Pre_GI: BLASTP Hits

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Query: NC_003997:4507939:4512459 Bacillus anthracis str. Ames, complete genome

Start: 4512459, End: 4512692, Length: 234

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This well studied laboratory strain (Porton isolate) is not virulent due to the loss of the two plasmids, pXO1 and pXO2. Under starvation conditions this group of bacteria initiate a pathway that leads to endospore formation, a process that is thoroughly studied and is a model system for prokaryotic development and differentiation. Spores are highly resistant to heat, cold, dessication, radiation, and disinfectants, and enable the organism to persist in otherwise inhospitable environments. Under more inviting conditions the spores germinate to produce vegetative cells. This organism was the first to be shown to cause disease by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. PA/LF and PA/EF complexes are internalized by host cells where the LF (metalloprotease) and EF (calmodulin-dependent adenylate cyclase) components act. At high levels LF induces cell death and release of the bacterium while EF increases host susceptibility to infection and promotes fluid accumulation in the cells.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012659:4507966:451248645124864512719234Bacillus anthracis str. A0248, complete genomemolybdopterin converting factor, subunit 17e-37152
NC_012581:4509491:451401145140114514244234Bacillus anthracis str. CDC 684 chromosome, complete genomemolybdopterin converting factor subunit 17e-37152
NC_005945:4508304:451314845131484513381234Bacillus anthracis str. Sterne, complete genomemolybdopterin converting factor, subunit 17e-37152
NC_007530:4507742:451258645125864512819234Bacillus anthracis str. 'Ames Ancestor', complete genomemolybdopterin converting factor, subunit 17e-37152
NC_011773:4569600:457593045759304576163234Bacillus cereus AH820 chromosome, complete genomemolybdopterin converting factor subunit 13e-36150
NC_014335:4442500:444638244463824446615234Bacillus cereus biovar anthracis str. CI chromosome, completemolybdopterin converting factor subunit 13e-36150
NC_006274:4563455:456802145680214568254234Bacillus cereus E33L, complete genomemolybdopterin converting factor, subunit 16e-36149
NC_012472:4515909:452047645204764520709234Bacillus cereus 03BB102, complete genomemolybdopterin converting factor, subunit 13e-35147
NC_008600:4509793:451435945143594514592234Bacillus thuringiensis str. Al Hakam, complete genomemolybdopterin converting factor, subunit 13e-35147
NC_016779:4475425:447999244799924480225234Bacillus cereus F837/76 chromosome, complete genomemolybdopterin converting factor subunit 13e-35147
NC_017200:4520482:452504745250474525280234Bacillus thuringiensis serovar finitimus YBT-020 chromosome,molybdopterin converting factor subunit 15e-35146
NC_003909:4484278:449064344906434490876234Bacillus cereus ATCC 10987, complete genomemolybdopterin converting factor, subunit 14e-34143
NC_005957:4502733:450762345076234507856234Bacillus thuringiensis serovar konkukian str. 97-27, completemolybdopterin converting factor, subunit 17e-34142
NC_011658:4492356:449692244969224497155234Bacillus cereus AH187 chromosome, complete genomemolybdopterin converting factor subunit 17e-34142
NC_011969:4432454:443522744352274435460234Bacillus cereus Q1 chromosome, complete genomemolybdopterin converting factor subunit 17e-34142
NC_016771:4445815:445070544507054450938234Bacillus cereus NC7401, complete genomemolybdopterin converting factor subunit 17e-34142
NC_010184:4532262:453716945371694537402234Bacillus weihenstephanensis KBAB4, complete genomemolybdopterin converting factor, subunit 14e-33139
NC_011772:4638000:464206346420634642296234Bacillus cereus G9842, complete genomemolybdopterin converting factor, subunit 16e-33139
NC_017208:4692478:469707746970774697310234Bacillus thuringiensis serovar chinensis CT-43 chromosome, completemolybdopterin (MPT) converting factor subunit 12e-32137
NC_011725:4671432:467632046763204676553234Bacillus cereus B4264 chromosome, complete genomemolybdopterin converting factor subunit 12e-32137
NC_014171:4560061:456641445664144566647234Bacillus thuringiensis BMB171 chromosome, complete genomemolybdopterin (MPT) converting factor subunit 13e-32136
NC_004722:4645678:465203646520364652269234Bacillus cereus ATCC 14579, complete genomeMolybdopterin (MPT) converting factor, subunit 13e-32136
NC_011773:3399531:340633034063303406566237Bacillus cereus AH820 chromosome, complete genomemolybdopterin converting factor subunit 14e-1580.1
NC_012659:3320933:332663733266373326873237Bacillus anthracis str. A0248, complete genomemolybdopterin converting factor, subunit 12e-1477.8
NC_012581:897957:911769911769912005237Bacillus anthracis str. CDC 684 chromosome, complete genomemolybdopterin converting factor subunit 12e-1477.8
NC_007530:3321033:332673733267373326973237Bacillus anthracis str. 'Ames Ancestor', complete genomemolybdopterin converting factor, subunit 12e-1477.8
NC_003997:3320906:332661033266103326846237Bacillus anthracis str. Ames, complete genomemolybdopterin converting factor, subunit 12e-1477.8
NC_005945:3321600:332730433273043327570267Bacillus anthracis str. Sterne, complete genomemolybdopterin converting factor, subunit 12e-1477.4
NC_006510:795973:798190798190798420231Geobacillus kaustophilus HTA426, complete genomemolybdopterin converting factor (subunit 1)1e-1271.6
NC_014008:354292:387448387448387687240Coraliomargarita akajimensis DSM 45221 chromosome, complete genomethiamineS protein1e-0755.1
NC_011901:3072817:309354030935403093773234Thioalkalivibrio sulfidophilus HL-EbGr7 chromosome, completemolybdopterin converting factor, subunit 14e-0753.1
NC_016112:3840053:384487638448763845115240Methylomicrobium alcaliphilum chromosome, complete genomesulfur transfer protein ThiS6e-0752.8
NC_014147:765941:765941765941766192252Moraxella catarrhalis RH4 chromosome, complete genomeputative molybdopterin synthase subunit MoaD8e-0752.4
NC_008025:316302:324989324989325663675Deinococcus geothermalis DSM 11300, complete genomemolybdopterin converting factor, subunit 19e-0752.4
NC_013889:2603914:260435326043532604586234Thioalkalivibrio sp. K90mix chromosome, complete genomemolybdopterin converting factor, subunit 14e-0650.1
NC_012526:2483000:249497724949772495669693Deinococcus deserti VCD115, complete genomeputative molybdenum cofactor biosynthesis protein, small and large subunit6e-0649.3
NC_012438:50845:707207072070962243Sulfurihydrogenibium azorense Az-Fu1 chromosome, complete genomehypothetical protein1e-0548.9