bacillus cereus biovar anthracis str. CI chromosome, completecollagen triple helix repeat domain-containing protein2e-68260
NC_012581:4509491:4519309451930945216002292Bacillus anthracis str. CDC 684 chromosome, complete genomecollagen triple helix repeat domain protein4e-68259
NC_004722:4645678:4657356465735646612853930Bacillus cereus ATCC 14579, complete genomehypothetical Membrane Spanning Protein9e-68258
NC_011725:4671432:4681641468164146855343894Bacillus cereus B4264 chromosome, complete genomecollagen triple helix repeat domain protein7e-68258
NC_005945:4508304:4518446451844645203891944Bacillus anthracis str. Sterne, complete genomecollagen triple helix repeat domain protein1e-67257
NC_012472:4515909:4525753452575345284042652Bacillus cereus 03BB102, complete genomecollagen triple helix repeat domain protein2e-67256
NC_016779:4475425:4485269448526944879202652Bacillus cereus F837/76 chromosome, complete genomePhage tail fiber protein2e-67256
NC_011772:4638000:4647385464738546502402856Bacillus cereus G9842, complete genomecollagen triple helix repeat domain protein3e-67256
NC_011658:4492356:4502218450221845057303513Bacillus cereus AH187 chromosome, complete genomecollagen triple helix repeat domain-containing protein5e-67255
NC_016771:4445815:4456001445600144595133513Bacillus cereus NC7401, complete genomehypothetical protein5e-67255
NC_008600:4509793:4519636451963645222272592Bacillus thuringiensis str. Al Hakam, complete genomecollagen-like protein5e-67255
NC_012659:4507966:4517784451778445191931410Bacillus anthracis str. A0248, complete genomecollagen triple helix repeat domain protein7e-67254
NC_007530:4507742:4517884451788445192931410Bacillus anthracis str. 'Ames Ancestor', complete genomecollagen triple helix repeat domain protein7e-67254
NC_003909:4484278:4495891449589144998563966Bacillus cereus ATCC 10987, complete genomecollagen triple helix repeat domain protein3e-66253
NC_017208:4692478:4702398470239847050552658Bacillus thuringiensis serovar chinensis CT-43 chromosome, completehypothetical protein8e-64244
NC_017200:4520482:4530342453034245315261185Bacillus thuringiensis serovar finitimus YBT-020 chromosome,collagen triple helix repeat domain protein1e-62240
NC_010184:4532262:4542493454249345452972805Bacillus weihenstephanensis KBAB4, complete genomeCollagen triple helix repeat1e-59231
NC_011658:4301633:4314721431472143160011281Bacillus cereus AH187 chromosome, complete genomecollagen triple helix repeat domain-containing protein6e-55215
NC_011969:4235818:4247550424755042488931344Bacillus cereus Q1 chromosome, complete genomehypothetical protein6e-55215
NC_005957:4311679:4324767432476743259391173Bacillus thuringiensis serovar konkukian str. 97-27, completeconserved hypothetical protein, collagen triple helix repeat domain1e-54214
NC_014976:627935:641858641858642580723Bacillus subtilis BSn5 chromosome, complete genomecollagen triple helix repeat domain-containing protein3e-26120
NC_014171:4560061:457173545717354571881147Bacillus thuringiensis BMB171 chromosome, complete genomehypothetical protein4e-1583.2