Pre_GI: BLASTP Hits

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Query: NC_003997:4473973:4490883 Bacillus anthracis str. Ames, complete genome

Start: 4490883, End: 4491197, Length: 315

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This well studied laboratory strain (Porton isolate) is not virulent due to the loss of the two plasmids, pXO1 and pXO2. Under starvation conditions this group of bacteria initiate a pathway that leads to endospore formation, a process that is thoroughly studied and is a model system for prokaryotic development and differentiation. Spores are highly resistant to heat, cold, dessication, radiation, and disinfectants, and enable the organism to persist in otherwise inhospitable environments. Under more inviting conditions the spores germinate to produce vegetative cells. This organism was the first to be shown to cause disease by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. PA/LF and PA/EF complexes are internalized by host cells where the LF (metalloprotease) and EF (calmodulin-dependent adenylate cyclase) components act. At high levels LF induces cell death and release of the bacterium while EF increases host susceptibility to infection and promotes fluid accumulation in the cells.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017208:4662500:467542246754224675736315Bacillus thuringiensis serovar chinensis CT-43 chromosome, completethioredoxin4e-55213
NC_007530:4474000:449101044910104491324315Bacillus anthracis str. 'Ames Ancestor', complete genomethioredoxin family protein4e-55213
NC_005957:4472800:448596244859624486276315Bacillus thuringiensis serovar konkukian str. 97-27, completethioredoxin4e-55213
NC_014335:4414052:442483544248354425149315Bacillus cereus biovar anthracis str. CI chromosome, completethioredoxin family protein4e-55213
NC_004722:4614442:463027146302714630585315Bacillus cereus ATCC 14579, complete genomeThioredoxin4e-55213
NC_005945:4473790:449157244915724491886315Bacillus anthracis str. Sterne, complete genomethioredoxin family protein4e-55213
NC_011772:4606000:462039346203934620707315Bacillus cereus G9842, complete genomethioredoxin family protein4e-55213
NC_011725:4636521:465454446545444654858315Bacillus cereus B4264 chromosome, complete genomethioredoxin4e-55213
NC_011773:4541306:455439045543904554704315Bacillus cereus AH820 chromosome, complete genomethioredoxin family protein4e-55213
NC_012581:4478036:449243444924344492748315Bacillus anthracis str. CDC 684 chromosome, complete genomethioredoxin family protein4e-55213
NC_012659:4474000:449091044909104491224315Bacillus anthracis str. A0248, complete genomethioredoxin family protein4e-55213
NC_017200:4484399:450115945011594501473315Bacillus thuringiensis serovar finitimus YBT-020 chromosome,thioredoxin1e-54211
NC_011969:4396000:441329844132984413612315Bacillus cereus Q1 chromosome, complete genomethioredoxin2e-54211
NC_010184:4497473:451559945155994515913315Bacillus weihenstephanensis KBAB4, complete genomeThioredoxin domain9e-54208
UCMB5137:2054735:210387821038782104195318Bacillus atrophaeus UCMB-5137putative thiol-disulfide oxidoreductase with thiroedoxin domain3e-36150
NC_017353:1235095:124196912419691242280312Staphylococcus lugdunensis N920143, complete genomeputative thioredoxin2e-25114
NC_021175:155152:156626156626156940315Streptococcus oligofermentans AS 1.3089, complete genomehypothetical protein1e-23108
NC_014727:1485656:150251715025171502837321Lactobacillus delbrueckii subsp. bulgaricus ND02 chromosome,thiol-disulfide isomerase and thioredoxin1e-22104
NC_015759:726612:738512738512738835324Weissella koreensis KACC 15510 chromosome, complete genomethioredoxin5e-22102
NC_008525:108687:110656110656110976321Pediococcus pentosaceus ATCC 25745, complete genomeThiol-disulfide isomerase and thioredoxin9e-1992
NC_017337:853221:875891875891876211321Staphylococcus aureus subsp. aureus ED133 chromosome, completethioredoxin6e-1682.8
NC_014650:2969866:299524929952492995569321Geobacillus sp. Y4.1MC1 chromosome, complete genomethioredoxin domain-containing protein2e-1580.9
NC_010556:316996:350663350663350986324Exiguobacterium sibiricum 255-15, complete genomeThioredoxin domain9e-1579
NC_004193:375416:375416375416675301299886Oceanobacillus iheyensis HTE831, complete genome2e-1374.3
NC_004193:375416:620621620621620941321Oceanobacillus iheyensis HTE831, complete genomethioredoxin3e-1270.1
NC_011999:558057:575411575411575734324Macrococcus caseolyticus JCSC5402, complete genomethioredoxin homolog1e-1065.5
NC_011529:766292:772400772400772717318Thermococcus onnurineus NA1, complete genomehypothetical protein5e-0959.7
NC_018643:1080514:108794810879481088268321Alpha proteobacterium HIMB5 chromosome, complete genomeThioredoxin2e-0858.2
NC_012883:1522920:153303215330321533337306Thermococcus sibiricus MM 739, complete genomeThioredoxin3e-0857
NC_008229:118000:118006118006118320315Helicobacter acinonychis str. Sheeba, complete genomethioredoxin7e-0752.8
NC_014804:1183780:119352411935241193829306Thermococcus barophilus MP chromosome, complete genomehypothetical protein8e-0752.4